Verdeso Information

What's inside Verdeso

Verdeso in the News

DUSA Announces Stiefel's Receipt of Pricing Approval of Levulan ... - PR-USA.net (press release)
... Olux TM (clobetasol propionate) Foam, 0.05%; Olux-E TM (clobetasol propionate) Foam, 0.05%; Soriatane ® (acitretin) capsules; Verdeso TM (desonide) Foam ...
Sun Mar 09 18:41:05 -0400 2008

DUSA Expands Global Sales With Launch of Levulan(R) Kerastick(R ... - Trading Markets
... MimyX(R); Olux(TM) (clobetasol propionate) Foam, 0.05%; Olux-E(TM) (clobetasol propionate) Foam, 0.05%; Soriatane(R) (acitretin) capsules; Verdeso(TM) ...
Mon Oct 01 03:36:23 -0400 2007

FDA Approves Extina(R) for the Treatment of Seborrheic Dermatitis - PR Newswire (press release)
... 0.05%; Olux-E(TM) (clobetasol propionate) Foam, 0.05%; Soriatane(R) (acitretin) capsules; Verdeso(TM) (desonide) Foam, 0.05%; Brevoxyl(R) Creamy Wash ...
Tue Jul 17 03:06:51 -0400 2007

Verdeso Chemical Information

desonide - A synthetic glucocorticosteroid for topical use, with anti-inflammatory activity. Desonide binds to glucocorticoid receptors in the cytoplasm, and the ligand-receptor complex is translocated as a homodimer into the nucleus, where transcription activation via glucocorticoid response elements within glucocorticoid-responsive genes occur. This agent induces transcription of genes coding for anti-inflammatory proteins, including lipocortin-1, interleukin-10, interleukin-1 receptor antagonist and neutral endopeptidase. Increased synthesis of lipocortin-1 has an inhibitory effect on phospholipase A2, which in turn inhibits the release arachidonic acid, thereby controlling the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes.