Epivir HBV Information
What's inside Epivir HBV
Epivir HBV Active Ingredients: lamivudine, details.| Epivir HBV Dosages & Strengths | ||||
|---|---|---|---|---|
| Strength | Format | Route | Strength | Class |
| Epivir HBV 100 mg | tablet | oral | 1.0 each | OTC |
| Epivir HBV 5 mg/mL | solution | oral | 1.0 milliliter(s) | OTC |
Epivir HBV in the News
IAS: ART interruption particularly unsafe for HIV-positive ... - Aidsmap
Opportunistic disease and mortality in patients coinfected with hepatitis C virus (HCV) and/or hepatitis B virus (HBV) in the SMART (Strategic Management of ...
Tue Jul 24 08:01:02 -0400 2007
Gilead's Phase III HBV Data: Viread Stacks Up To Hepsera - BioWorld Online
... but he wrote that Viread's efficacy looks "as good or better" than marketed HBV drugs, including Baraclude, Epivir (lamivudine, GlaxoSmithKline plc), ...
Thu Jun 07 21:10:10 -0400 2007
Epivir HBV Chemical Information
lamivudine - A synthetic nucleoside analogue with activity against hepatitis B virus (HBV) and HIV. Intracellularly, lamivudine is phosphorylated to its active metabolites, lamiduvine triphosphate (L-TP) and lamiduvine monophosphate (L-MP). In HIV, L-TP inhibits HIV-1 reverse transcriptase (RT) via DNA chain termination after incorporation of the nucleoside analogue into viral DNA. In HBV, incorporation of L-MP into viral DNA by HBV polymerase results in DNA chain termination. L-TP is a weak inhibitor of mammalian DNA polymerases alpha and beta, and mitochondrial DNA polymerase. (NCI04)
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