Adrenal insufficiency symptoms and conditions

jesus its really comforting to explore the possibility that all this unnecessary havoc is the synthroid! i have wasted the last four years in complete confusion, and utter weirdness .and frankly feel old as hell ..
ive always felt up until 5th grade, the times would never be so jolly, but the last four have been dead since my diagnosis at .75 mg; i feel like a numb, lifeless, terrified kid trying to feel something, if anything at all. I have experienced many of the symptoms below, hair loss, anxiety, extreme bipolar moods, and depression. I want to cry for keeping my mouth shut for so long and i constantly fret and worry that age twenty is killing me faster than other people for no apparent reason- im done and would be thrilled to cash in my manic depressive cynicism for a sleepy and happy soul. now i have to figure what to do next...any suggestions other than throwing the shits in a fire?

I am a 33 yr old male with Cystic Fibrosis. I started prednisone in 2006 and as of 2009 i have never been off of it.This drug has destroyed my body. I was under weight when i started, at 130 lbs. I am 5'9'' so i admit that was thin,but know i am at 170 lbs. This has had an effect on my relationship with my girlfriend since i met here when i started taking it. It may actually help me breathe better,but I am not sure. I have decided to stop it myself. I will do so slowly,but i am sick of the way i look and feel. This may sound silly to some but i just hate being in this state. I look like a pregnant woman playing a trumpet. I wonder how long it will take me to look like me again? Good luck to all of you. BK.

I'm a physician. Usually Kenalog injections can be avoided and oral steroids used like prednisone. The local dimpling effect may occur if the injection is too shallow, actually there is a temporary "disolving" of the subcutaneous tissue, the muscle and joints are not damaged. It is usually viewed as a "cosmetic" adverse effect. The Kenalog injections was primarily designed for joint injection and the kenalog or similar depo form stays active in the joint for a few weeks. All steroid medications can cause irritability and this is usually temporary for a few days. Steroids can cause muscle weakness- this is usually associated with high doses for prolonged use like being on prednisone for 3 or 4 months. Steroids can have an adverse effect on menstruation, but this is usually associated with chronic use. The most serious problems with the steroids result in bone weakness(osteoporosis) and serious damage to joints like the back and hip. Steroids can also result in weight gain, diabetes, high blood pressure and cataract formation. I don't think Kenalog is any different than other steroids such as Medrol or Prednisone in terms of the side effect profile. These are dangerous medications that can also be very helpful in saving lives and diminishing pain.

I agree, for me this is a horrible drug! This is the 2nd time my allergist prescribed it to me (last time was this past summer and I had severe panic attacks and thought I was losing my mind) this resulted in me returning back to my GP and him putting me back on Paxil (which I had been off of for a year). I was extremely reluctant to use this again but thought i might be able to manage it this time (with the help of Paxil).

My allergist prescribed Prednisone to me 2 weeks ago (5mg 3x's day for 3 days then, 2 2x's day then 1 for 5 days) I made up until the last 3 pills. I had severe brain fog and felt like I was floating through space. I couldn't even remember driving to work and parking my car! Extremely fatigued (I have diabetes (which is under control, but I had to keep checking my bg because I thought my sugar was dropping to low). Now, within the last week of taking the Prednisone I have experienced aching in my kidneys and I think I have a kidney infection.

Can Prednisone do this to you??

I am calling the doctor tomorrow. Today is the first day without Prednisone and I feel like I am totally out of it - really spaced out, dizzy, panicky and a bit nausea.

How long does it take for you to get Prednisone out of your system?

Survivors Of Prednisone
Type: Common Interest - Health & Wellness
Description: Many of those with auto-immune diseases such as Crohn's Disease are forced to go on a prescribed steroid known as Prednisone. The effects of Prednisone are terrible. Prednisone creates water retention (puffiness) in your face and torso. It causes severe mood swings. It also causes your hair to fall out. And that is just going on the Prednisone. Once you get off the Prednisone, you then have to deal with the adrenal insufficiency as Prednisone can shut down your adrenal glands.

There seems to be little support for people who have been on Prednisone. They seem to be left alone to deal with the side effects and the confusion and fear that it causes.

