Combipatch Information

What's inside Combipatch

Recent Combipatch Side Effects

Posted by lkk8305 about 1 year ago
I have been on Combipatch for 2 months, after switching from another BC. I am experiencing clear discharge frequently and am ...

Combipatch in the News

Noven Reports Second Quarter 2007 Financial Results - Business Wire (press release)
... the risk that Novogyne may not be able to realize the full value of the marketing rights for Noven's CombiPatch product; and risks and uncertainties ...
Tue Aug 07 04:49:53 -0400 2007

Combipatch Chemical Information

estradiol - The most potent form of the naturally occurring steroid sex hormone in humans, produced by ovary, placenta, testis, and in small amount by adrenal cortex. Estradiol binds to a specific intracellular estrogen receptor located in female organs, breasts, hypothalamus and pituitary. The receptor-ligand complex promotes gene expression necessary for the maintenance of fertility and secondary sexual characteristics in females. In addition, estradiol exhibits mild anabolic and metabolic properties, and increases blood coagulability. Estradiol, the principal intracellular human estrogen, is substantially more active at the cellular level than its metabolites, estrone and estriol.

norethindrone - The acetate salt form of norethindrone, a synthetic progestational substance with some anabolic, estrogenic, and androgenic properties. Norethindrone binds to the progesterone intracellular receptors in the reproductive system and the resultant activated complex interacts with specific DNA sites. This leads to an alteration in protein synthesis and results in an inhibition of LH release. Consequently, it inhibits ovulation and changes the normal cycle of cervical mucus and endometrium.