Paxil Information

What's inside Paxil

Recent Paxil Side Effects

Posted by lisa44 about 1 month ago
I am a 44 year old woman and recently went to the ER for depression. I have lost both parents recently recently and have a v...

Posted by cam2121 about 1 month ago
I am a 21 year old female and just started taking paxil for anxiety & depression. My mother is on the same thing (heart probl...

Posted by wildflower99 3 months ago
I just started taking Paxil six days ago for severe anxiety, OCD and PTSD. Already, I have experienced dizziness, out-of-body...

Paxil in the News

Glaxo escapes prosecution on Seroxat disclosure - MarketWatch
Up to 8000 under-18s were taking Seroxat, called Paxil in the US, for depression, the regulator said. Laws have subsequently been changed to require ...
Thu Mar 06 06:13:48 -0500 2008

UK to Tighten Pharma Rules as Glaxo Avoids Prosecution - Wall Street Journal
GlaxoSmithKline won’t be prosecuted for its handling of safety data on the antidepressant Seroxat (sold in the US as Paxil), UK regulators have decided. ...
Thu Mar 06 08:49:28 -0500 2008

Britain won't charge Glaxo in Paxil risk - Philadelphia Inquirer
By Robert Barr AP LONDON - British regulators will not prosecute GlaxoSmithKline PLC for allegedly withholding data about an antidepressant that may have ...
Fri Mar 07 03:10:42 -0500 2008

Paxil Chemical Information

paroxetine hydrochloride - The hydrochloride salt form of paroxetine, a phenylpiperidine derivative and a selective serotonin reuptake inhibitor (SSRI) with antidepressant and anxiolytic properties. Paroxetine binds to the pre-synaptic serotonin transporter complex resulting in negative allosteric modulation of the complex thereby blocking reuptake of serotonin by the pre-synaptic transporter. Inhibition of serotonin recycling enhances serotonergic function through serotonin accumulation in the synaptic cleft, resulting in long-term desensitization and downregulation of 5HT1 (serotonin) receptors and leading to symptomatic relief of depressive illness.