Fluticasone Propionate Information

What's inside Fluticasone Propionate

Fluticasone Propionate in the News

CASTLE Study Showed Similar Efficacy Between Once-Daily REYATAZ(R ... - CNNMoney.com
... Advair(R) (fluticasone propionate and salmeterol inhalation powder), Flonase(R) (fluticasone propionate), or Flovent(R) (fluticasone propionate). ...
Wed Feb 06 18:17:04 -0500 2008

Hillenbrand Files Amended Form-10 For Separation Of Hill-Rom ... - RTT News
The company would begin immediate shipment of fluticasone propionate nasal spray. The company's fluticasone propionate nasal spray is the AB-rated generic ...
Wed Jan 16 12:45:42 -0500 2008

Hi-Tech Gets FDA OK for Generic Flonase - Forbes
The FDA approved Hi-Tech's abbreviated new drug application for fluticasone propionate nasal spray, Flonase, at 50 micrograms. Hi-Tech said it will begin ...
Wed Jan 16 15:07:18 -0500 2008

Fluticasone Propionate Chemical Information

fluticasone propionate - The propionate salt form of fluticasone, a synthetic trifluorinated glucocorticoid receptor agonist with antiallergic, antiinflammatory and antipruritic effects. Binding and activation of the glucocorticoid receptor results in the activation of lipocortin that in turn inhibits cytosolic phospholipase A2, which triggers cascade of reactions involved in synthesis of inflammatory mediators, such as prostaglandins and leukotrienes. Secondly, mitogen-activated protein kinase (MAPK) phosphatase 1 is induced, thereby leads to dephosphorylation and inactivation of Jun N-terminal kinase directly inhibiting c-Jun mediated transcription. Finally, transcriptional activity of nuclear factor (NF)-kappa-B is blocked, thereby inhibits the transcription of cyclooxygenase 2, which is essential for prostaglandin production.