Head & Shoulders Information

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Head & Shoulders in the News

Flint Generals fire Kevin Kerr as head coach - MLive.com
Kevin Kerr has been fired as coach of the Flint Generals with 18 games remaining on the club's International Hockey League schedule. ...
Mon Mar 10 16:40:39 -0400 2008

AOL names Lynda Clarizio head of ad unit - CNNMoney.com
NEW YORK (AP) - AOL said Monday it has named Lynda Clarizio as the president of its emerging Platform A advertising unit, replacing Curt Viebranz. ...
Mon Mar 10 17:02:10 -0400 2008

Australian musos head to Texas - The Age
REM, the Breeders and Van Morrison head an outstanding list of veteran performers hoping to use the event to re-establish some cred and hawk forthcoming new ...
Mon Mar 10 15:02:23 -0400 2008

Head & Shoulders Chemical Information

pyrithione zinc - An organometallic compound and a derivative of the naturally occurring antibiotic aspergillic acid with antimicrobial, antifungal and anti-seborrheic effects. Although the mechanism of action has not been fully elucidated, pyrithione zinc maybe entering the cell in its chelate from, dissociating in the cytoplasm and exerting its anti-proliferative effect possibly through interaction with DNA. Alternatively, pyrithione might act by chelating metal cofactors of enzymes through its sulfhydryl group. Pyrithione has also been shown to interfere with thymidine uptake and may act as an antimetabolite for nicotinic acid or vitamin B6. Finally, pyrithione may act as a general transport inhibitor through weak-acid-induced cytosolic acidification and hence partial dissipation of the transmembrane proton motive force (PMF) on which the transport of many organic and inorganic solutes is reliant.