Abnormal blood symptoms and conditions

I am a 48 year old woman, 5'1" (now 145 pounds). I had Mirena inserted almost exactly 5 years ago, and am scheduled to have it removed in 2 weeks. I gained 25 pounds over the course of the last three years; prior to that, my maximum weight for my whole (non pregnant) life was 123 (I was at 120 when Mirena was inserted, four years after the birth of my second child). I have always been very healthy, never abnormal blood tests except during my two pregnancies was tested as pre-gestational diabetic and had to watch my carbs.

I never put it together with Mirena until just recently, when I started doing research on hypothyroidism after a friend told me that my symptoms could be due to that problem. Depression, hair loss, acne on my back, and the terrible weight gain. I went to see my G.P. who referred me for blood work. I hoped to see evidence of low thyroid function (actual TSH value, 3.12 -- I was told this is normal on a range of .4 to 4.5). I also discovered that I now have high cholesterol (269 triglycerides, 251 total cholesterol, 46 HDL, and 151 LDL). My fasting (14 hours) glucose # is 99 (I was told this is normal on a range of 65-99 mg/dL), and my vitamin D, 25-OH is 21 (also was told this is still normal but low on a range of 20-100 ng/mL). I tried to give blood six months ago, and was turned down because of anemia, so I've been eating a lot of spinach, greens, and more red meat than I normally would, so I was interested to see if I am still anemic -- the red blood cell count is 3.8 (told it was normal on a range of 3.8-5.1 mill/uL). I mention these specific results because although I was told they were normal (except for cholesterol), when I physically went to the doctor's office and requested a copy of the results and did some research online I see that my thyroid IS actually low-functioning -- according to guidelines revised six years ago, anything over 3.0 is considered hypothyroid and should be treated. Plus, isn't a fasting glucose of 99 pretty high? Yet my doctor's only suggestion: diet and exercise. Good grief, I've been on a diet since I had my first child, 13 years ago. True, I don't exercise regularly (I'm a teacher and mom of 2; I never seem to have the me time.) I guess I have an excuse to get a gym membership now.

Also, for the last year I've had increasing pain in my shoulder (I couldn't lay on my side, for example, and lately I can't reach behind me or over my head). An x-ray turned up mild bone degeneration, but not enough to cause the pain I've been having. I was referred to an orthopedist, who today diagnosed a shoulder rotator cuff injury (I've had no injury; he says it is a common degenerative complaint in the over-40 crowd). He gave me a cortisone injection and I'll be on PT for a while to see if the pain goes away. If not, I'll have to have an MRI and surgery to correct the tear.

I'm posting all of this in case it might be useful to someone out there who might be going through the same thing. I had a thyroid test done about six years ago at my OB/GYN, and it was normal then (though I don't have the number; I'll get it in 2 weeks at the OB/GYN). It will be interesting to learn whether my thyroid level has gone up since Mirena. Also, although my research suggests that the effects of these synthetic hormones do not wear off for some time, possibly even years, I will finally feel like there may be hope if my symptoms improve over the next few months when Mirena is gone. If so, I will share it with you.

If you are reading this, perhaps you have a similar story. I wish I had been more aggressive about checking out the possible causes of my many symptoms, but I let them go for years because, I guess, I just figured I'm a healthy woman who is no longer young. (Oh, one more thing: for the first year or even two years that I had Mirena, I had incredibly heavy periods. The blood flow was similar to that during the day or two after the vaginal births of my daughters. Don't know if that's significant, but it took a couple of years for my periods to get fairly normal on Mirena.)

I can't believe I didn't find this sooner! I was on the Nuvaring for about 4 years and just last month traded it in for the Mirena.

At first, I was thrilled to find the Ring as I have a very hard time taking pills because I've always had a sensitive stomach. The patch was messy and sticky so I was excited to find the ring. For the first couple of years, the only problem I had was keeping it in place (it would continuously fall out) so I just got used to having to push it back into place every time I used the restroom. Every. Single. Time. But it was worth it because it made my periods much, much lighter and more manageable (i usually am down for the count for a few days). I also did the ring continuously without taking a week off because I still had some pretty terrible periods.

About two years ago, I started gaining weight uncontrollably, became very depressed, lethargic and achey. One day I came down with a terrible case of bronchitis and was put on a heavy duty round of antibiotics and steroids. After, I started having terrible heartburn and IBS symptoms which lead me to a gastroenterologist. Every test imaginable was performed, but nothing was found. I was told I had a nervous stomach. Unsatisfied, I got some bloodwork done and had abnormal blood glucose levels. My diabetic husband gave me a glucometer and I realized my blood sugars were totally out of range. I ended up at an Endocrinologist and all tests came back normal. I was also referred to a Rheumatologist for my achy body and joints. I found a list of symptoms of hypothyroidism and was convinced this is what I have, so I was put on a very low dose of Synthroid. At the same time, I was diagnosed with Fibromyalgia and put on a whole mess of anti-inflammatories and pain killers.

