| Buprenex Dosages & Strengths | ||||
|---|---|---|---|---|
| Strength | Format | Route | Strength | Class |
| Buprenex 0.3 mg/mL | solution | injectable | 1.0 milliliter(s) | OTC |
Tolerance develops with an doctors face laboratory. - Autoweb.cz
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Thu Jun 21 09:53:24 -0400 2007
buprenorphine hydrochloride - The hydrochloride salt form of buprenorphine, a synthetic phenanthrene with narcotic analgesic activity. Buprenorphine hydrochloride is a partial agonist at the mu-opioid receptor and an antagonist at the kapa-opioid receptor in the central nervous system. However, under the conditions of recommended use it behaves as a classic mu-opioid agonist, mimicking the actions of endogenous peptides at CNS opioid receptors. The agonist action results in a raised pain threshold and increased tolerance to pain. However, it also causes sedation, physical dependence, and respiratory depressant effects and decreases heart rate and blood pressure.