Bricanyl Information

What's inside Bricanyl

Bricanyl in the News

Puff justice - Sunday Herald
Terbutaline is the active ingredient of the Bricanyl inhaler he has used for many years. However, when he was granted a Therapeutic Use Exemption (TUE) he ...
Sun Mar 02 06:36:50 -0500 2008

Scott MacLeod warned but can play on - Telegraph.co.uk
MacLeod explained he refers to the medicine by one of its brand names, Bricanyl which added to the confusion. "I actually specified at the time I gave the ...
Mon Feb 25 19:24:02 -0500 2008

MacLeod test a warning sign for SRU - Scotsman
MacLeod had used Bricanyl to treat chronic asthma until 2006, and then changed to a different type of inhaler which the authorities also permitted if an ...
Mon Feb 25 19:07:01 -0500 2008

Bricanyl Chemical Information

terbutaline sulfate - The sulfate salt form of terbutaline, an ethanolamine derivative with bronchodilating and tocolytic properties. Terbutaline sulfate selectively binds to and activates beta-2 adrenergic receptors, leading to intracellular adenyl cyclase activation via a trimeric G protein and subsequent increase in cyclic cAMP production. Increased cAMP levels result in relaxation of bronchial and vascular smooth muscle mediated through the activation of protein kinase A (PKA), which phosphorylates proteins in control of muscle tone. cAMP also inhibits calcium ion release from intracellular stores, reduces calcium entry into cells and induces the sequestration of intracellular calcium all of which aids the relaxation of airway muscles. Terbutaline sulfate also increases mucociliary clearance and reduces release of inflammatory cell mediators.