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Vytorin Information

What's inside Vytorin

Vytorin Active Ingredients: simvastatin, ezetimibe, details.
Vytorin Dosages & Strengths
Strength Format Route Strength Class
Vytorin 10 mg-40 mg tablet oral 1.0 each OTC
Vytorin 10 mg-10 mg tablet oral 1.0 each OTC
Vytorin 10 mg-20 mg tablet oral 1.0 each OTC
Vytorin 10 mg-80 mg tablet oral 1.0 each OTC

Recent Vytorin Side Effects

Posted by swedish 29 days ago
To all of you here I would suggest that you also read messages for the others statins such as for instance Lipitor, Zocor and...

Posted by gatormom 29 days ago
Was on Vytorin for 2 years & experienced no noticeable side effects during that time. It lowered my cholesterol to 179. Had a...

Posted by pam2p4 29 days ago
headache,memory loss,muscle pain,fatigue,insomnia.


Vytorin in the News

Concerns over Vytorin, Avandia prompt investigation of FDA review - WOI
The Government Accountability Office wants to know if GlaxoSmithKline's diabetes pill Avandia and the cholesterol drug Vytorin -- made by the New ...
Tue Mar 04 23:02:35 -0500 2008

FDA faces scrutiny for review process on Avandia, Vytorin - San Francisco Chronicle
Inc. and Schering-Plough's cholesterol drug Vytorin. The Iowa Republican requested the investigation after recent studies suggested the drugs may not lower ...
Wed Mar 05 08:57:53 -0500 2008

Allure fades for shares of drug makers their shine - International Herald Tribune
The drop came after a study found that their joint cholesterol treatment, Vytorin, formed by blending two other drugs, was not significantly more effective ...
Sat Mar 01 17:14:15 -0500 2008


Vytorin Chemical Information

simvastatin - A lipid-lowering agent derived synthetically from a fermentation product of the fungus Aspergillus terreus. Hydrolyzed in vivo to an active metabolite, simvastatin competitively inhibits hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, the enzyme which catalyzes the conversion of HMG-CoA to mevalonate, a key step in cholesterol synthesis. This agent lowers plasma cholesterol and lipoprotein levels, and modulates immune responses by suppressing MHC II (major histocompatibility complex II) on interferon gamma-stimulated, antigen-presenting cells such as human vascular endothelial cells. (NCI04)

ezetimibe - An azetidinone derivative and a cholesterol absorption inhibitor with lipid-lowering activity. Ezetimibe appears to interact physically with cholesterol transporters at the brush border of the small intestine and inhibits the intestinal absorption of cholesterol and related phytosterols. As a result, ezetimibe causes a decrease in the level of blood cholesterol or an increase in the clearance of cholesterol from the bloodstream. Overall, the following effects observed are a reduction of hepatic cholesterol stores and a reduction of total cholesterol, LDL cholesterol, and other triglycerides in the blood.



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