Imitrex Nasal Information

What's inside Imitrex Nasal

Imitrex Nasal in the News

Understanding migraines - Kansas.com
Triptans, such as Imitrex, are used by many people. DHE nasal spray often provides quick relief, Leu says. Edwards has tried nearly everything through the ...
Tue Jan 22 02:04:07 -0500 2008

Nasal Spray May Ease Cluster Headaches - CBS News
They point out that the only drug currently approved by the FDA to treat cluster headaches is injectable Imitrex, which is also used to treat migraines.
Tue Aug 28 16:51:37 -0400 2007

Trexima(TM) (Sumatriptan/Naproxen Sodium) Demonstrated Migraine ... - PR Newswire (press release)
About Imitrex(R) (sumatriptan succinate) Tablets Imitrex is a prescription medication indicated for the acute treatment of migraine in adults. ...
Fri Jun 08 09:37:58 -0400 2007

Imitrex Nasal Chemical Information

sumatriptan succinate - The succinate salt form of sumatriptan, a member of the triptan class of compounds with anti-migraine property. Sumatriptan succinate selectively binds to and activates serotonin 5-HT1 receptors. This results in constriction of meningeal, dural, cerebral or pial blood vessels via stimulation of the 5-HT1B receptors, thereby reducing the vascular pulsation and may provide relief in migraine headaches. Furthermore, agonistic action of this agent through presynaptic stimulation of 5-HT1D and/or 5-HT1F receptors prevents release of vasoactive and pro-inflammatory neuropeptide (calcitonin gene-related peptide), thereby may also relieve migraine headaches. In addition, central inhibition of pain transmission via the inhibition of trigeminal neurons in the brain stems and upper spinal cord mediated by 5-HT1B, 5-HT1D or 5-HT 1F receptors also aides in the alleviation of migraine pain