Lactulose (IPA: ˈlæktjʊləʊz) is a synthetic sugar used in the treatment of constipation[1] and hepatic encephalopathy, a complication of liver disease. It is a disaccharide (double-sugar) formed from one molecule each of the simple sugars (monosaccharides) fructose and galactose. The commercial syrup used for treatment of constipation is dyed yellow-orange. It is produced commercially by isomerization of lactose.
In the treatment of chronic constipation, the metabolites of lactulose draw water into the bowel, causing a cathartic effect through osmotic action. Unlike other laxatives that are recommended for temporary relief, lactulose can be taken daily for decades. It is safe for people of all ages, except for those in a very small percentage of the population that are galactose intolerant. Dosage may have to be adjusted over time to produce the desired effect because the laxative effect can reduce somewhat with daily treatment.
| Lactulose Dosages & Strengths | ||||
|---|---|---|---|---|
| Strength | Format | Route | Strength | Class |
| Lactulose - | solution | compounding | 100.0 milliliter(s) | OTC |
| Lactulose 10 g/15 mL | syrup | oral | 15.0 milliliter(s) | OTC |
Posted by grgalva over 2 years ago
Can turn stool red and very irirtated (painful)
Is there any solution for this?
Maybe somethig to numb the pain a little like an oragel(ambesol) that is used for tooth ache
Posted by lizz8 over 4 years ago
Doctor prescribed it for me, as a laxative. It gave me horrible gas and bloating. Had to stop using it.
Posted by rbudzilek over 7 years ago
mental confusion, weakness
Kristalose(R) Offers Prescription Alternative to MiraLAX(R) and ... - Earthtimes
Kristalose(R) (lactulose) for Oral Solution is a proprietary prescription laxative and the brand name for a unique crystalline form of lactulose that treats ...
Tue Feb 26 14:55:52 +0000 2008
Wants answers: Jason Bunting with daughter Megan DAVID HOLLINS - News & Star
She noticed that the prescribed dose of lactulose solution – between 10 and 20 millilitres, twice a day – was very high for a two-year-old. ...
Wed Feb 20 07:13:07 +0000 2008
What Causes Portal Hypertension? - TamilStar.com
The drug lactulose can help treat confusion and other mental changes associated with encephalopathy. Maintaining good nutritional habits and keeping a ...
Fri Feb 08 09:48:53 +0000 2008
lactulose - A disaccharide (sugar) synthesized from fructose and galactose, Lactulose is used to treat constipation and some liver diseases. Nondigestible in mammals, lactulose passes unabsorbed down to the large intestine where resident bacteria consume it and produce lactic, acetic, and formic acids, which draw fluid into the bowel to soften the stool (laxative effect). Acidification of the colon contents attracts ammonia from the bloodstream, assisting stool excretion; helpful in liver failure when ammonia cannot be detoxified. (NCI04)