Abdominal muscles symptoms and conditions

I had ankle surgery in March 2009. After several weeks of pain and inflammation, my doctor prescribed a Prednisone dose-pak to "settle everything down." Yesterday, day 1, I took 2 pills before breakfast, 1 after lunch, and 1 after supper. About 4 - 4 1/2 hours after taking my supper dose, I developed SEVERE abdominal pain (akin to labor pains) and diarrhea that lasted for several hours. The pain abated during the night and today I have had very sore abdominal muscles and a little bit of an upset stomach. I never took the bedtime dose

I don't care how much pain I have had in my ankle...nothing compares to the pain I experienced last night. I will never take this medicine again. According to all the information I have read about side effects, nothing indicated I would experience pain like this.

I am hopeful that now the stomach/abdominal pain "settles down."

I have type 2 diabetes for a few years and am 59 yrs old-and do not have fibromyalgia or kidney,liver problems or depression or a history of any painful muscles ever. I work up to 90 hrs a week as a doctor for the past 12 years and am a DIY renovator of my home in mt free time. I exercise regularly and am fairly fit, I do have a congenital mitochondrial myopathy characterized by non painful arm and leg muscle weakness- but have not been symptomatic significantly for 20 years. I take vitamins and one aspirin a day and have no medication allergies. weeks ago I started Januvia- my only diabetes medication. I worked well to normalize my mild to moserate elevation of BS.Over the past 2 weeks or so, I have had an increased somnolence without feeling rested upon awakening. I felt like I had been beaten with telephone poles and hammers, More distressing is the insidious onset of neuromuscular pains episodic sharp ones, more persistent aching and burning and tingling tingling, with a dense heaviness in legs more than arms worse with exertion and relieved by rest. 3 days ago it was to the point where I had to stop walking after 8 steps and could not climb a ladder beyond one step . I should not curl 2 lb weights even twice, Typing on a keyboard fatigued my arms after 5 minutes. I stopped Januvia three days ago, slept 30 hours,, felt better yesterday,restarted januvia last pm, Today, after 12 hours of sleep I feel exhausted like I did hard manual labor for a few days without ant sleep. The telephone pole beaten feeling returned, My weakness and pain are back with a vengeance and I cannot walk very well and have to stop typing this every 2 or 3 minutes to rest my arms, and have weakness also in my back muscles with curious sparing of abdominal muscles. Heat and massage do not help and are uncomfortable. I feel tired like I do when my myopathy acts up and my Krebs cycle is disrupted and thus my mitochondria do not make ATP to power my muscles- with the additional new symptom of significant pain. Aside from a mild tachycardia of about 100 at rest, my vital signs are normal, my cpk, Mg, thyroid function tests, comprehensive metabolic panel and sed rate are all normal . Heavy metal screen is negative. I will stop Januvia and probably never take it again, If my glucose goes back up I will go back to metformin which I took a few months about a year ago,
I suspect in my case that Januvia disrupted my mitochondrial function as well as being additionally toxic to my muscles and nerves by some additional pathogenesis, I question whether those individuals who have weakness, somnolence and neuromuscular symptoms might have some underlying mitochondrial dysfunction - a very under diagnosed condition - patients being told that their symptoms are of psychiatric origin.

To all my other sufferers of this hell, I too have been thru this agony. This started on March 12,following an pnuemonia attack. My dr. prescribed leavquin because he felt that it would attack the virus better.I took the 750mg dosage for 10 days & actually started felling normal again. I returned to work without any side affects,doing everything that I always had. But then,out of the blue and 13 days later, I started feeling bad. Me being a truck driver,I experienced the leg cramps,joint popping,light headedness,shortness of breath & fatigue. I thought I went back to work too early after the pnuemonia .The next day I had body aches all over but I had a family function to attend so I went with the pain. 3 hours into the evening I got up to go to the restroom & this is were my hell has started. Lack of breath,dizziness,unable to walk & 20min. later,severe chills. We left the party & arrived home with the chills and 102 temperature. I thought I would sweat this out but I was wrong! I wound up going to ER where my body was off the charts,elavated vitals,severe chills & muscle aches. ER setup an IV and a monitor. BP was 177/117,pulse 107,wcbc was 19,oxygen/blood ratio was92. I recieved 2 pushups of dilonted and that supressed the chills & fever. 9 hours later I was sent home with a 104 temp,messed up vitals and was told to follow up with my Dr. Saw him 2 days later,told him that i was weak,nauseous & had a bad sore throat. He gave me tagamet,have a echograph for my heart,blood work& sent me home. 5 hours passed,then he says he wanted to admit me to hosp.for "observation".
The next morning I awoke in a sweat, my throat had completly closed and my sinuses had open causing me to gag on mucus. I was so bad that i could not swallow water,even small sips and my abdominal muscles were sore from from coughing. Needless to say,in brief,I have been tested for lupus, viral infection for sinus,lung,stomach,uti & prostate(complete with biopsy testing) and full xrays of legs & spine. My veins are collasped from all the blood draws(9)-"37 vials & counting", guess what...SO FAR EVERYTHING IS NEGATIVE!!! So it has been 7 weeks,instead of doing normal activities like walking the dog,yard work,sports,etc, I am walking with a cane,have shortness of breath,extreme cramping of my calf muscles,popping joints & lots of fatigue. Next set of tests are neuromuscular & to check for the "parvovirus"(I'm not a DOG!) but now the doc seems it is related to my dog of 12 years that stays at home & never leaves the yard. The dr & his collegues still wont admit that this is the "horrific side effects attributed to Levaquin", but we all know better,may we all strive to get well!

Hello all,

I myself live in Canada, but a brother of mine, who still lives in Germany, seems to be suffering from the typical statin-drug adverse effects. He is off the drugs now, but the symptoms persist. What can he do to rehab himself.

Here the symptoms: impaired muscular coordination impaired sense of balance... can walk only with a stick. Impairment of finer motor skills - he has difficulty writing and he experiences difficulties swallowing. Slurred speech. Listening to him you'd think he is more than a little drunk. He feels dizzy, disoriented; pain at the back of the neck; pain in abdominal muscles
and in legs. He has trouble raising his arms to reach for something up a little higher than his head and experiences intense pain if he tries to hold an arm up in a horzontal position for more than say a minute.

He was on two German statins, one called "Zokor" and the other "Baycol" for some five years. He went to see half a dozen doctors and came away with half a dozen different diagnoses till finally one took the time to find out what drugs he was on and suggested he go without the statins for a while.

Has been off the drugs for more than a year but the side effects, though somewhat improved, persist. What can he do to rehab himself faster?

Thanks for any suggestions.

waterbuf, alias Bud ***