Unsatisfied with my diagnosis of Fibromyalgia and totally unwilling to admit this is something I have to live with for the rest of my life, I began working with a nutritionist who has helped me get off all the medications (except Synthroid). But still, I hadn't slept through the night in years (getting up 3-4 times a night to use the bathroom), I was terribly achy, irritable, nauseous, constipated and still gaining weight.

Recently, my insurance changed and I decided to get the Mirena. Within a few weeks, most symptoms have drastically improved, my family notices a major change. I actually slept through the night last week, only 3 weeks after using the Ring for the last time. I haven't lost any weight yet, but the fact that I even CAN exercise is monumental. More than anything, I'm thrilled at the prospect that everything was caused by the Ring, the one constant no matter what I tried, and maybe I won't have to live with Fibromyalgia for the rest of my life.

I can't say with total certainty that the NuvaRing caused all my problems, but it is absolutely astounding that all of us are experiencing the same terrible symptoms and none of our doctors have bothered to think that it could be the Ring. I'm angry about this. Why don't they know about these side effects??

Yes these side effects are listed in the package, but they're the same side effects from pretty much every medication... and I don't know about all of you but this thing came damn near close to ruining my life. I couldn't work, sleep, eat, exercise, clean my house, etc. etc. It's no heart attack or stroke, but definitely life altering.

I think health care providers need to be alerted to these symptoms and the possibility that the Nuvaring could be causing it all. It would have saved me thousands of dollars in medical bills and despair. Patients should be warned that the side effects are very real and can be debilitating. I'm almost sorry I found this so late (after I already got rid of it!) but I'm glad I found it nonetheless.

Good luck to all of you!

I have been using the NR for about 2 years now. I absolutely loved it and haven't had any issues with it. No serious side effects. BUT I saw the ad on TV about the lawsuit and it made me put two and two together. And also to research it which has explained some depression and sexual side effects that I have realize I have been having. Most serious is I have been having unexplained heart issues as of the past 3 months and my doctor cannot seem to find a reason. It feels almost as though there is something blocking the blood flow to my heart about 2-3 hours out of the day at random times during diff activities to include just sitting at my desk at work.. It is very concerning and my doctor is even less concerned. I know my body and I know when something is wrong, and something is wrong with my heart/arteries/blood flow. I am 27 yrs old, I do not smoke and i am in good health. No reason for my heart to feel the way it feels and it is SCARY. I finally decided to research the NR to see IF it has anything to do with it and I was shocked to find some of my symptoms associated with the lawsuit being filed. I have put in an inquiry to see what can be done and hopefully get some answers and get my health back to normal.

oh and here is the birth control pill side effect list...

Common side effects of oral contraceptives include loss of sex drive (libido), headaches, acne, weight gain, vaginal infections, and depression. Current research indicates that oral contraceptives increase your risk of acquiring HIV if your partner is infected. Oral contraceptives also have some uncommon but serious health risks associated with their use, especially among smokers; these include abnormal blood clotting and heart attacks, breast cancer, and gallbladder disease.

I have been on Lisinopril now for 4 months. I developed a terrible dry cough, I suffered a heat stroke after only being outside for about 45 minutes, I have episodes of what I call "Brain Freezes", when my brain will not think and I cannot talk. All these things happened while being on Lisinopril.
Only yesterday did I find out the terrible side effects associated with this drug. I have had abnormal Blood tests. In fact they are fearing that I have Lymphocytic Leukemeia.

This drug causes increase in WBC, dry cough, extreme sensitivity to heat and to sun, mental changes.
This is not a fit drug for man nor beast.
My face and eyes stay extremely puffy all the time , which is another side effect.
I refuse to take this drug any longer and will be seeing my MD. on wednesday. If he should refuse to beleive my symptoms are related to this partioculr medication, then I suppose I will find another MD.
After all our MD's. work for us. We are the boss and anyone whose Md. refuses to accept your symptoms as a side effect of this drug is not a good Md.
Find another Doctor and tkae control of your life. You know how you feel, and you know if something isn't right.

I am just questioning abnormal blood work with Lisinopril??
The following are low: Hemoglobin, Hematocrit, RBC, RDW, Neutrophil

The following is high: Lymphocytes

WBC and all else is Normal

Unfortunately I did not have labs prior to starting Lisinopril.