This is what this group aims to do:
***
Provide awareness of how Prednisone can and has affected lives.

So if you are feeling down or suffering from crazy mood swings or can't handle looking in the mirror anymore then come and let it all out !

I was diagnosed with Crohn's disease in July. I had my colonoscopy/endoscopy the day before 4th of July. Got sick with what I thought was the flu on June 26th. That's when I first landed in the hospital (dehydrated & sick). After the diagnosis I was first put on Entocort and Pentasa (Pentasa is supposed to be a remission drug - keep you from having flare-ups). Entocort didn't work so they switched me to Prednisone. I've been on Prednisone for about 6 months now. Going from 20 mg to 40 mg and then I'm finally weaned down to 5 mg. I get to go completely off of it Jan. 13th. Scared of what other side effects might occur from coming off the drug. While on it I've had emotional problems, acne(never had a problem with it before), moon face, gained 30 pounds, joint pain (I was in therapy for as long as insurance covered. - I recommend water therapy, it helps for some people as it did me), trouble sleeping (haven't slept a full night since I got sick), certain days I'm really really thirsty, I've had sort of what I'd call restless leg (I had this before I was on this medicine but it has gotten significantly worse - mostly at night or when lying down), and dry skin.I have to say though that the WORST side effect is the FOG. It's horrible. I enjoy learning and using my brain and when I'm on this I can't think, I mix up words, and it feels like my brain is covered in cobwebs.I had to drop a calc 2 class and that got me off the track I'd set with my academics. My inflammation rate is down where it's supposed to be as of the last blood test a couple weeks ago. So I guess the Prednisone and Remicade are doing what they are supposed to - but I still don't feel as if the pain (not associated with Prednisone - caused by the disease) has gone completely away even if the inflammation has gone down. And Prednisone's effects are just horrible. Some nights I feel depressed and just want to cry and cry. The past months have been trying because of several hospital stays, switching to many different doctors (gastrointernologists, nephrologist, urologist (kidney stones), primary doctor - and they think maybe I should see a rheumatologist), and Pentasa (it began shutting my kidneys down). I just hope that when I come off the Prednisone the side effects will fade (hopefully quickly but lets be realistic - ill just be happy if they go away sometime in the next few months) and I won't flare up again. Anyone know the best way to get rid of the weight? I'm already drinking lots of water and I go walking and do exercises everyday.

QUESTION: When tapering Prednisone does anyone have a place(s) on their stomach that are sunken in and feels dry compared to the skin around it?

Anyways, I hope that everyone overcomes their difficulties, whatever they might be or concern. It's hard to have a life when you are constantly fighting your own body to stay healthy.There are plenty of situations in life that are already hard enough to deal with without medical issues of your own. Best of luck to all!

I was given prednisone for the second time this year having never taken it.
1st time was for an allergic reaction to sulfa,
thought I was having a heart attack a couple of hours after it kicked in.
(I am 28)
Lost so much strength, used to go out & do 10-15 chin-ups, couldn't get to 1.
Grouchy, weepy.
That was in August.
I November (1 week before thanksgiving) I got sick with upper respiratory, same cold as rest of my family, but it knocked me out. Doctor figured it was cause of the 5-8 cigarettes i smoked at the time,
prescribed antibiotic.
Flash to 2 weeks before Christmas:
Laying on couch, unable to breath, went to doc, given antibiotic, inhaler, and Prednisone:
2 pills 2x's a day for 1st three days, then 2 pills 1x a day next three days.
I think they where 20 mg?
I was in very bad shape,
But NOW
I had tried to give up those last few cigarettes I had held on to, since I had gotten so sick.
I had insomnia, nausia, insatiable appetite, sweating, fuzzy upper lip ( i am female)
gained 15 pounds, depression, couldn't even shower unless I dragged myself through it, quit quitting smoking to try to alleviate the depression, but this is unlike anything I have ever felt.
Oh, and the reason I am up so late,
my right thigh feels like it is dying from the inside out.
It started the day after starting the meds, that was December 21st. It is now January 3, and it won't stop. I am so worn out from it.
I can't sleep.
It's like a cramp that never ever ends, but it's down in the bone.
My 3 yr old daughter put her weight against it and I screamed.
It seems like it is walnut sized, with pain radiating out from it.
I thought I might have a blood clot, my husband brought me Aspirin tonight in bed, and now I just cannot sleep,
it doesn't just hurt, it is hurting to distraction.
I feel out of my mind,
and so old.
My stomach had been solid abs a few months ago, I worked so hard on them, now, I do not have the strength to lift a jug of milk, and my tummy looks more like pizza dough.
I am 5'6" and went from 118 lbs to 135, right now back down to 127 as I cannot eat even though I am starving, I just can't.
But I am really scared about this leg pain.
I swear there is something in there, and at night I fear it coming loose in my sleep and killing me. Mind you, I am not sitting here imagining it, i am feeling this pain in what little sleep I am getting, and the dreams start.
I was on it a short time, but it was 2 times this year, within 6 months, do you guys think it is the reason?
any thing you think would help. Thanks

