Tramadol (Ultram, Tramal (see below)) is a centrally-acting analgesic, used for treating moderate to moderately severe pain.
Tramadol is a synthetic stripped-down piperidine-analog of the phenantherane alkaloid Codeine and, as such, is an Opioid and also a pro-drug (Codeine is metabolized to Morphine, Tramadol is converted to M-1 aka O-desmethyltramadol). Opioids are chemical compounds which act upon one or more of the human opiate receptors (the euphoria, addictive nature and respiratory depression are mainly caused by the Mu(μ) 1 and 2 receptor. The opioid agonistic effect of Tramadol and its major metabolite(s) are almost exclusively mediated by the substance's action at the μ-receptor. This characteristic distinguishes Tramadol from many other substances (including Morphine) of the opioid drug class, which generally do not possess Tramadol's degree of subtype selectivity.
| Ultram Dosages & Strengths | ||||
|---|---|---|---|---|
| Strength | Format | Route | Strength | Class |
| Ultram 50 mg | tablet | oral | 1.0 each | OTC |
Posted by shamrock about 1 year ago
I was prescribed Ultram for chronic back and neck pain because I had been on Vicodin for a long time but did not want to be on a strong narcotic long-term. Ultram is effective, but i have been on it almost a year and if I run out and don't happen to have any more, after about 12-24 hours I start sweating and I feel weak and can't sleep, plus legs twitch uncontrollably. I guess all pain meds have their problems.
Posted by questorb about 1 year ago
Drove 500 miles from home...forgot to renew my ultram. Doctor would not renew without me coming in (have taken it for over two years). After 3 days could not sleep, my arms and legs would jerk uncontrollably, I wanted to cut them off. After six days I went to emergency. They gave me a five day dosage of Ultram. After one day back on...everything was back to normal. Over the phone my doctor told me to take Motrin!!! As soon as I see him (today) and get a prescription,,,I will change doctors.
Posted by susan225 about 1 year ago
This is effective for arthritis. Works better than anything else with Meloxicam.
FBI probe leads to Coshocton man's arrest - Coshocton Tribune
The September and October controlled drug transactions involved Percocet and Ultram. Stephen Finck, 34, 841 Kenilworth Ave., entered guilty pleas to one ...
Fri Mar 07 08:04:21 +0000 2008
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Woman arrested on prescripton drug fraud - Madison Courier
She allegedly called in prescriptions for Ultram and Tramadol, which are pain relievers. Police said Mason then gave names of her family members to the ...
Fri Feb 29 15:11:06 +0000 2008
tramadol hydrochloride - A synthetic codeine analogue, Tramadol Hydrochloride has central analgesic properties with effects similar to opioids, such as morphine and codeine, acting on specific opioid receptors. The hydrochloride salt of Tramadol and used as a narcotic analgesic for severe pain, it can be addictive and weakly inhibits norepinephrine and serotonin reuptake. (NCI04)