| Hydrocortisone Acetate-Pramoxine HCl Dosages & Strengths | ||||
|---|---|---|---|---|
| Strength | Format | Route | Strength | Class |
| Hydrocortisone Acetate-Pramoxine HCl 1%-1% | cream | topical | 100.0 gram(s) | OTC |
| Hydrocortisone Acetate-Pramoxine HCl 2.5%-1% | cream | topical | 100.0 gram(s) | OTC |
| Hydrocortisone Acetate-Pramoxine HCl 2.5%-1% | cream with applicator | rectal | 100.0 gram(s) | OTC |
| Hydrocortisone Acetate-Pramoxine HCl 1%-1% | foam | rectal | 100.0 gram(s) | OTC |
hydrocortisone acetate - The synthetic acetate salt form of hydrocortisone, a corticosteroid with anti-inflammatory and immunosuppressive properties. Hydrocortisone acetate initially binds to the cytoplasmic glucocorticoid receptor; then the receptor-ligand complex is translocated to the nucleus where it initiates the transcription of genes encoding for anti-inflammatory mediators, such as cytokines and lipocortins. Lipocortins inhibit phospholipase A2, thereby blocking the release of arachidonic acid from membrane phospholipids and preventing the synthesis of prostaglandins and leukotrienes.
pramoxine