| SMZ-TMP DS Dosages & Strengths | ||||
|---|---|---|---|---|
| Strength | Format | Route | Strength | Class |
| SMZ-TMP DS 800 mg-160 mg | tablet | oral | 1.0 each | OTC |
| SMZ-TMP DS 800 mg-160 mg | tablet | oral | 1.0 each | OTC |
Posted by cynthiaval 15 days ago
I started the antibiotic on sept 23rd at night. Everything was going good until Monday night. I started having problems sleep...
Posted by vjg12 about 1 month ago
When I took SMZ-TMP DS; The day after i could not move my legs without being in agony pain. I didn't think anything about it....
Posted by crystal2kaye about 1 month ago
I have been on this medication for 4 days now with NO problems what-so-ever. I dont know what the big fuss is about.
sulfamethoxazole - A broad-spectrum, short-acting sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with antibacterial property. Sulfamethoxazole competes with PABA for the bacterial enzyme dihydropteroate synthase, thereby preventing the incorporation of PABA into dihydrofolic acid, the immediate precursor of folic acid. This leads to an inhibition of bacterial folic acid synthesis and de novo synthesis of purines and pyrimidines, ultimately resulting in cell growth arrest and cell death.
trimethoprim - A synthetic derivative of trimethoxybenzyl-pyrimidine with antibacterial and antiprotozoal properties. As a pyrimidine inhibitor of bacterial dihydrofolate reductase, trimethoprim binds tightly to the bacterial enzyme, blocking the production of tetrahydrofolic acid from dihydrofolic acid. The antibacterial activity of this agent is potentiated by sulfonamides. (NCI04)