I was just wondering...I've been weened off Prednisone the last month or so and today is my last pill. YEAH!!!!!!!!!!!!!!!!! AMEN!!!!!!!!!!!!!!!!!!!!!.
However, I've noticed that my joints hurt and my feet oh the pain. Is this normal. I feel like my muscles are weak. walking up a flight of stairs is painful. Anyone know how long this will last or if this is something I will have to live with.

Hi guys,

I have written several replies to people on the side effects of Prednisone.

Mainly I have dealt with how long it takes for your body to go back to normal after being on it. This is because i was on it for ten years and have been off it for three and have dealt with side effects and adrenal insufficiency.

I am trying to create awareness for what people go through on Prednisone and also trying to create some support for people out there.

So I have recently created a group on Facebook called Survivors of Prednisone. For those of you who are on Facebook you might be interested enough to have a look and maybe find other people who you can share things with and know that you are not alone. Also I can answer questions if you want to ask me things.

good luck and hope to see you there,

Anne

Hello EveryOne out there...OK OK....

Now Why have I been out of touch since Sept 14th.... 2007???

I have been VERY VERY ill.....

Y'See, I went to see this new Doctor (Quack) for continued pain in my chest (sternum) area....that I have been having trouble with all Summer. (Severe Costochondritis/Fibromyalgia) By Sept 14th, this Quack who claims to be a Doctor had given me this prescription for Prednisone pills (20 mg each)....with orders to take mega doses of this toxic poison in order to combat the pain I was suffering. I was so desperate to get out of pain that I went ahead and filled the prescription and started taking the pills that eventful Friday night. I made the fatal mistake of trusting this Doctor!!!

If I had any sense God gave green apples I would have researched this a little before taking this medicine!! I would have run like all heck in the opposite direction!

I had been taking these reccomended large doses for approx two weeks back then per Doctor 'Quack's' order.... I have been hooked after the first week....and now currently desperately trying to get off of it with only marginal success!!

I have been on this Prednisone crap for some 49 days, currently and desperately trying to get off of it....with terrible side effects!! I have experienced every side effect known to the Devil himself and even discovered some new ones that I never knew was possible!? Case in point! I can't sleep night after night without terrible withdrawals all night long!!! I am forced to contend with them every night here. Not to mention I fight the withdrawals all days long too. I have this inept doctor and I am sorry I even went to him in the first place...!

The withdrawals I am now getting are harder to deal with than the original chest pain itself!!! Not to mention even eating the so-called 'wrong' foods sets off even more withdrawals almost immediately. I am now extremely sensitive to light and the sun~ not to mention.....noise....and stress....

I am much sicker from this Quack Doctor's so-called "HELP" than I ever was before....

I don't mind saying his name and trying to steer everyone away from this jerk Doctor here in Las Vegas who takes advantage of people in pain when they are desperate by feeding them toxic poisons and passing the poison off as something harmless thats gonna help them??? Just ask me who he is and I will tell you. I have no qualms about it....

Bottom line is I have spent this last month trying to get off this crap and I just found out that the withdrawals may bother me up to a YEAR after I take my last dose of this crap poison!! I have been going thru H***!!! A nightmare I would LOVE to pass onto this Quack who pretends to be a doctor!

