Imuran Information
What's inside Imuran
Imuran Active Ingredients: azathioprine sodium, azathioprine, details.| Imuran Dosages & Strengths | ||||
|---|---|---|---|---|
| Strength | Format | Route | Strength | Class |
| Imuran 50 mg | tablet | oral | 1.0 each | OTC |
| Imuran 100 mg | powder for injection | intravenous | 1.0 each | OTC |
Recent Imuran Side Effects
Posted by iamfire 8 months ago
closing throat, sweats, swollen glands, no menstrual period, leg pain, severe headaches, chest pain. I have been taking 100 ...
Posted by joe_2008 about 1 year ago
I took Imuran for 3 weeks....150mg/day....started week one with only 50mgs/day, week 2 100mg and then in week 3 got up to the...
Posted by navycross about 1 year ago
Shortness of breath has continued to worsen as its built up in my system. Chest pain and back pain on my left side seem to be...
Imuran in the News
Kidneys Affected In 40 Percent Of People With Lupus - Medical News Today (press release)
Immunosuppressive drugs may also be used (with or in place of steroid treatments), such as cyclophosphamide (Cytoxan®), azathioprine (Imuran®), ...
Thu Mar 06 04:08:24 -0500 2008
Reverse treatment aids Crohn's sufferers - Globe and Mail
... are published today but similar in nature - Ms. Price began taking azathioprine (brand name Imuran) and Remicade after only three weeks on steroids. ...
Fri Feb 22 11:23:28 -0500 2008
Aggressive Therapy for Crohn's Disease Produces Better Outcomes - Lex 18
Sixty-seven patients assigned to combined immunosuppression received three infusions of Remicade (infliximab) with Imuran (azathioprine) at the start, ...
Fri Feb 22 17:46:12 -0500 2008
Imuran Chemical Information
azathioprine sodium - The sodium salt form of azathioprine, a pro-drug of purine analogue with immunosuppressive activity. Azathioprine is converted in vivo to its active metabolite 6-mercaptopurine (6-MP), which substitutes for the normal nucleoside and mistakenly gets incorporated into DNA sequences. This leads to inhibition of DNA, RNA, and protein synthesis. As a result, cell proliferation may be inhibited, particularly in lymphocytes and leukocytes.
azathioprine - A purine analogue with cytotoxic and immunosuppressive activity. Azathioprine is a prodrug that is converted by hepatic xanthine oxidase to its active metabolite 6-mercaptopurine (6-MP). 6-MP is further metabolized by hypoxanthine-guanine phosphoribosyltransferase (HGPRT) into 6-thioguanosine-5'-phosphate (6-thio-GMP) and 6-thioinosine monophosphate (6-thio-IMP), both inhibit nucleotide conversions and de novo purine synthesis. This leads to inhibition of DNA, RNA, and protein synthesis. As a result, cell proliferation may be inhibited, particularly in lymphocytes and leukocytes.
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