Ace inhibitors symptoms and conditions

I have been taking Lisinopril for years. Also I've taken numerous tests to find out why I'm so fatigued, sleep all day and more tired afer sleeping even,severe knee pain at night when laying down only... I had also put on a huge amount of weight in a month or two when I started taking it now that I come to think of it. Oh my gosh. As I continued reading everyone's posts I wanted to cry. Has this been my problem after all these years? I sleep my life away for the last few years and I'm only 40. Before I started taking it, I worked out extreme 36 hours a week and worked 50 to 60 hours a week. Now my day is trying to get up to make it to work on time for 8 or 9 hours! I've already sent an email to my endocrinologist to request a different prescription and I am not using Lisinopril anymore!! Are there any class action suits for this? This has really taken a lot from me. I only hope this is my answer, which it sounds like it is! Thank you so much for sharing your stories. I will return after time to reveal my results!

I have been taking 20mg Lisinopril for six days for 140/100 BP reduction. Muscle cramps, muscle pain, dizziness, ringing in the ears (which I already had, but this medication has made it MUCH worse),some heart palpitations...generally scary and, on balance, I am going to find some other solution. Frankly, this is like taking a slow acting poison.

So. I have read a lot here about side effects. What have you guys switched to (i.e. what BPM are you taking now)?

Who has switched to something else and been pleased with the results?

Need specifics please on an alternative.

I was taking 20 MG of Lisinopril for approximately 1 month, getting a bp reading of about 155/95, so my doctor increased the dosage to 40 MG. About 2 weeks after that, my BP is up a lot, to about 190-200/95-110. Anyone have a similar reaction?

I recently back in April of this year received Cyberknife radiation for Adenocarcinoma with metastasis to my brain. After surgery to remove my brain tumor in March of 2009. I went though whole brain radiation and the Cyberknife to my lung. The doctor was very adamant that as the lung heals from radiation you will develop what they call wet lung or neumonesis sp? This will have to be treated separately, or severe coughing would continue. My primary care doctor in the mean time put me on Lisinopril 20 mg for hypertension. I have not gotten a good nights sleep in 2.5 months since, then came the pneumonosis. This cough persist to this day waking me from what little sleep I do get, and amazingly am now suffering from joint pain especial in my hips. It's to the point I can't even cross my legs anymore it hurts. When discussing this with my primary she says its in my head as of today and reading this site and side effects I am taking myself off of Lisinopril and will seek a second opinion, even a third if need be thank you all so much for posting your side effects from this drug.

Ayurvedic Herbal Treatment for Hypertension

Hello. I have been dealing with my hypertension now for approximately 1-1/2 years now and those of you that have read my findings through my previous posts know that I'm always looking for natural supplements to stay off of the lisinopril. I stumbled onto a new herb for bp. You absolutely have to try this. I went to see my doctor yesterday and I was having a really stressed out day dealing with a family crisis and my bp was 150/100. I left with a prescription, but I received my order of this stuff in the afternoon and I took the recommended two tablets twice a day and woke up this morning with my bp 108/69. This product gets shipped from India and takes approximately two weeks to arrive by registered air mail, but very much worth the wait. I have the link to order it and to read more about the herbal treatment. If you are interested, feel free to e-mail me and I will send it to you. Take care and good luck.

I received yet another email from someone who has had a recent MRI due to memory difficulties and the MRI indicated brain shrinkage. This drug is breaking the blood brain barrier, causes depression, and is shrinking the brain. I know of 3 people who began Lisinopril and over a period of less than 2 years, have had MRI and their brains indicate shrinkage. We are wondering why Alzheimers is becoming an epidemic. More people are being prescribed Blood Pressure medicines at earlier ages, particularly Ace Inhibitors because they are cheap and these drugs are pentrating the blood brain barrier and causing a drug induced brain damage that mimicks Alzheimer symptoms. It begins to appear as depression, so, they treat the depression with anti-depressants. They improve for a period of time and then the symptoms of memory loss, difficulty retaining, concentration issues, mental sluggishness begin to present again. The Doctors are in denial, not us who are posting these symptoms. The obvious is oblivious. You cannot take a healthy individual who never took anything more than an aspirin and within 17 month of taking this medication have depression, memory issues and brain shrinkage. I hope if there are any Doctors that read this site, they pay attention to their patients and watch those people on Ace Inhibitors who then follow a pattern of memory problems and depression. It's much more than depression. I bet if all those people who experience memory difficulties got and MRI, there brains would show shrinkage.

