Hydrocortisone Acetate-Lidocaine Hydrochloride Information
What's inside Hydrocortisone Acetate-Lidocaine Hydrochloride
Hydrocortisone Acetate-Lidocaine Hydrochloride Active Ingredients: hydrocortisone acetate, lidocaine hydrochloride, details.| Hydrocortisone Acetate-Lidocaine Hydrochloride Dosages & Strengths | ||||
|---|---|---|---|---|
| Strength | Format | Route | Strength | Class |
| Hydrocortisone Acetate-Lidocaine Hydrochloride 0.5%-3% | lotion | topical | 100.0 milliliter(s) | OTC |
| Hydrocortisone Acetate-Lidocaine Hydrochloride 0.5%-3% | cream | topical | 100.0 gram(s) | OTC |
| Hydrocortisone Acetate-Lidocaine Hydrochloride 0.5%-3% | cream | topical | 100.0 gram(s) | OTC |
| Hydrocortisone Acetate-Lidocaine Hydrochloride 1%-3% | kit | rectal | 100.0 gram(s) | OTC |
| Hydrocortisone Acetate-Lidocaine Hydrochloride 1%-3% | kit | rectal | 100.0 gram(s) | OTC |
| Hydrocortisone Acetate-Lidocaine Hydrochloride 0.5%-3% | kit | rectal | 100.0 gram(s) | OTC |
| Hydrocortisone Acetate-Lidocaine Hydrochloride 0.5%-3% | cream with applicator | rectal | 100.0 gram(s) | OTC |
| Hydrocortisone Acetate-Lidocaine Hydrochloride 0.5%-3% | cream with applicator | rectal | 100.0 gram(s) | OTC |
Hydrocortisone Acetate-Lidocaine Hydrochloride Chemical Information
hydrocortisone acetate - The synthetic acetate salt form of hydrocortisone, a corticosteroid with anti-inflammatory and immunosuppressive properties. Hydrocortisone acetate initially binds to the cytoplasmic glucocorticoid receptor; then the receptor-ligand complex is translocated to the nucleus where it initiates the transcription of genes encoding for anti-inflammatory mediators, such as cytokines and lipocortins. Lipocortins inhibit phospholipase A2, thereby blocking the release of arachidonic acid from membrane phospholipids and preventing the synthesis of prostaglandins and leukotrienes.
lidocaine hydrochloride - The hydrochloride salt from of lidocaine, an aminoethylamide and a prototypical member of the amide class anesthetics. Lidocaine interacts with voltage-gated Na+ channels in the nerve cell membrane and blocks the transient increase in permeability of excitable membranes to Na+. This prevents the generation and conduction of nerve impulses and produces a reversible loss of sensation. Lidocaine hydrochloride also exhibits class IB antiarrhythmic effects. The agent decreases the flow of sodium ions into myocardial tissue, especially on the Purkinje network, during phase 0 of the action potential, thereby decreasing depolarization, automaticity and excitability.
Hydrocortisone Acetate-Lidocaine Hydrochloride RSS Feed