Minizide Information
What's inside Minizide
Minizide Active Ingredients: polythiazide, prazosin hydrochloride, details.| Minizide Dosages & Strengths | ||||
|---|---|---|---|---|
| Strength | Format | Route | Strength | Class |
| Minizide 0.5 mg-5 mg | capsule | oral | 1.0 each | OTC |
| Minizide 0.5 mg-2 mg | capsule | oral | 1.0 each | OTC |
| Minizide 0.5 mg-1 mg | capsule | oral | 1.0 each | OTC |
| Minizide 0.5 mg-5 mg | capsule | oral | 1.0 each | OTC |
Minizide Chemical Information
polythiazide - A sulfonamide derivative and a synthetic thiazide with diuretic, antihypertensive and anti-urolithic properties. By blocking the Na/Cl transporter, polythiazide inhibits reabsorption of sodium and chloride in the proximal and distal convoluted tubule of the kidney, resulting in increased excretion of water and electrolytes (sodium, potassium, chloride, magnesium, and bicarbonate) and subsequent reversal of hypertension. In addition, this agent exerts its anti-urolithic effect by decreasing calcium and uric acid excretion.
prazosin hydrochloride - A synthetic piperazine derivative with hypotensive antiadrenergic properties, Prazosin Hydrochloride reduces peripheral resistance and relaxes vascular smooth muscles as a selective adrenergic alpha-1 antagonist by a mechanism not completely known. It is used in the treatment of heart failure, hypertension, pheochromocytoma, Raynaud's syndrome, prostatic hypertrophy, and urinary retention. (NCI04)
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