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SMZ-TMP DS Information

What's inside SMZ-TMP DS

SMZ-TMP DS Active Ingredients: sulfamethoxazole, trimethoprim, details.
SMZ-TMP DS Dosages & Strengths
Strength Format Route Strength Class
SMZ-TMP DS 800 mg-160 mg tablet oral 1.0 each OTC
SMZ-TMP DS 800 mg-160 mg tablet oral 1.0 each OTC

Recent SMZ-TMP DS Side Effects

Posted by amybrown 24 days ago
Headache or Migraine sufferers BEWARE! I was prescribed this medication for an upper respiratory and double ear infection. A...

Posted by gregorys3521 24 days ago
June 9th 2009 after taking smz/tmp ds 800-160 for seven days I have not sleep at night ocean sound or electrical like nois...

Posted by dwatson about 1 month ago
After taken 6 pills ,1every 12 hrs.approx: 3 days My eyes lids swoll up Bags under them,Rashes developed all over.Blisterd Re...


SMZ-TMP DS Chemical Information

sulfamethoxazole - A broad-spectrum, short-acting sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with antibacterial property. Sulfamethoxazole competes with PABA for the bacterial enzyme dihydropteroate synthase, thereby preventing the incorporation of PABA into dihydrofolic acid, the immediate precursor of folic acid. This leads to an inhibition of bacterial folic acid synthesis and de novo synthesis of purines and pyrimidines, ultimately resulting in cell growth arrest and cell death.

trimethoprim - A synthetic derivative of trimethoxybenzyl-pyrimidine with antibacterial and antiprotozoal properties. As a pyrimidine inhibitor of bacterial dihydrofolate reductase, trimethoprim binds tightly to the bacterial enzyme, blocking the production of tetrahydrofolic acid from dihydrofolic acid. The antibacterial activity of this agent is potentiated by sulfonamides. (NCI04)





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