I have been on Lisinopril for over 30 days. I started getting severe pelvic pain and a routine UA indicated I had an infection as well as blood and protein present. Dr. was worried about bladder cancer. Took sulfur based drugs for the infection and subsequent UA was clear but severe pain continued. Scheduled PAP and Dr. ordered ultrasound. He indicated that uterus was pushed over slightly to one side and indicated it could be fibro cysts. Ultrasound was normal. Dr. ordered CT scan, normal. Dr. wants to send me to gastroenterologist. It takes three 7.5 mg. Vicoprophen for pain to abate for 4 hours. I sat up all night researching and came up with isolated viseral angioedema a very rare and seldom known side affect of ACE inhibitors (Lisinopril). It affects the small bowel. Would assume that small bowel was so swollen that it was pressing on all other abdominal organs, especially bladder, causing pain. Had diarrhea at first then constipation. When looking up isolated viseral angioedema it says that gastroenterologist usually do lap surgeries looking for cause of pain before they figure out that it is the Lisinopril. Immediately quit taking and 3 days later almost pain free. If you have abdominal pain and are taking Lisinopril, cease before undergoing any further testing. It cost me $2,000 to figure it out on my own.

For just over two years I suffered with chronic sinus infections and I could not understand what the cause of it could be. My doctors (two sinus specialists and also GP) did not even know about this side effect of Lisinopril. I was on antibiotics five times last year. The sinus specialists told me I must go for sinus surgery. I tried to remember when my sinus problems started and tried to link it to something else. Then I realized that I started taking Lisinopril in September 2006. Shortly after this I had my first severe sinus infection and I almost had pneumonia from it. Shortly after I recovered (after taking a strong course of antibiotics) it was not three weeks then I had it again. I had sinus problems the whole of 2007 and 2008. I decided to do some research on the internet to see if the infections are related to Lisinopril. I was shocked to discover that so many people reported the same side effects. I requested my GP to change my BP medication to a different group (Non-ACE Inhibitor). I cannot believe the difference. No more sinus infections! Also, I had flu once so far and I managed to recover from it without the use of antibiotics. This is a real breakthrough for me. I am just glad that I found this forum.
JM, South Africa

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I've been noticing that you as well as bobby are continuously replying to many of the posting. I stopped taking lipitor in December after having chest pains for 10 months which included being hospitalized for 2 days of testing. I'm still having the chest pain although I believe it's getting better. There was a week in the beginning of this month that I had no pain at all but now it's back. My question to you and bobby is you keep saying you still have some side affects for months but fail to list them. What are they and with your experience, why does Lipitor cause chest pain? What have you found out in your research? Is this drug causing damage to the interior lining of the arteries? Is this why many people are getting the pains from?

Is anyone experiencing confusion, trouble thinking, trouble concentrating, decreased cognitive function, mental sluggishness, trouble solving problems or situations which require logical thinking and sequencing, and memory loss? Would love to hear from anyone experiencing any these symptoms and if so, how long were you on the drug.
Thanks!

