Altoprev Information

What's inside Altoprev

Altoprev in the News

BUYINS.NET: (SCRX) SqueezeTrigger Price is $22.027. There is ... - Trading Markets (press release)
As part of the transaction, it acquired the worldwide rights to sell Fortamet and Altoprev. The Company also entered into a long-term manufacturing and ...
Wed Feb 27 04:44:52 -0500 2008

Sciele Pharma Announces FDA Acceptance of NDA for Summers ... - Genetic Engineering News (press release)
We may be unable to develop or market line extensions for our products including Prenate, Sular, Triglide, Nitrolingual, Altoprev and Fortamet, or, ...
Thu Aug 16 06:02:36 -0400 2007

Sciele Pharma Announces FDA Acceptance of NDA for Summers ... - dBusinessNews Atlanta (press release)
We may be unable to develop or market line extensions for our products including Prenate, Sular, Triglide, Nitrolingual, Altoprev and Fortamet, or, ...
Fri Aug 17 02:02:42 -0400 2007

Altoprev Chemical Information

lovastatin - A lactone metabolite isolated from the fungus Aspergillus terreus with cholesterol-lowering activity and potential antineoplastic activity. Lovastatin is hydrolyszed to the active beta-hydroxyacid form, which competitively inhibits 3-hydroxyl-3-methylgutarylcoenzyme A (HMG-CoA) reductase, an enzyme involved in the cholesterol biosynthesis. In addition, this agent may inhibit tumor cell proliferation and reduce tumor cell invasiveness, thereby decreasing tumor metastatic potential; induce tumor cell apoptosis, possibly by inhibiting protein geranylgeranylation and; arrest cells in the G1 phase of the cell cycle, an effect that sensitizes tumor cells to the cytotoxic effects of ionizing radiation. (NCI04)