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Lidex Information

What's inside Lidex

Lidex Active Ingredients: fluocinonide, details.
Lidex Dosages & Strengths
Strength Format Route Strength Class
Lidex 0.05% solution topical 100.0 milliliter(s) OTC
Lidex 0.05% ointment topical 100.0 gram(s) OTC
Lidex 0.05% cream topical 100.0 gram(s) OTC
Lidex 0.05% gel topical 100.0 gram(s) OTC

Recent Lidex Side Effects

Posted by lizz8 over 4 years ago
My family doctor gave this to me, to heal sores inside my mouth. The medication I got is Lidex gel. It does heal canker sor...


Lidex in the News

Medicis Reports Fourth Quarter and Year End 2007 Financial Results - Primenewswire (press release)
... SOLODYN(R) (minocycline HCl, USP) Extended Release Tablets, TRIAZ(R) (benzoyl peroxide), LIDEX(R) (fluocinonide) Cream, 0.05%, VANOS(R) (fluocinonide) ...
Wed Feb 27 16:13:32 -0500 2008

Medicis and Revance Announce Strategic Collaboration - CNNMoney.com
... TRIAZ(R) (benzoyl peroxide), LIDEX(R) (fluocinonide) Cream, 0.05%, VANOS(R) (fluocinonide) Cream, 0.1%, SYNALAR(R) (fluocinolone acetonide), ...
Tue Dec 11 16:52:51 -0500 2007

Medicis to Present At RBC Capital Markets Healthcare Conference - CNNMoney.com
... TRIAZ(R) (benzoyl peroxide), LIDEX(R) (fluocinonide) Cream, 0.05%, VANOS(R) (fluocinonide) Cream, 0.1%, SYNALAR(R) (fluocinolone acetonide), ...
Mon Dec 10 08:07:12 -0500 2007


Lidex Chemical Information

fluocinonide - A synthetic glucocorticoid and derivative of fluocinolone acetonide with anti-inflammatory and antipruritic activity. Fluocinonide binds the glucocorticoid receptor, followed by translocation of the ligand-receptor complex to the nucleus and transcription activation of genes containing glucocorticoid-responsive elements. Lipocortin-1 is one factor induced by fluocinonide that interacts and inhibits cytosolic phospholipase 2 alpha, thereby preventing phospholipase translocation to the perinuclear membrane and subsequent release and conversion of arachidonic acid to inflammatory prostaglandins. In addition, MAPK phosphatase 1 is induced, thereby preventing the triggering of the MAPK cascade resulting in pro-inflammatory effects via Jun N-terminal kinase and c-Jun. Finally, fluocinonide binds to and inhibits nuclear factor kappa-B directly, resulting in inhibition of cyclooxygenase 2 transcription and subsequent prostaglandin synthesis.



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