Lipitor Information

Lipitor

Lipitor is a cholesterol-lowering medication that blocks the production of cholesterol (a type of fat) in the body.

Lipitor reduces low-density lipoprotein (LDL) cholesterol and total cholesterol in the blood. Lowering your cholesterol can help prevent heart disease and hardening of the arteries, conditions that can lead to heart attack, stroke, and vascular disease.

Lipitor is used to treat high cholesterol. Lipitor is also used to lower the risk of stroke, heart attack, or other heart complications in people with coronary heart disease or type 2 diabetes.

What's inside Lipitor

Recent Lipitor Side Effects

Posted by mavifox 1 day ago
I was extremely healthy all my life. After taking Lipitor for two months I started having an inexplicable pain in my lower back muscles. I didnt pay much attention but a month later the pain extended to my legs making difficult for me to walk. Also I have a stiff neck and the pain extends to my arms and back. My doctor thinks I have Fibromyalgia and Arthritis but I think I am suffering the side effects of Lipitor. I stopped taking Lipitor a month ago and the pain is still preventing me to move. Is it ever going to go away?

Posted by antje 4 days ago
I have been on lipitor now for two weeks. I am very tired in the late afternoons and cannot wait to get to bed. I am now starting with bad moods. Had severe diaree yesterday.

Posted by paensmin 5 days ago
I'm a 47 year old male, with no medical problems except high colersterol. I took lipitor for a few months. After the first month, I noticed the general weekness in my legs and stiffining of my achilies tendon. By the third month, these problems continued to worsen. My achilies tendon would be so tight, I had to stretch my foot for a few minutes before getting up in the morning. Then, after getting up, I'd walk like Frankinstein for awhile. My achillies tendon was sore all day, and my legs were weak. My legs felt like there wasn't any blood or strenght in them; I felt like an old man who's leg were atrophing. Anyway, I was playing tennis one night, and a friend noticed I wasn't moving. My wife remarked that I was on Lipitor, and we think it's hurting my legs. This friend knew of several people, including his father, that had experience the exact same problem. I quit taking Lipitor that very day. Since then, I've talked with others, and many have had this same side affect. Please note, two guys in my office are taking Lipitor with no problem, so, it not universal. However, I believe it more common that the medical establishment is reveling. From what I've briefly read, Lipitor block the production cholesterol, but also blocks the production of CoQ10, dolichols and other vital liver biochemicals needed for healthy muscels and tendons. I've been off Lipitor for a couple months, and my legs and achilies tendon are good. Not a 100%, but good. I still experience moderate stiffness in my achilies tendon the morning after playing tennis and very stight stiffness otherwise. During the day, my achilies tendon feels fairly normal, and my leg strengh feels normal. I'm not a hypochondriac; however, I have no doubt, this drug is dangerous and causes muscle and tendon stiffness and damage.

Lipitor in the News

Inventor of Lipitor to speak in Chico - Red Bluff Daily News
Inventor of Lipitor to speak in ChicoRed Bluff Daily NewsSynthetic organic chemist Bruce Roth, Ph.D., who synthesized the compound that would eventually be marketed as Lipitor as a researcher for Warner- ...
Fri Jan 29 15:05:18 +0000 2010

Drug counterfeiter gets 9 years - Sun-Sentinel
Drug counterfeiter gets 9 yearsSun-Sentinel... with selling adulterated cancer, HIV and other drugs into mainstream pharmacy supplies, including $42 million worth of bogus cholesterol drug Lipitor. ...
Fri Feb 05 23:11:00 +0000 2010

France loses edge, Pfizer gets the goods - GulfNews
TopNews United StatesFrance loses edge, Pfizer gets the goodsGulfNewsPfizer's somewhat disappointing new guidance for revenue in 2012, the year after its blockbuster cholesterol drug Lipitor loses exclusivity, puts a renewed ...Pfizer Q4 Profit Misses EstimatesTopNews United StatesPfizer profits soar but analysts unhappy about 2010 estimatesPharma Timesall 4 news articles »
Thu Feb 04 21:29:54 +0000 2010

Lipitor Chemical Information

atorvastatin - The calcium salt form of atorvastatin, a synthetic lipid-lowering agent. Atorvastatin competitively inhibits hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, the enzyme which catalyzes the conversion of HMG-CoA to mevalonate, a key step in cholesterol synthesis. Atorvastatin also increases the number of LDL receptors on hepatic cell surfaces to enhance uptake and catabolism of LDL and reduces LDL production and the number of LDL particles. This agent lowers plasma cholesterol and lipoprotein levels and modulates immune responses by suppressing MHC II (major histocompatibility complex II) on interferon gamma-stimulated, antigen-presenting cells such as human vascular endothelial cells. (NCI04)