Trental Information

What's inside Trental

Trental in the News

American Chemical Society Health News - Medical News Today (press release)
The new study also found that Trental, reported to have beneficial effects in preventing certain diabetic complications, may work by boosting ATP release ...
Wed Jul 18 04:05:05 -0400 2007

Red Blood Cells 'Talk' To Platelets, With Implications For Diabetes - Science Daily (press release)
The new study also found that Trental, reported to have beneficial effects in preventing certain diabetic complications, may work by boosting ATP release ...
Mon Jul 16 20:21:27 -0400 2007

Red Blood Cells 'Talk' To Platelets, With Implications For Diabetes - Science Daily (press release)
The new study also found that Trental, reported to have beneficial effects in preventing certain diabetic complications, may work by boosting ATP release ...
Mon Jul 16 20:21:27 -0400 2007

Trental Chemical Information

pentoxifylline - A methylxanthine derivative with hemorrheologic and immunomodulating properties. Pentoxifylline inhibits phosphodiesterase, resulting in increased levels of cyclic adenosine monophosphate (cAMP) in erythrocytes, endothelium, and the surrounding tissues. This leads to vasodilation, improves erythrocyte flexibility, and enhances blood flow. In addition, the increased level of cAMP in platelets inhibits platelet aggregation, which may contribute to a reduction in blood viscosity. This agent also inhibits production of tumor necrosis factor-alpha and interferon-gamma, while it induces Th2-like (T-helper 2) cytokine production, thereby inhibiting Th1-mediated (T-helper 1) inflammatory and autoimmune responses.