Naphazoline HCl-Pheniramine Maleate Information

What's inside Naphazoline HCl-Pheniramine Maleate

Recent Naphazoline HCl-Pheniramine Maleate Side Effects

Posted by kheitman about 1 year ago
I noticed that my eyes are addicted in the way that if I do not use them, my eyes are very red. I have to use them.

Posted by theevil545 over 2 years ago
addiction I can't sleep without using this drug but as nasal spray

Naphazoline HCl-Pheniramine Maleate Chemical Information

naphazoline hydrochloride - The hydrochloride salt form of naphazoline, an imidazole derivative and a direct-acting sympathomimetic amine with vasoconstrictive properties. Upon ocular administration, naphazoline hydrochloride exerts its effect by acting on alpha-adrenergic receptors in the arterioles of the conjunctiva to produce vasoconstriction, resulting in decreased conjunctival congestion and diminished itching, irritation and redness.

pheniramine maleate - The maleate salt form of pheniramine, an alkylamine derivative with antihistaminic and vasodilatory properties. Pheniramine maleate binds to histamine H1 receptors, thereby inhibiting phospholipase A2 and production of endothelium-derived relaxing factor, nitric oxide. Subsequent lack of activation of guanylyl cyclase through nitric oxide results in decreased cyclic GMP (cGMP) levels, thereby inhibiting constriction of smooth muscle tissue, and decreased capillary permeability and histamine-activated allergic reactions.