Well, I beg to differ with "huh1051" regarding the snake venom. This is straight from "Wikipedia"... History/brand names
Lisinopril was developed by Merck & Co. and is marketed worldwide as Prinivil or Tensopril and by AstraZeneca as Zestril. In India it is marketed by Micro Labs as Hipril. In the United States, a generic version is available. Like other ACE inhibitors, it is derived from the venom of the jararaca, a Brazilian pit viper (Bothrops jararaca). So, "what" do you believe!!!???? This drug breaks the blood brain barrier which is probably why so many people get depression. However, I "think" this drug is causing more than just depression. It's shrinking the brain and affecting memory.
bellabear

I just started taking Lisinopril 2 weeks ago for my high blood pressure, I'm coughing all the time with mucus, my left rib cage feels like somebody is continuously stabbing me in the same spot and then afterwards I would get a weird tingling sensation, I've lost my voice, I'm hungry all the time, I urinate way more than usual, I get irritated easily and start yelling at people when they haven't done anything, I'm exhausted from doing nothing. This medicine is terrible, I'm going to my doctor tomorrow and tell her that I'm going to stop taking it, I don't care, it's just not worth all the side effects.

I am a 56 yr old female, placed on Lisinopril in lieu of Atelenol, which I have been taking along with HCTZ for a least 5 years. BP was 148/83, Dr. thinks still too high so Lisinopril it is. I was on it for a week and I, too, developed some really annoying side effects. Dry, almost spastic cough, especially at night when I attempt to sleep. Have been on the sofa for over two weeks to avoid disturbing my other half's sleep with my constant coughing. The Lisinopril makes me tired anyway but with the lack of sleep, I am exhausted. I am also an Multiple Sclerosis patient and fatigue is a big factor of the disease so lack of sleep is not good. I had the perpetual headache everyday, not debilitating but enough to ruin your day. Also felt extremely dizzy, to the point of feeling like I could pass out when I raised my head. The newest symptom, is a sore tongue. Feels like I have many cuts on the front of my tongue which foods and drink irritate but there is nothing there. Dr. has taken me off saying that I am experiencing an allergy to Ace Inhibitors and switched me over to another med called Benecare. Have not taken one yet and will do so along with the Atelenol so don't know how it will be but just wanted to share the allergy concept about Ace Inhibitors.
Take Care All

We all know that Lisinopril sucks and I was wondering what other type of Ace Inhibitors have worked or are working for you? Thanks people this has been very helpful..

I am so thankful for this site. I thought maybe it was just me. For one, I am allergic to Sulfa. My doctor knows this, as does my pharmacy. Still, they give me Lisinopril with Hydrochlorothiazide which you should NOT take if you have a sulfa allergy. From day one, I started with anxiety, agitation, nausea and what felt like a racing heart - though my pulse was normal. Day three I called the doctor and they said this was normal as my body "adjusted" to the medication. It has been over two weeks and the same thing keeps happening. I tried taking the meds at night to hopefully sleep through the side effects but no - it just kept me awake. I put another call in today and have yet to receive a return call from my doctor. I hope the doctor calls me and NOT the front desk girl because I have a lot of questions and concerns. Other symptoms I have been experiencing since I started Lisinopril are sever muscle cramping last for over 24 hours, dizziness, heavy chest/racing heart beat, restlessness and less frequent urination. For a 37 yo female who has to "potty" constantly, even throughout the night, going once in an 8+ hour period is not normal! The worst side effect though is definitely the anger and agitation. I feel like I am going to burst out of my skin or die banging my head against the wall. Last night I tossed and turned for 2 hours in agitation. I thought I would surely have a heart attack from the stress. Oh yeah my BP has NOT dropped at all (tho it fluctuates on or off the meds) on the 20 mg dose. Go figure.

