Pyrithione Zinc Information

What's inside Pyrithione Zinc

Pyrithione Zinc in the News

Wash & Wear ... Shampoos and conditioners - Vancouver Sun
Describe it: This all-new formula still contains the active anti-dandruff ingredient, pyrithione zinc, but is now available with a separate conditioner. ...
Tue Mar 04 03:18:25 -0500 2008

Unilever Lathers Up - WJACtv.com
Although Clear contains zinc pyrithione, the same active ingredient as Head & Shoulders, Unilever claims its shampoo is more effective thanks to a patented ...
Wed Feb 20 05:04:54 -0500 2008

Unilever Lathers Up - KMBC.com
Although Clear contains zinc pyrithione, the same active ingredient as Head & Shoulders, Unilever claims its shampoo is more effective thanks to a patented ...
Wed Feb 20 05:17:01 -0500 2008

Pyrithione Zinc Chemical Information

pyrithione zinc - An organometallic compound and a derivative of the naturally occurring antibiotic aspergillic acid with antimicrobial, antifungal and anti-seborrheic effects. Although the mechanism of action has not been fully elucidated, pyrithione zinc maybe entering the cell in its chelate from, dissociating in the cytoplasm and exerting its anti-proliferative effect possibly through interaction with DNA. Alternatively, pyrithione might act by chelating metal cofactors of enzymes through its sulfhydryl group. Pyrithione has also been shown to interfere with thymidine uptake and may act as an antimetabolite for nicotinic acid or vitamin B6. Finally, pyrithione may act as a general transport inhibitor through weak-acid-induced cytosolic acidification and hence partial dissipation of the transmembrane proton motive force (PMF) on which the transport of many organic and inorganic solutes is reliant.