Hydrochlorothiazide-Lisinopril Information

Hydrochlorothiazide-Lisinopril

Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.

Lisinopril is in a group of drugs called ACE inhibitors. ACE stands for angiotensin converting enzyme. Lisinopril lowers blood pressure and also relieves symptoms of fluid retention.

The combination of hydrochlorothiazide and lisinopril is used to treat hypertension (high blood pressure).

Hydrochlorothiazide and lisinopril may also be used for other purposes not listed in this medication guide.

Do not use this medication if you are unable to urinate.
You should not use this medication if you are allergic to any other ACE inhibitor, such as benazepril (Lotensin), captopril (Capoten), fosinopril (Monopril), enalapril (Vasotec), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), or trandolapril (Mavik).

Before taking hydrochlorothiazide and lisinopril, tell your doctor if you have kidney disease (or are on dialysis), liver disease, congestive heart failure, gout, lupus, diabetes, or an allergy to sulfa drugs.

Lisinopril can cause birth defects in the baby if you take the medication during pregnancy. Do not use hydrochlorothiazide and lisinopril without telling your doctor if you are pregnant or planning a pregnancy. Avoid the regular use of salt substitutes in your diet, and do not take potassium supplements while taking hydrochlorothiazide and lisinopril, unless your doctor has told you to.

Some things can cause your blood pressure to get too low. This includes vomiting, diarrhea, heavy sweating, heart disease, dialysis, a low-salt diet, or taking other diuretics (water pills). Follow your doctor's instructions about the type and amount of liquids you should drink while taking hydrochlorothiazide and lisinopril. Tell your doctor if you have a prolonged illness that causes diarrhea or vomiting.

What's inside Hydrochlorothiazide-Lisinopril

Recent Hydrochlorothiazide-Lisinopril Side Effects

Posted by skane2009 18 days ago
I thought this drug was a lifesaver.. I was diagnosed with Type II diabetes in 2003. By 2005, I had an enlarged heart and high blood pressure. I was given 10/12.5 originally. After a few months, my echocardigram showed that my heart was normal size again. I was also told that Lisinopril-HCTZ will protect my kidneys. So, naturally I this drug was a lifesaver to me. Since that time, weird things have been occurring and when I mention them to my doctor's (and I have had several) they all chalk it up to panic disorder related issues. I gave them the benefit of the doubt because truth be told, I DO suffer from anixiety disorders and have since I was 19. (I am 40 now) ... But the more I read and research others having similar side effects, the more I wonder if it is all "in my head" or a direct cause of this drug. Over the last 2 years or so, my dosage was increased. I now take 20/25 once a day. I also take Glucovance 500/2.5 twice a day for diabetes. My main symptoms that I suffer from are: severe dizziness, faintness, increased anxiety and phobias, depersonalization (feeling like I am not "here", facial flushing and hot flashes, constant throat clearing, nasal congestion, insomnia, total lack of sex drive, irritability, itchy skin, palpitations, mysterious aches and pains, brain fog and memory issues, and probably a few I can't recall right now. The dizziness, panic, and facial flushing are every day occurrences for me. My face looks red and gets extremely hot to the touch as well. I have to keep checking my temp to make sure I don't have a fever.The dizziness is so bad that I need help sometimes when I walk because it feels like I am off balance or like I am going to pass out. I have had several heart monitors, EKG's, 3-D echo's, blood tests, and even a brain MRI to rule out other things. Please, anyone.. give me some advice. I am so scared. I feel like I am dying but can't get a doctor to listen to me. Is it really possible that this drug can actually cause all these terrible symptoms?

Posted by citygurl about 1 month ago
I started taking Lisinopril 2 weeks ago. I was unaware of any problems until I started having increased heart rate and rise in blood pressure when I went to physical therapy, My pulse was 120 and bp was 150/100 had to get daughter to come pick me up. I Could not drive home. Prior to this I would wake up every morning and my heart would be pounding and racing. O.k. I thought it was anxiety but I don't usually get this way over nothing. I also take hctz 25mgs and only 10mgs of Lisinopril. This is the other symptoms; blurred vision, dry cough, night sweats, nightmares(vivid) post nasal drip and feeling like there is a wad of something in my throat and I can't swallow it. Hot flashes and dizziness. I have been off Lisinopril for 2 days and hopefully I haven't taken it long enough to do any more damage. Oh I forgotI had a crushing headache on the left side of my head. I am so glad I found this post and I know that I am not alone.We should all do our homework and investigate our medicines before we put them in our mouth. Lord knows the doctors are not going to tell us and neither are the pharmacists.

Posted by blessings09 3 months ago
dry cough .heart pounding, /skipping beat ,. weepy ,.also tiredness when walking the same distance i usually wal, before taking this medication..

Hydrochlorothiazide-Lisinopril Chemical Information

hydrochlorothiazide - The hydrogenated derivative of chlorothiazide, a thiazide diuretic with antihypertensive and anti-urolithic effects. This agent binds to the electroneutral Na-K-Cl cotransporter (NKCC) and thereby impairs Na+, K+ and Cl- reabsorption on the luminal membrane of the early segment in the distal convoluted tubule in the kidney. This leads to an increase in urinary excretion of sodium, chloride, potassium, bicarbonate and water subsequently reducing plasma and extracellular fluid volume leading to a reduction in blood pressure. Hydrochlorothiazide also decreases urinary calcium and uric acid excretion by direct action on the distal tubule.

lisinopril - A synthetic peptide derivate and long-acting angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Lisinopril specifically and competitively inhibits angiotensin-converting enzyme thereby decreasing the formation of the potent vasoconstrictor angiotensin II. This leads to a diminished vasopressor activity. In addition, angiotensin II-stimulated aldosterone secretion by adrenal cortex is decreased which results in a decrease of sodium and water retention and an increase of serum potassium.