Actos symptoms and conditions

My husband had been on Actos for 4 years. A new Diabetic doctor said h needed to get off the Actos to loose weight. So she put him on Januvia.
He takes 1000mg twice daily and 100mg Januvia once a day. Since taking Januvia he wakes up complaining that he had slept wrong on his shoulder, then he complained that his hands and feet felt like he was developing arthritis. This has gone on for 6 months. 2 days ago he woke up with both his feet and his hands were swollen and painful. I started researching Januvia and found this blog. I can't thank all of you enough for the information. None of this side effects are published by Merck!! I took my husband off Januvia and within 12 hours (checking his sugar every 2 hours) his hands and feet were half as swollen. We are headed back to the doctor to reevaluate hi medication.

My doctor decided to switch my medication from Actos (15mg. daily) to Januvia (50 mg. daily) to try to get better blood sugar levels (120-130 mornings). Took Januvia for about three weeks. After two weeks, started experiencing sleep disturbance (waking every few hours), chest pain, digestive distress (could barely eat toast and eggs), anxiety, and flu-like symptoms (muscle aches, headache) which I thought was my fibromyalgia flaring. Went online yesterday and found this website which described many of my symptoms. Never associated them with Januvia. Did not take medication yesterday and feel 95% better today. I will not take this medication again. Also, Januvia did not lower my blood sugars. In fact, morning readings were higher (140-165).

November, 2008 I started Januvia about 3 months ago while also taking metformin, glimeride. I previously took Actos but was gaining a lot of weight. Actos replaced the Avandia. The first few weeks on Avandia I seemed fine and the bs was okay. Gradually it increased along with severe painful spasms in my legs, trunk and daily in my neck. Eventually my hands began cramping. I also became severely constipated which is quite unusual for me. I then developed a series of upper respiratory infections. Since I was feeling awful I decided to research Januvia and its side effects. The manufacturer mentions the infections but not the others. As an experiment, I stopped taking the Januvia and within about 5 days, the painful leg/trunk spasms began to disappear. I'm contacting my doctor this week to find me a new drug....hopefully not insulin.

Wow. I started taking this when it first came out, a couple of years ago. I had DM w/uncontrollable BS's. BS's came down significantly. But now, a couple of years later, I've been experiencing a few night terrors, when first put on insulin and Januvia, I gained 20# and can't! get them off. I also have fibromyalgia,...so I didn't even think about the Januvia possibly accelerating, increasing, or changing what was going on with the fibro.

I get violently sick anything with Metformin, and swell up like an air balloon (gained 50! lbs. on the Avandia & Actos (MD screwed up and gave me both in maximum dose--I've had leg swelling ever since.) Anyone have any leg swelling/edema? They keep trying to put me on anti-depressants..I've had "real" depression before, and I don't have that kind of feeling, just exhausted, like I can't get going...fibro...or Januvia?

After reading a

Has anyone had hair loss? I have been on Simvastatin for 30 days adn I noticed hair loss.

Notice--if you know anyone Blind that takes the Drugs-Actos or Avandia-Please spread the word
THESE DRUGS CAN CAUSE YOU TO GO BLIND
In Jan 2000 I was prescribed 15 mil per day Actos-in a few months it was raised to 25 mil per day-in Oct 01 it was raised to 35 mil-in Aug 01 I had a light stroke in NOV 01-vision got very blurry.
My Dr sent me to a Dr of Ophthalmology, Tulsa, OK-the Dr stated, we can fix this, you got to me in time. We started Lasers, 3 treatments in left eye & one treatment in right eye, vision got worse. Now I had Cystoids Macular Edema. Shots in the eyes 2 in right & 4 in left of Kenalog.
About July 03 my medication was changed from Actos to Avandia. Since Kenalog can worsen cataracts, I had cataract surgery on left eye Dec 24th 03-it was wonderful I could hardly waite to get right eye done. Jan 04 we done cataract surgery on right eye--My vision was 20-20-BUT-only for a few days!! The swelling had come back.
On Jan 6th of this year I was watching the local evening news-they stated the F D A has put out a warning on the drug Avandia-in research, Actos & Avandia have some of the same ingredients --Could my problem be the medication?
I stopped taking Avandia on Jan 7th-I watch my blood sugar well & it is better since I stopped taking Avandia All the things that were being done to my eyes was all in vain as the drug was causing such swelling.
My vision is getting better by the day since I stopped taking, Avandia. Now my problem is all the lasers, shots & work that has been done to my eyes in trying to fix a problem I did not have.
Pat ***
If

i'm taking this medication because I'm Diabetic. Is it suppose to have me gain weight? I'm also taking Diovan and Actos since this past May and I've notice the weight gain. I've been on Glyburide and Norvasc for quite sometime and it hasn't made me gain weight. Can these first 3 medications (Metformin, Diovan and Actos) be substituted with medications that doesn't make me gain weight. I'm reaching close to 160 lbs. when I weighed 143 lbs. for the longest time and was doing good losing more.

Thank you,
Val ******

Since taking Actos I have had swelling in feet and legs, shortness of breath and weight gain. I quit taking it for a week and some of the swelling went down and I lost about five lbs. I don't want my diabetes to get out of control but neither can I afford to gain weght.

I have been on statins for 20 years. Started with Mevacor and then Lipitor 10 mg. Had a triple bypass 4 years ago and at that time my Lipitor was raised to 40 mg. I didn't seem to have any problems. About six months ago Zetia, Actos and Glucophage were added and since then it has been a nightmare. I have had general body cramping, fasciculations (twitching) in my legs, muscle pain, lethargy, atrophy of the muscles of my legs (right>left), and foot drop on the right side. Saw Neurologist and had EMG/Nerve conduction studies showing motor nerve deficit in my legs. This is the picture of ALS. I stopped Lipitor about 1 month ago and the rest of the meds about 1 week ago and everything is better (except the foot drop). Hopefully that will improve with time. The problem is that I need those meds. Anyone had problems with lipitor that then switched to another statin without problems? Anyone had problems with Zetia alone? Anyone had problems with Actos or Glucophage?
Thanks,