Sulfamethoxazole and trimethoprim are both antibiotics that treat different types of infection caused by bacteria. The combination of sulfamethoxazole and trimethoprim is used to treat ear infections, urinary tract infections, bronchitis, traveler's diarrhea, and Pneumocystis carinii pneumonia. Sulfamethoxazole and trimethoprim may also be used for other purposes not listed in this medication guide. Take this medication exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label. Measure liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one. Take this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Sulfamethoxazole and trimethoprim will not treat a viral infection such as the common cold or flu. Drink plenty of fluids to prevent kidney stones while you are taking trimethoprim and sulfamethoxazole. Store the tablets and liquid at room temperature away from moisture, heat, and light. ; You should not use this medication if you are allergic to sulfamethoxazole or trimethoprim, if you are pregnant or breast-feeding, or if you have anemia (lack of red blood cells) caused by folic acid deficiency.
| Bactrim Dosages & Strengths | ||||
|---|---|---|---|---|
| Strength | Format | Route | Strength | Class |
| Bactrim 400 mg-80 mg | tablet | oral | 1.0 each | OTC |
| Bactrim 400 mg-80 mg | tablet | oral | 1.0 each | OTC |
Posted by debsie72 4 days ago
Had severe middle ear infection in both ears. Dr stated most antibiotics are for 7 days, but I would need the bactrim for 10. By 10th day (yesterday), my ears are still congested and crackling, and I had symptoms of fever-the chills, then hot. But, I never had a temp. Felt a bit nauseous. Figured I was coming down w/something that everyone at work had. My neck had a tiny bump that was itchy-that's it. Called Dr and they prescribed more bactrim since the ear infection wasn't cleared up. Last night, my ears started burning, and were itchy(the outer cartiledge, not inside). My upper arms were itchy, as well as my back. I took a closer look @ my back, and there are millions of small red bumps. This morning, the bumps are on my neck, entire arms, even my legs down to a few spots on my feet ! I called Dr's office, they are prescribing something different, and told me to get Benadryl. This is so awful-I feel like crap, and can't stop itching !!! To hell with bactrim.
Posted by bepee 4 days ago
I took bactrim last night for a uti. 2 hours after taking I began throwing up and continued to do so for 8 hours in 20 minute intervals. Then I got diarrhea that is still going. It been almost 20 hours. I went to the E.R. For fluids and they gave me morphine for the pain in my lower back, knees, and uti pain. I will never ever take this medicine again. It feels like food poisoning and I'm completely dehydrated again. I can't wait until this goes away.
Posted by liveandlearn 6 days ago
I started taking Bactrim to treat Epididymitis, so also related to UTI. The first 6 days went by fine, I didn not notice anything special. (I did not sleep good as usual. but I did not think anything about it) The 6th night I got moderate fever and could almost not sleep, restless, heart beating faster than usual - very annoying, but not scary. The fever stayed, but went down a few hours if I took paracetamol, after which it came back again. Day 7 I went to the doctor, my first question was "could this be the bactrim?". No way, the doctor said, allergic reaction of bactrim is different, you clearly have all symptoms of a virus. So don't stop taking the bactrim, rest a lot because the virus we cannot do much about that, you have to sit it out. the rest of the day situation remained the same. Day 8th in the afternoon, my symptoms are getting significantly worse! Higher fever, and the worst headache ever experienced. Also a sore neck, painfull glands in neck and chin. Fever, that only moderately goes down from the paracetamol at that point. Cold hands and feet while having fever - 38.6 centigrade temp (metric). That is the point where I say, ok now I go browse the net a bit, cause I dont trust this one bit. The progressive worsening of symptoms seem to me to be an indication this might be other than a flu or similar virus. Off course I think about meningitis, start reading up on that. But when I google "bactrim fever" tons of pages appear like these.. with again and again very similar stories like mine!! I know we have to be very sceptical about what people post, but in this case the long list of testimonies is the missing key of the puzzle to me. It is likely to be the bactrim causing this.
The bad thing is I just took one an hour ago!! now I have to sit it out ... and I feel the worst so far!! I called the doc (at 11pm) and she was receptive about my theory on the bactrim reaction now.
Anyway, I hope I survive the coming night, I am confident I will but it just doesn't feel like it right now. I just wish I had found this website earlier....
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sulfamethoxazole - A broad-spectrum, short-acting sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with antibacterial property. Sulfamethoxazole competes with PABA for the bacterial enzyme dihydropteroate synthase, thereby preventing the incorporation of PABA into dihydrofolic acid, the immediate precursor of folic acid. This leads to an inhibition of bacterial folic acid synthesis and de novo synthesis of purines and pyrimidines, ultimately resulting in cell growth arrest and cell death.
trimethoprim - A synthetic derivative of trimethoxybenzyl-pyrimidine with antibacterial and antiprotozoal properties. As a pyrimidine inhibitor of bacterial dihydrofolate reductase, trimethoprim binds tightly to the bacterial enzyme, blocking the production of tetrahydrofolic acid from dihydrofolic acid. The antibacterial activity of this agent is potentiated by sulfonamides. (NCI04)