Floxin Information

Floxin

Ofloxacin is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class [1][2] considered to be a second-generation fluoroquinolone. Floxin (branded version) had been discontinued by the manufacturer, in the United States, effective June 18, 2009, though generic equivalents continue to be available.

Ofloxacin is a racemic mixture, which consists of 50% levofloxacin (the biologically active component) and 50% of its “mirror image” or enantiomer dextrofloxacin. When levofloxacin disks were not available in early clinical trials, a 5-pg Floxin (ofloxacin – floxacin) disk was substituted. The U.S. Food and Drug Administration (FDA) medical reviewers considered the two drugs to be one and the same and hence interchangeable.

What's inside Floxin

Recent Floxin Side Effects

Posted by erica29569 3 months ago
Extreme dizziness,Headache,Nausea,and Severe Panic attacks

Posted by bobphillips over 4 years ago
Extreme anxiety, sleeplessness, depression. I have the same reactions from Levaquin

Posted by julietrs over 6 years ago
birth defects including, seizure disorder (uncontrolled at times) microcephaly (musculoskeletal system disorder) partial agenesis of the Corpus Collosum(CNS/ Corpus Collosum partially absent) cerebral palsy(gross motor delay) milk allergy & constipation(both trigger seizures) urogenital malformation

Floxin in the News

Doctors warn bacteria are racing past drugs - San Francisco Chronicle
... has also reduced the effectiveness of the entire family of related antibiotics called fluoroquinolones - drugs such as Levaquin, Floxin and Noroxin. ...
Sun Jan 20 15:09:39 +0000 2008

Johnson & Johnson Wins Levaquin Drug Patent Ruling in Canada - Bloomberg
Levaquin and Floxin, a similar antibiotic, accounted for $1.16 billion in US sales last year, but only $59 million outside the country, Johnson & Johnson ...
Thu Dec 06 13:52:41 +0000 2007

Article by Astrid Spain and Deborah Cadena Ph.D - Mondaq News Alerts (subcription)
all 4 news articles
Wed Nov 07 13:09:00 +0000 2007

Floxin Chemical Information

ofloxacin - A fluoroquinolone antibacterial antibiotic. Ofloxacin binds to and inhibits bacterial topoisomerase II (DNA gyrase) and topoisomerase IV, enzymes involved in DNA replication and repair, resulting in cell death in sensitive bacterial species. (NCI04)