Advair Diskus Information

Advair Diskus

Advair Diskus is used to control asthma and chronic obstructive pulmonary disease (COPD) associated with chronic bronchitis. It is an oral inhaler that contains two types of medication. One is fluticasone propionate, a steroid that reduces inflammation in the lungs. The other, salmeterol, is a long-acting bronchodilator that opens up the airways. Together, the two ingredients provide better symptom control than either does individually.

Advair Diskus is used for long-term control of asthma and short-term control of COPD associated with bronchitis. The drug won't end a sudden attack. For relief of acute asthma or bronchial symptoms, your doctor will prescribe a short-acting inhaler such as albuterol sulfate.

http://www.drugs.com/pdr/advair-diskus.html

What's inside Advair Diskus

Recent Advair Diskus Side Effects

Posted by harris99 7 days ago
I am a 45 year old black female who was placed on Avdair in September of 2009. In the beginning before Advair, I had never had any respiratory problems. It began with wheezing only at night lying down and slight chest congestion. My doctor diagnosed me with acute bronchitis and placed me on antibiotic Zithromax which did not completely clear me up, so he prescribed Bactrim for 10days which did. I thought I was home free until maybe 3-5 days after completion of the antibiotics, I started wheezing again one night and the next morning I was severely short of breath. I was able to get through that morninig long enough to get to my doctor, who prescribed Advair 50/100 twice daily. I was very skeptical about taking it, but when you think this breath will be your last, then you do what you have to do. I've been on Advair now for 6 months and It has been the miracle drug for me so far. I tried to wean myself off 3weeks afterwards, but have been unsuccessful. My throat starts to close after missing 2 doses and the asthma symptoms return. The only side effects I have had is a froggy throat,decreased smell and taste sensation, sneezing upon awakening and a little weight gain which may or may not be related since I am so preoccupied with breathing that I am not watching my diet or exercising regularly. I was very depressed about having to be on Advair since this is so life altering for me. I asked my doctor what caused all of this and he said it is allery related, he did not give me an asthma diagnosis. I just know that this works for me and I have come to the conclusion that I will be on it for the rest of my life. I am still in disbelief that this suddenly happened to me, but life throws you lemons sometimes. Im happy that Advair is my lemonade!

Posted by lab1130 about 1 month ago
I have been dealing with allergy-induced asthma for twenty years. I can go for months at a time without any problems and be hit with severe respiratory problems within minutes if I'm in the wrong environment (mold, pollen, etc.). I started using Advair four years ago--and would only use it when I knew allergy season was about to hit in the spring and fall. I didn't notice any problematic side effects. However, this summer, with the H1N1 scare, I decided to to be proactive and started taking my Advair twice daily. I've been doing so for the past six months and I have gained 10 lbs. I workout 6 to 7 days per week--1 to 1.5 hours cardio plus weight training. My eating habits have not changed. I've had the H1N1 vaccination and will be going off the Advair to see if my weight goes back down.

Posted by michelle1956 3 months ago
i have had excruciating pain in my right knee and upper part of my right leg while only being on Advair diskus 250/50 for about 3 weeks now. It did help with my wheezing however i cant sleep at night because of the muscle pain i have been having. I NEVER have had issues with either of my knees and am seriously considering stopping the Advair!!!

Advair Diskus in the News

Witty: No rivals coming for Advair - FiercePharma
Witty: No rivals coming for AdvairFiercePharmaAdvair is administered via inhaler and is approved for patients with asthma and COPD. Advair Diskus toted up $4.4 billion in US sales in 2008, ...and more »
Wed Jan 13 16:07:18 +0000 2010

Summertime use of combo inhaler may reduce asthma events in the fall - news Stories
Summertime use of combo inhaler may reduce asthma events in the fallnews StoriesThe study was supported by GlaxoSmithKline of Research Triangle Park, North Carolina, which markets fluticasone propionate/salmeterol as Advair Diskus.
Fri Jan 01 08:05:47 +0000 2010

GSK reveals speaker, consulting fees - Medical Marketing and Media
GSK reveals speaker, consulting feesMedical Marketing and MediaGSK's asthma/COPD treatment Advair Diskus was the fourth best-selling drug in the US in 2008, according to IMS Health. Deirdre Connelly, GSK's president ...and more »
Tue Dec 15 18:04:03 +0000 2009

Advair Diskus Chemical Information

fluticasone propionate - The propionate salt form of fluticasone, a synthetic trifluorinated glucocorticoid receptor agonist with antiallergic, antiinflammatory and antipruritic effects. Binding and activation of the glucocorticoid receptor results in the activation of lipocortin that in turn inhibits cytosolic phospholipase A2, which triggers cascade of reactions involved in synthesis of inflammatory mediators, such as prostaglandins and leukotrienes. Secondly, mitogen-activated protein kinase (MAPK) phosphatase 1 is induced, thereby leads to dephosphorylation and inactivation of Jun N-terminal kinase directly inhibiting c-Jun mediated transcription. Finally, transcriptional activity of nuclear factor (NF)-kappa-B is blocked, thereby inhibits the transcription of cyclooxygenase 2, which is essential for prostaglandin production.

salmeterol xinafoate