Vytorin Information
What's inside Vytorin
Vytorin Active Ingredients: simvastatin, ezetimibe, details.| Vytorin Dosages & Strengths | ||||
|---|---|---|---|---|
| Strength | Format | Route | Strength | Class |
| Vytorin 10 mg-40 mg | tablet | oral | 1.0 each | OTC |
| Vytorin 10 mg-10 mg | tablet | oral | 1.0 each | OTC |
| Vytorin 10 mg-20 mg | tablet | oral | 1.0 each | OTC |
| Vytorin 10 mg-80 mg | tablet | oral | 1.0 each | OTC |
Recent Vytorin Side Effects
Posted by annvickm about 1 month ago
I have been on vytorin for about a year and a half now and I do experience some side effects. I get up at night at least 2 t...
Posted by fryguy67 3 months ago
Wow, wish I had read this a long time ago. I have been on Vytorin 10/10 for 2+ years. Have many of the same complications a...
Posted by wigstudio 4 months ago
Has anyone experienced muscle loss of the heart since they are on vytorin? In 15 months on Vytorin my heart ejection fractur...
Vytorin in the News
Concerns over Vytorin, Avandia prompt investigation of FDA review - WOI
The Government Accountability Office wants to know if GlaxoSmithKline's diabetes pill Avandia and the cholesterol drug Vytorin -- made by the New ...
Tue Mar 04 23:02:35 -0500 2008
FDA faces scrutiny for review process on Avandia, Vytorin - San Francisco Chronicle
Inc. and Schering-Plough's cholesterol drug Vytorin. The Iowa Republican requested the investigation after recent studies suggested the drugs may not lower ...
Wed Mar 05 08:57:53 -0500 2008
Allure fades for shares of drug makers their shine - International Herald Tribune
The drop came after a study found that their joint cholesterol treatment, Vytorin, formed by blending two other drugs, was not significantly more effective ...
Sat Mar 01 17:14:15 -0500 2008
Vytorin Chemical Information
simvastatin - A lipid-lowering agent derived synthetically from a fermentation product of the fungus Aspergillus terreus. Hydrolyzed in vivo to an active metabolite, simvastatin competitively inhibits hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, the enzyme which catalyzes the conversion of HMG-CoA to mevalonate, a key step in cholesterol synthesis. This agent lowers plasma cholesterol and lipoprotein levels, and modulates immune responses by suppressing MHC II (major histocompatibility complex II) on interferon gamma-stimulated, antigen-presenting cells such as human vascular endothelial cells. (NCI04)
ezetimibe - An azetidinone derivative and a cholesterol absorption inhibitor with lipid-lowering activity. Ezetimibe appears to interact physically with cholesterol transporters at the brush border of the small intestine and inhibits the intestinal absorption of cholesterol and related phytosterols. As a result, ezetimibe causes a decrease in the level of blood cholesterol or an increase in the clearance of cholesterol from the bloodstream. Overall, the following effects observed are a reduction of hepatic cholesterol stores and a reduction of total cholesterol, LDL cholesterol, and other triglycerides in the blood.
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