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Fluocinonide Information

Fluocinonide

Fluocinonide is a potent glucocorticoid steroid used topically as anti-inflammatory agent for the treatment of skin disorders such as eczema. It relieves itching, redness, dryness, crusting, scaling, inflammation, and discomfort.

The usual prescription concentration is 0.05% as a topical cream, ointment, or gel. The application area should normally not be covered after application. In certain cases, the physician may recommend the use of an occlusive dressing after application in order to increase the rate and depth of absorption. The frequency of application depends on the condition being treated and the area affected, but most often application should occur two times a day.

What's inside Fluocinonide

Fluocinonide Active Ingredients: fluocinonide, details.
Fluocinonide Dosages & Strengths
Strength Format Route Strength Class
Fluocinonide 0.05% solution topical 100.0 milliliter(s) OTC
Fluocinonide 0.05% ointment topical 100.0 gram(s) OTC
Fluocinonide 0.05% cream topical 100.0 gram(s) OTC
Fluocinonide 0.05% gel topical 100.0 gram(s) OTC
Fluocinonide - powder compounding 100.0 gram(s) OTC

Recent Fluocinonide Side Effects

Posted by actjack18 over 5 years ago
I have been using Fluocinonide Cream USP, 0.05%. I have been using this to treat Psoriasis. I was wondering if this cream causes white blemishes or patches when it it applied to the affected area over time. If so is there anything to treat these white patches.

Posted by szczesniak over 6 years ago
I don't think it is exactly a side effect. I am using it for a red, itchy (tiny blisters) that seems to spread from one location to another on myself. It started with my face, then went to my arms, and now on my hip areas and legs. My doctor said this should work, but not so far very effective. It is also very difficult to go about a normal day because by wearing your clothing the ointment does not stay on to well. My doctor now told me to keep on it, but it does not relieve itching very much.

Fluocinonide in the News

Medicis Reports Fourth Quarter and Year End 2007 Financial Results - FOXBusiness
... LIDEX(R) (fluocinonide) Cream, 0.05%, VANOS(R) (fluocinonide) Cream, 0.1%, and ZIANA(R) (clindamycin phosphate 1.2% and tretinoin 0.025%) Gel, ...
Thu Feb 28 06:12:57 +0000 2008

Hair Loss Types with their Treatments - American Chronicle
Steroid injections, creams, and shampoos (such as clobetasol or fluocinonide) for the scalp have been used for many years. ...
Fri Feb 22 12:40:55 +0000 2008

Medicis to Present At Roth Capital Partners Conference - Primenewswire (press release)
all 6 news articles
Fri Feb 15 08:05:27 +0000 2008

Fluocinonide Chemical Information

fluocinonide - A synthetic glucocorticoid and derivative of fluocinolone acetonide with anti-inflammatory and antipruritic activity. Fluocinonide binds the glucocorticoid receptor, followed by translocation of the ligand-receptor complex to the nucleus and transcription activation of genes containing glucocorticoid-responsive elements. Lipocortin-1 is one factor induced by fluocinonide that interacts and inhibits cytosolic phospholipase 2 alpha, thereby preventing phospholipase translocation to the perinuclear membrane and subsequent release and conversion of arachidonic acid to inflammatory prostaglandins. In addition, MAPK phosphatase 1 is induced, thereby preventing the triggering of the MAPK cascade resulting in pro-inflammatory effects via Jun N-terminal kinase and c-Jun. Finally, fluocinonide binds to and inhibits nuclear factor kappa-B directly, resulting in inhibition of cyclooxygenase 2 transcription and subsequent prostaglandin synthesis.


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