Uniretic Information
What's inside Uniretic
Uniretic Active Ingredients: hydrochlorothiazide, moexipril hydrochloride, details.| Uniretic Dosages & Strengths | ||||
|---|---|---|---|---|
| Strength | Format | Route | Strength | Class |
| Uniretic 12.5 mg-15 mg | tablet | oral | 1.0 each | OTC |
| Uniretic 25 mg-15 mg | tablet | oral | 1.0 each | OTC |
| Uniretic 12.5 mg-7.5 mg | tablet | oral | 1.0 each | OTC |
Recent Uniretic Side Effects
Posted by adrodny over 2 years ago
swollen and aching feet ,on the top at the base of the middle toes. It was the only medication I was taking at the time, and ...
Posted by kathleen794 over 3 years ago
It is questionable as to whether the condition is related to reflux, allergies, or side effects.
I have had a hoarse thro...
Posted by nancy.samm over 4 years ago
Very itchy welpy rash over arms, legs, back and upper chest.
Uniretic in the News
First Quarter Report 2007: Schwarz Pharma with Good Start - PharmaLive.com (press release)
This is due to lower sales of high margin products (eg generic omeprazole, Univasc®/Uniretic®). Selling, general and administrative expenses rose by 2.1% to ...
Wed Apr 25 05:30:02 -0400 2007
Uniretic Chemical Information
hydrochlorothiazide - The hydrogenated derivative of chlorothiazide, a thiazide diuretic with antihypertensive and anti-urolithic effects. This agent binds to the electroneutral Na-K-Cl cotransporter (NKCC) and thereby impairs Na+, K+ and Cl- reabsorption on the luminal membrane of the early segment in the distal convoluted tubule in the kidney. This leads to an increase in urinary excretion of sodium, chloride, potassium, bicarbonate and water subsequently reducing plasma and extracellular fluid volume leading to a reduction in blood pressure. Hydrochlorothiazide also decreases urinary calcium and uric acid excretion by direct action on the distal tubule.
moexipril hydrochloride - The hydrochloride salt form of moexipril, a prodrug and non-sulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. Moexipril hydrochloride is hydrolized into its active form moexiprilat, which competitively inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the actions of the potent vasoconstrictor angiotensin II and leads to vasodilatation. It also prevents angiotensin II-induced aldosterone secretion by the adrenal cortex, thereby promoting diuresis and natriuresis. Moexipril hydrochloride also directly suppresses renin release.
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