Simvastatin Information

What's inside Simvastatin

Recent Simvastatin Side Effects

Posted by joezen777 17 days ago
I'm only on 10mg Simvastatin and 10mg Lisinopril. I have type 1 diabetes and a minor TBI from a heat stroke. If I stop taki...

Posted by kcf370 21 days ago
My total cholesterol was 220 and LDL was 157; I started taking 40mg last week and within 2 days I just felt horrible. I felt...

Posted by ukmartian about 1 month ago
4 years ago i was given simvastatin 20mg for high cholesterol when i was diagnosed with type 2 diabetes....last year (Novembe...

Simvastatin in the News

Switching From Losartan To Candesartan Achieves Significant ... - Medical News Today (press release)
1) Evaluation of the clinical outcomes of switching patients from atorvastatin to simvastatin and losartan to candesartan in a primary care setting: 2 years ...
Fri Mar 07 04:18:05 -0500 2008

Adding niacin better than doubling simvastatin dose - Pulse
Adding extended-release niacin to simvastatin improves lipid profiles more effectively than doubling the dose of simvastatin, say US researchers. ...
Tue Mar 04 04:44:46 -0500 2008

Sensex loses 939 pts at close - Sahara Samay
Simvastatin may also interact with the other, groups. AW was funded by diet alone. Symptoms of the potential modifying factors. Based on these data indicate ...
Mon Mar 03 06:15:55 -0500 2008

Simvastatin Chemical Information

simvastatin - A lipid-lowering agent derived synthetically from a fermentation product of the fungus Aspergillus terreus. Hydrolyzed in vivo to an active metabolite, simvastatin competitively inhibits hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, the enzyme which catalyzes the conversion of HMG-CoA to mevalonate, a key step in cholesterol synthesis. This agent lowers plasma cholesterol and lipoprotein levels, and modulates immune responses by suppressing MHC II (major histocompatibility complex II) on interferon gamma-stimulated, antigen-presenting cells such as human vascular endothelial cells. (NCI04)