I am down to about 7.5 mg per day now from about 180 mg that he gave me originally Sept 14 2007. Believe me this was not easy thing for me to do. I went "Toxic" on this drug weeks ago and it has affected my ability to process, think and reason properly. I feel like part of my mind is now missing or went on permanent vacation!! Dizziness,feeling like I'm gonna pass out, Brain Fog and Mass Confusion is the order for the day~depending on the time of day???

"The side effects of prednisone include adrenal suppression, which can occur with periods of prednisone use to surpass seven days. Adrenal suppression refers to the body’s inability to synthesize natural corticosteroids, resulting in a dependency on the prednisone taken by the patient. This is why doctors do not recommend the cessation of prednisone when the patient has taken it for longer than seven days. They reduce the dose gradually over a few days in the case of short-term prednisone use, and over weeks or months in the case of long-term treatment. Stopping prednisone treatment abruptly can cause the life-threatening Addison’s disease, in which in the body no longer produces sufficient amounts of adrenal steroid hormones"

I want to SUE this Doctor for making me this sick!!!!!

SDR

GRRRRRRRRRrrrrr!!!!!!!

I am 21 years old and was recently diagnosed with rheumatoid arthritis in my hands, fingers, and wrists. My doctor put my on 60 mg of prednisone at first and then had me slowly go down to 20 mg a day. I have since been trying to go off of it myself. I can't stand the side effects any longer. I have this constant charlie horse pain in my hips and legs, i am so hot and constantly flushed, i feel so depressed ( i am normally a happy all smiles kind of person ) i have done nothing but cry everyday for the past week because I just feel like so many people don't understand or believe anything I am saying. I thought maybe some of this was all in my head until I found this site. Is there any other medications out there that don't have all these terrible side effects? I feel as though the pain from the arthritis is far less worse than this.

I am a 19-year-old female pre-med student who has been taking this nasty drug for exacly 1 year now.... The amount I am on continues to change, for my disease keeps returning and leaving remission. I finally get down to 10mg from 40mg, and have to go back up when symptoms return!!! This is SO discouraging. The worst part is, no one understands the physical and emotional agony this drug brings on. I'm 19 and feel like I'm 90. My body aches, my weight is constantly fluctuating, I bruise from simply being poked (being a clumsy person, I look like I am beat!!), my bones feel as if they are about to break, and I am SEVERELY despressed. Being in college and taking rigorous classes, this is just too much for me to handle anymore... My 5-year relationship with the love of my life/best friend is falling apart because of my horrible mood swings.. don't blame him for leaving. I feel as if this drug has ruined my life more than the disease itself...Does ANYONE know if one's body and mind returns to "normal" after FINALLY being off this drug??? I pray to God the answer is yes... I would appreciate someone's reply and/or insight, because my Dr. fails to tell me about ANY side effects until I mention something. PLEASE REPLY!!!

Severe hair loss/thinning. I've been on a low dose of prednisone for 11 years. My dose varies from 5/10 depending on the flare up. Before prednisoe, I had A LOT hair on my head.... thick, curly,healthy, shiny hair. I have about half the hair left on my head that I had before. It's now dry, brittle, lifeless, and damages very easy. It's hard to get any length on hair, because as it grows, it's breaks off...it's quite thin and has been ruined by prednisone.

If ever you are prescribed PREDNISONE, please research your dosege, your condition,and your prescribing MD......wish I had.

I am a 50 year old post menopausal woman with osteoporosis. I had 3 injections over a 3 month period for degenerative disc disease (cervical). Last injection was done 1/12/07. I was not warned about increasing osteoporosis as a side effect of this medicine even though they knew I had it and was taking medication for it.
I experienced the following side effects:
extreme sweating around head, neck, and torso
extreme mood swings where I actually became violent (I'm really a passive person), hitting loved ones, throwing and breaking things (completely out of character for me, in fact I've never behaved in this manner)
extreme depression where I tried but failed to commit suicide (I was hospitalized in a psychiatric facility for 9 days)
huge face
huge hump on my back
I now have extremely high blood pressure (was normal before)
I experience confusion and memory loss (sometimes I'm in the middle of a sentence and forget what I'm talking about and I am normally a pretty sharp person.)
I now have adrenal insufficiency and am currently scheduled for an MRI of my pituitary gland next week so they can figure out why my adrenal glands are no longer producing natural cortisol.

