Lotrel Information

Lotrel

Amlodipine is in a group of drugs called calcium channel blockers. Amlodipine relaxes (widens) blood vessels and improves blood flow. Benazepril is in a group of drugs called ACE inhibitors. ACE stands for angiotensin converting enzyme. Benazepril also widens blood vessels and also prevents the body from retaining water. Amlodipine and benazepril is used to treat high blood pressure (hypertension). It is usually given after other blood pressure medications have been tried without successful treatment. Amlodipine and benazepril may also be used for other purposes not listed in this medication guide. Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results from this medication. Take each dose with a full glass of water. Amlodipine and benazepril can be taken with or without food. Vomiting, diarrhea, or heavy sweating can cause you to become dehydrated. This can lead to very low blood pressure, electrolyte disorders, or kidney failure while you are taking amlodipine and benazepril. Drink 6 to 8 full glasses of water daily while you are taking this medication. To be sure this medication is helping your condition; your blood pressure will need to be checked on a regular basis. Your kidney or liver function may also need to be tested.

What's inside Lotrel

Recent Lotrel Side Effects

Posted by jflip1960 29 days ago
I have been on Lotrel for about 2 years and I have not been getting some of the severe side effects mention BUT, frequent urination, low sex drive, minor memory loss, cramping, just to name a few. I was taking Lotrel along with Tekturna and receiving excellent results. However, I'm a active person and I have noticed when I run long distance, I'm getting cramps now. I'm going to ask my doctor to tray Ace Inhibitors for me.

Posted by teets77351 about 1 month ago
I was Taking Lotrel 10/20 For 6 Years For My High Blood Pressure About 7 Months Ago The Doctor Changed Me To Loterl 10/40 In 2009 Because Of My Blood Pressuer Going Higher. And Then I Started Hurting In My Shoulders And Numbness In My Legs stomach pain pounding heart Rate Pain In My Ribs Lower Back Pain Ringing In My Right Ear. Then I Went To The Hospital To Have Tests Done On My Urine From Hurting In My Ribs And I Got Blood Test Done And It Showed That My Blood Sugar Was 360 It Has Never Been That High Taking Lotrel 10/20 For 6 Years. Now I Am On Blood Glucose Meds And The Meds Is Not Working. My Blood Glucose Is Still 360. I Am Getting Off Of This Lotrel 10/40. And Going To A Different High Blood Pressure Medication.

Posted by jzapata23 4 months ago
One week into taking the meds . I did feel anxiety and nervousness. I have never felt those feeling until I have taken that medicine. i also had diarrhea.I started feeling a sensation above my knee where is would start tingling and it would go numb and then start burning after standing for like 10 mins .I have never had any problems with my legs. Then the second week into in the middle of my thigh started a burning sensation. The third week it just kept getting worse . I went back to my doc and told him he said it was my weight and me walking. So Sept 11,09 I stop taking it. I have been off it for like a 7days . the burning has gone down to a soreness in my right leg but my right foot is very sensitive. It very annoying. I do not what it did to me . It has been the worse 1 month experience in my life. I have lost 25 pounds which is great eating right and walking.If it was not for this website and my mother in law I would of kept taking it. Like a dummy. I am looking for a good doctor in

Lotrel in the News

Teva's Needle-Free Tjet(R) Device Takes a Kid-Friendly Approach to Growth ... - PR-CANADA.net (press release)
Teva's Needle-Free Tjet(R) Device Takes a Kid-Friendly Approach to Growth ...PR-CANADA.net (press release)... including that relating to the generic versions of Neurontin®, Lotrel® and Protonix®, the current economic conditions, competition from brand -name ...and more »
Sat Feb 06 19:56:15 +0000 2010

高血压复方药物制剂受宠 产品出新不断 - 药通天下网
高血压复方药物制剂受宠 产品出新不断药通天下网目前全球的复方制剂主要有4种类型，分别为ACEI与CCB复方制剂，包括贝那普利/氨氯地平（Lotrel）、群多普利+维拉帕米（Tarka）、雷米普利+非洛地平（Unimax）；ACEI与 ...and more »
Mon Jan 25 02:31:31 +0000 2010

Teva Announces Settlement in Principle regarding Certain Drug Pricing Lawsuits - American Chronicle
Teva Announces Settlement in Principle regarding Certain Drug Pricing LawsuitsAmerican Chronicle... including that relating to the generic versions of Neurontin®, Lotrel®, Protonix® and Eloxatin®, the current economic conditions, competition from ...
Fri Feb 05 14:58:03 +0000 2010

Lotrel Chemical Information

amlodipine besylate - The besylate salt of amlodipine, a synthetic, dihydropyridine, calcium channel blocker with antihypertensive and antianginal effects. Amlodipine inhibits the influx of extracellular calcium ions into myocardial and peripheral vascular smooth muscle cells, thereby preventing vascular and myocardial contraction. This results in a dilatation of the main coronary and systemic arteries,decreases myocardial contractility, increases blood flow and oxygen delivery to the myocardial tissue and decreases total peripheral resistance. This agent may also modulate multi-drug response (MDR) activity through inhibition of the p-glycoprotein efflux pump.

benazepril hydrochloride - Thy hydrochloride salt of a dicarbocyl-containing peptide and angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. As a prodrug, benazepril hydrochloride is metabolized to its active form benazeprilat. Benazeprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. Benazepril hydrochloride also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow.