Desowen Information
What's inside Desowen
Desowen Active Ingredients: desonide, details.| Desowen Dosages & Strengths | ||||
|---|---|---|---|---|
| Strength | Format | Route | Strength | Class |
| Desowen 0.05% | ointment | topical | 100.0 gram(s) | OTC |
| Desowen 0.05% | lotion | topical | 100.0 milliliter(s) | OTC |
| Desowen 0.05% | cream | topical | 100.0 gram(s) | OTC |
Desowen Chemical Information
desonide - A synthetic glucocorticosteroid for topical use, with anti-inflammatory activity. Desonide binds to glucocorticoid receptors in the cytoplasm, and the ligand-receptor complex is translocated as a homodimer into the nucleus, where transcription activation via glucocorticoid response elements within glucocorticoid-responsive genes occur. This agent induces transcription of genes coding for anti-inflammatory proteins, including lipocortin-1, interleukin-10, interleukin-1 receptor antagonist and neutral endopeptidase. Increased synthesis of lipocortin-1 has an inhibitory effect on phospholipase A2, which in turn inhibits the release arachidonic acid, thereby controlling the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes.
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