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Lipitor Information

What's inside Lipitor

Lipitor Active Ingredients: atorvastatin, details.
Lipitor Dosages & Strengths
Strength Format Route Strength Class
Lipitor 10 mg tablet oral 1.0 each OTC
Lipitor 20 mg tablet oral 1.0 each OTC
Lipitor 40 mg tablet oral 1.0 each OTC
Lipitor 80 mg tablet oral 1.0 each OTC

Recent Lipitor Side Effects

Posted by drybone8 about 5 hours ago
I am a 37 year old man who weighed approximately 188lbs when I prescribed 20mg of Lipitor and fish oil to combat my high trig...

Posted by denne 6 days ago
I started taking Lipitor in April 2009 and my Dr prescribed 10 mg per day. As I usually have negative reactions to medicatio...

Posted by eml256 9 days ago
2 genetic mutations in the gene that encodes for the transporter protein responsible for moving anti cholesterol statin drugs...


Lipitor in the News

Pfizer: Outsourcing is necessary business - Therapeutics Daily (subscription) (press release)
Basically, he?s saying, get used to it. Pfizer is preparing for the loss of its patent protection on the world?s top-selling drug, Lipitor. The ...
Sun Mar 09 13:28:34 -0400 2008

Pfizer outlines plans to face life after Lipitor to analysts - Pharma Times (subscription)
... are still unsure whther the firm has the means to deal with the patent loss it will face on the cholesterol blockbuster Lipitor (atorvastatin) in 2010. ...
Thu Mar 06 05:52:35 -0500 2008

Pfizer steels itself for Lipitor expiry - Financial Times
... structure would prepare it for the impending expiry of the patent for its blockbuster cholesterol drug Lipitor, worth some $12bn in annual sales. ...
Wed Mar 05 20:53:59 -0500 2008


Lipitor Chemical Information

atorvastatin - The calcium salt form of atorvastatin, a synthetic lipid-lowering agent. Atorvastatin competitively inhibits hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, the enzyme which catalyzes the conversion of HMG-CoA to mevalonate, a key step in cholesterol synthesis. Atorvastatin also increases the number of LDL receptors on hepatic cell surfaces to enhance uptake and catabolism of LDL and reduces LDL production and the number of LDL particles. This agent lowers plasma cholesterol and lipoprotein levels and modulates immune responses by suppressing MHC II (major histocompatibility complex II) on interferon gamma-stimulated, antigen-presenting cells such as human vascular endothelial cells. (NCI04)




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