This is a follow-up to my posting on October 10th regarding my 57 year old husband who began taking Lisinopril in March of 2007. He was NEVER on any other medication prior to taking this drug. He suffered Depression, loss of memory, lack of concentration, can't focus and struggled with small task. We have recently had an MRI done and his brain has shrunk. Deadfred1 replied to my posting and he is a 36 year old male who has been on Lisinopril for 5 years. He has the same side effects as my husband. He had a recent MRI and his brain has shrunk!!! We visited a Neurologist with his MRI results for a second opinion and he is ordering more tests because "it appears to be indictive of Alzeheimers" with the area of the brain that has shrunk. How can this be??? This was a healthy, 57 year old NEVER on a drug in his life and within months of taking this, he is in Depression and having memory issues. Isn't anyone connecting any symptoms here??? Any Doctors out there with an "open mind"? This medication is was developed from the venom of a poisonous Brazilian snake!!! Hello...it's more like a slow death with Arsenic!!! My mother-in-law has been on this drug for years and years and years. She now sits with dementia in an Alzeheimers unit. Is anybody out there listening? Alzeheimers is becoming an epidemic in this country. Have we ever thought the medications we are taking is creating this devastating disease? Millions of people take Ace Inhibitors, millions of people have Alzeheimers. They are getting younger and younger according to the Neurologist. Why, because younger and younger people are being put on Blood pressure medications from poisonous snakes. Are there any open minded Dr.s out there that can "step outside the box"...don't just "think outside the box"...."step out for goodness sake" and start paying closer attention to the symptoms people are having. I am convinced there is a definite connection to my husbands side effects and this drug. Get off people. Get off.

I am a male 55. Started taking Altace 15 years ago. BP kept creeping up. I work outside for a living. Sometimes work is very hard, climbing mountains, carrying land surveying equipment ect. Dr started me on lisinopril 40 mg, dropped altace which I had been taking with HCT 25mg. Started getting numbness in left hand and charley horse in elbow after playing mandolin for 10 minutes. I thought this strange. Now I have muscle cramps in legs and I am wiped out when I get home. (thought must be getting old) Then other joints, shoulders, and knees stared hurting and lower back. Started thinking what has happen to me?! I am completely falling apart! That's how I found this web site. Now I wonder, snake venom sounds about right. I had started thinking I had been poisoned. Guess I'll make a DR appointment or move to an "old folks home". At least I won't have a stroke.......right?

I am a 48-year-old male that is still pretty active playing competitive soccer several times per week. I am in good health except that my BP was considered a little high back four years ago and was originally put on a diuretic which made me cramp up easily on the soccer field. I asked my doctor for something different and was changed over to Atenolol. I have been living with the Atenolol side effects for that time and finally had enough. I had recently moved and changed doctors. Now was a good time to complain about the restless nights that I attribute to Atenolol (insomnia is one side effect). My new doctor knowing that I am an athlete suggested Lisinopril.
Again, my research is after the fact and was really spurred by a trip back home and a chat with my brother who is 49 and was just recently put on Liprinopril too. He described some bazaar conditions that he believed were Lisinopril side effects. When researched, he was right. He experienced the blackness or tunnel vision and the feeling of passing out while at work. He felt that he couldn’t drive as the effects where hampering his ability to do so. He stopped taking the drug and started a regiment of fish oil with his other daily supplements. This was two months ago and he is doing great. He too is still an athlete and runs in Masters Track & Field.
For me, it was a little different. I started Lisinopril on a Friday as my Atenolol had just run out on Thursday. I asked the Pharmacist if there was an issue with starting Lisinopril after stopping Atenolol only one day apart. She said there were no issues. 5 days later, Wednesday, while at work I developed an incredible lower back pain on the left side. I began to have nausea and heavily salivate as if I was going to throw up. I ran to the bathroom where I sat on the toilet for a half hour rubbing my back & hip believing it was some intestinal issue or gas. To no avail… When I felt stabile enough, I left work only to sit in my car wondering if was going to be able to drive and if I could should I drive home or to the hospital. Well, I drove home and went to bed for a couple of hours before I felt well enough to function normally. It’s been two weeks and the dull lower back pain that feels similar to a back strain persists. I’ll be heading back to the doctor with this information and will start the fish oil with my daily supplementation program.
Thanks to this website because I was able to find at least five examples out of about the first twenty postings that matched my suspected side effects.

