Acular PF Information

What's inside Acular PF

Acular PF in the News

United Microelectronics Dec. Sales Increase 1.10 - RTT News
From the earlier research, PF-03187207 has been selected and is presently in its phase 2 clinical developments. Two separate studies are also ongoing in the ...
Tue Jan 08 02:34:42 -0500 2008

NicOx signs extension of ophthalmology agreement with Pfizer - FOX News
The selected candidate from this earlier agreement, PF-03187207, is in phase 2 clinical development and two separate studies are currently ongoing in the ...
Tue Jan 08 02:21:54 -0500 2008

Pfizer begins phase 2 trial of experimental glaucoma treatment - OSN SuperSite (subscription)
The treatment, called PF-03187207, contains nitric oxide-donating prostaglandin F2-alpha analogs for the reduction of IOP and was co-developed by Pfizer and ...
Fri Jan 04 11:04:51 -0500 2008

Acular PF Chemical Information

ketorolac tromethamine - The tromethamine salt form of ketorolac, a synthetic pyrrolizine carboxylic acid derivative with anti-inflammatory, analgesic and antipyretic properties. Ketorolac, a non-selective inhibitor of the cyclo-oxygenase (COX) enzyme, prevents the synthesis of prostaglandins and thromboxanes from arachidonic acid. COX enzymes exist in two isoforms; inhibition of the COX-2 enzyme produces the anti-inflammatory and analgesic whereas, inhibition of the COX-1 enzyme is associated with gastrointestinal side effects, nephrotoxicity and platelet de-aggregatory effects.