Went to see the doctor who gave me the injections about these side effects (before the suicide attempt) and was told these side effect would go away in 3 or 4 days! He gave me a prescription for 5mg valium and told me not to eat so much!

After my stay at the psych facility I again called the doctor who gave me the injections to try to find out if the injections had caused all of this. This doctor would not order any tests but thankfully his nurse (behind the doctor's back) told me to call my primary doctor and explain the situation and ask for a cortisol level test. My cortisol level was so low that I got an appointment with the best endrocrinologist in town the next day.

I am currently on a prednisone taper to try to stimulate my adrenals to produce the correct amount of cortisol.

Has anything like this happened to anyone else? I am so angry with the doctor I want to sue him but I'm sure I signed something protecting him.

I have been reading the posts with great interest, and as a frequent prednisone flyer, I have a Canadian perspective that may or may not be helpful. (Please be patient as typing and prednisone don't mix with me :>)

But back to the point. During my years of prednisone useage, I have always been told that long term prednisone use shuts down the adrenal glands, not enhances it. Which is why after a period of two weeks,(the time it take for them to shut down approximately, continued use of prednisone takes over what the adrenal glands formally did. (ie. regulate metabolism, and provides resistance to stress; ie. temperature extremes, high altitudes, bleeding, infection, surgery, trauma, dental work and good old stress. It also has the bonus of raising blood pressure if and when a body needs it.) A lot of the side effects I have read come from the prednisone directly, and indirectly from non-functioning adrenal glands. Furthermore, we are told it takes roughly a year (sometimes longer), for full adrenal gland function to come back, and why, if during this time you do need surgery, dental work, or get an infection, or in an accident, it is not uncommon to have to go back on the prednisone until the 'stress' is fixed. The symptoms of low pressure (feeling faint, sweating, dizzy etc.) is usually the first sign that the adrenal glands are not working at full capacity yet.

Knowing all of that, I sincerely wish I had known that if one is depressed, anxious or suffering from panic attacks prednisone compounds the emotional problems greatly. Or
simply creates them as side effects. If you have existing psychological difficulties, sleeping 2 hours in 24, massive, unpredictable mood swings, (for me it was not so much mood
'swings' per se, more like bad, worse, and would someone please put me out of my misery.) For me, I know prednisone turns me into a 'speedfreak'. I can't sit still, can't talk, walk or smoke fast enough. I was very lucky after a stressful last year, and taking 50 mgs of predisone for 4 months, when I finally crashed, I spent 6 weeks in a psych ward basically to
contain me until I had been weaned off of the prednisone. (Ironically enough, it was a year ago tomorrow when I was hopitalized.)

So today I started taking 50 mgs of prednisone, and can already feel my heart and pulse rate excelerating. Fortunately, I no longer have the emotional distress, but during this summer I developed edema (45 pounds in a month), and high blood pressure. Both the doctor who prescribed it and the pharmacist who fill it assured me prednisone does not affect either. It only took about a minute and a half on the 'net to find out that wasn't true, (Everyone who already knew that feel free to giggle and roll your eyes a bit) after spending months working on getting the edema/HBP under 'reasonable' control. (At this point, I eat pizza and my eyes go blurry.) In closing I would be curious if any other readers have edema and/or high blood pressure before taking prednisone, and if/how much/in what way your experience has been in mixing the two.

Thank you.

I have been on Prednisone for 3 years now (adrenal insufficiency). With my Dr.'s advise I have been able to get down to 1 1/4mg. This past week I am trying to reduce again. This time I am alternating days with 1mg then 1 1/4mg. So far it is really hard. I just feel so sick. Nauseous, low blood sugar, out of breath etc.
Today was a 1mg day and I had to take the extra 1/4mg to function. Are there any tricks to getting through this and how long does the adjustment take.
Thanks for any info