| Ondansetron Hydrochloride Novaplus Dosages & Strengths | ||||
|---|---|---|---|---|
| Strength | Format | Route | Strength | Class |
| Ondansetron Hydrochloride Novaplus 2 mg/mL | solution | injectable | 1.0 milliliter(s) | OTC |
ondansetron hydrochloride - The hydrochloride salt of the racemic form of ondansetron, a carbazole derivative and a selective, competitive serotonin 5-HT3 receptor antagonist with antiemetic properties. Although its mechanism of action has not been fully characterized, ondansetron appears to competitively block the action of serotonin at 5HT3 receptors peripherally in the gastrointestinal tract as well as centrally in the area postrema of the CNS (the chemoreceptor trigger zone for vomiting), resulting in suppression of chemotherapy- and radiotherapy-induced nausea and vomiting.