I took Lisinopril for 3 months. Symptoms gradually got worse: eyes watered, nose dripped, ears itched, puffiness under eyes, hair loss, tired all the time, body was very tense, night sweats, couldn't sleep well, and started having sharp pains like pin pricks. The doctor said to stop Lisinopril and switch to Cozaar (for Losartan). I didn't want to start another medication until I got this out of my system, so I stopped Lisinopril 4 days ago. My symptoms started to subside in about 3 days, but then I started to get horrible cramps behind my thighs. For 2 days now the pain keeps me awake at night...I can't get comfortable. At 11:00 p.m. tonight I had to take 1 Lisinopril to "wean" off this horrible drug. I don't have hypertension, but was recently diagnosed with type 2 diabetes--so the medicine is supposed to "protect" my kidneys. Does anyone know whether Cozaar is any better? I hate taking meds!

Started Lisinopril on April 7, by June 28, could not get a deep breath when I needed it, like when you yawn....went to a pulmonary doc and he took me off the lisinopril that my primary dr. had given me because he said it had ace inhibitors in it and was interfering with an enzyme in my throat. He said would take about six weeks for this to get out of my system, I only have 6 days left, does anyone know how long it takes to get out of your system.

j.

Horrific muscle cramps, twitches or fluttering in my heart/chest. Aches, pains, depression, feeling old, having lots of hair come out each day, thinking it looks like more than it should be, swollen stomach/bladder/uterus, urge to pee even when my bladder is empty. Cramps in my bladder/abdomen. Some dizziness and weird vision episodes.

They had me add these in a separate area - these are just the majority of what I can think of. Part 2 to my post.

Was previously on Micardis HCT; dr. switched to generic Lisinopril HCTZ 12.5 in 11/07 when I went on Medicare & was concerned about cost of Micardis. Since that time I've put on 10 lbs. and had increased pain/muscle fatigue and general lethargy. Unusual, as I've exercised 4-5 days per wk. (incl. aerobics/strength trng/flexibility.) for 20+ yrs. Also, frequently, have problems swallowing pills due to feeling of obstruction in esaphogus tube. In July '08 I awakened to slight numbness/tingling in lips and my lips then proceeded to the swell to the point of pain and my lips (in profile) protruded further than my nose. I received steroid injection and prescription for steroid pack. Diagnosis was possible allergic reaction to new cosmetic product. Today (9/3/08) I woke up with the same symptoms and again had to go to the dr.for a steroid injection & meds. Diagnosis this time (different dr.) was possible side effects of "blood pressure meds." Has anyone else experienced edema of the lips, wt. gain, and problems swallowing?

I started taking 10 mg. of Lisinopril on July 8, 2008. At first, I experienced extreme fatigue and weakness. However, this wore off after a few days. The dosage was increased to 20 mg. on July 21, 2008. I started having horrible symptoms on July 29, 2008: rapid pulse (as high as 118 b.p.m. while I was quietly reading), heaviness in my chest (which felt worse after I exercised), and shortness of breath. I had never felt so bad before in my entire life!!! I suffered with these symptoms until August 15, 2008 because I was hoping that they were just temporary. Unfortunately, they only got worse the longer that I waited. It is such a shame, too, because Lisinopril really did a good job of keeping my b.p. down.

This is the third day that I haven't taken Lisinopril, and I am feeling a little better. I am now on Metoprolol, which is helping with my rapid pulse. For those of you who experienced breathing problems while taking Lisinopril: How long did it take before your breathing returned to normal?

After doing a little internet research I found this interesting bit of information regarding Lisinopril:

Lisinopril was developed by Merck & Co. and is marketed worldwide as Prinivil or Tensopril and by AstraZeneca as Zestril. In India it is marketed by Micro Labs as Hipril. Like other ACE inhibitors, it is derived from the venom of the jararaca, a Brazilian pit viper (Bothrops jararaca).