Donnatal Information
What's inside Donnatal
Donnatal Active Ingredients: scopolamine hydrobromide, atropine sulfate, hyoscyamine sulfate, phenobarbital, details.| Donnatal Dosages & Strengths | ||||
|---|---|---|---|---|
| Strength | Format | Route | Strength | Class |
| Donnatal 0.0194 mg-0.1037 mg-16.2 mg-0.0065 mg | tablet | oral | 1.0 each | OTC |
| Donnatal 0.0194 mg-0.1037 mg-16.2 mg-0.0065 mg | tablet | oral | 1.0 each | OTC |
| Donnatal 0.0194 mg-0.1037 mg-16.2 mg-0.0065 mg | tablet | oral | 1.0 each | OTC |
| Donnatal 0.0194 mg-0.1037 mg-16.2 mg-0.0065 mg | tablet | oral | 1.0 each | OTC |
| Donnatal 0.0194 mg-0.1037 mg-16.2 mg-0.0065 mg/5 mL | elixir | oral | 5.0 milliliter(s) | OTC |
| Donnatal 0.0194 mg-0.1037 mg-16.2 mg-0.0065 mg/5 mL | elixir | oral | 5.0 milliliter(s) | OTC |
| Donnatal 0.0194 mg-0.1037 mg-16.2 mg-0.0065 mg/5 mL | elixir | oral | 5.0 milliliter(s) | OTC |
| Donnatal 0.0194 mg-0.1037 mg-16.2 mg-0.0065 mg/5 mL | elixir | oral | 5.0 milliliter(s) | OTC |
| Donnatal 0.0194 mg-0.1037 mg-16.2 mg-0.0065 mg | capsule | oral | 1.0 each | OTC |
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Donnatal Chemical Information
scopolamine hydrobromide - The hydrobromide salt form of scopolamine, a tropane alkaloid derived from plants of the nightshade family (Solanaceae), specifically Hyoscyamus niger and Atropa belladonna, with anticholinergic, antiemetic and antivertigo properties. Structurally similar to acetylcholine, scopolamine antagonizes acetylcholine activity mediated by muscarinic receptors located on structures innervated by postganglionic cholinergic nerves as well as on smooth muscles that respond to acetylcholine but lack cholinergic innervation. The agent is used to cause mydriasis, cycloplegia, to control the secretion of saliva and gastric acid, to slow gut motility, and prevent vomiting.
atropine sulfate - The sulfate salt of atropine, a naturally-occurring alkaloid isolated from the plant Atropa belladonna. Atropine functions as a sympathetic, competitive antagonist of muscarinic cholinergic receptors, thereby abolishing the effects of parasympathetic stimulation. This agent may induce tachycardia, inhibit secretions, and relax smooth muscles. (NCI04)
hyoscyamine sulfate
phenobarbital - A long-acting barbituric acid derivative with antipsychotic property. Phenobarbital binds to and activates the gamma-aminobutyric acid (GABA)-A receptor, thereby mimicking the inhibitory actions of GABA in the brain. The activation effects of the phenobarbital-receptor-ionophore complex include increased frequency of chloride channel openings, membrane hyperpolarization and ultimately synaptic inhibition and decreased neuronal excitability. In addition, this agent inhibits glutamate induced depolarization.
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