Symmetrel Information

What's inside Symmetrel

Symmetrel in the News

Influenza virus can be serious illness - KPCnews.com
If you do come down with the flu, your doctor may recommend use of an antiviral medicine such as Tamiflu (oseltamivir) or Symmetrel (amantadine) to help ...
Sun Feb 10 15:13:35 -0500 2008

Drug-Resistant Flu Virus on the Rise - TIME
Already, US health authorities recommend against using two other flu antivirals, amantadine and rimantadine (sold as Symmetrel and Flumadine, respectively), ...
Thu Jan 31 18:08:54 -0500 2008

Scientists zero in on how flu virus outfoxes drugs - AFP
Two anti-flu drugs -- amantadine, sold as Symmetrel, and rimantadine, sold under the brand Flumadine -- were designed to block this process, ...
Wed Jan 30 14:46:40 -0500 2008

Symmetrel Chemical Information

amantadine - A synthetic tricyclic amine with antiviral, antiparkinsonian, and antihyperalgesic activities. Amantadine appears to exert its antiviral effect against the influenza A virus by interfering with the function of the transmembrane domain of the viral M2 protein, thereby preventing the release of infectious viral nucleic acids into host cells. Furthermore, this agent prevents virus assembly during virus replication. Amantadine exerts its antiparkinsonian effects by stimulating the release of dopamine from striatal dopaminergic nerve terminals and inhibiting its pre-synaptic reuptake. This agent may also exert some anticholinergic effect through inhibition of N-methyl-D-aspartic acid (NMDA) receptor-mediated stimulation of acetylcholine, resulting in antihyperalgesia.