Adverse events symptoms and conditions

i am 41 and i had been taking Singulair off and on for a few years. i had noticed that something was different about me but never related it to the medication. i always had a sinus infection every year, i stated having headaches and really depressed and didn't understand why. i stopped taking the medication and went and got me some Zyrtec and i have been doing just fine.

I copied and pasted the Adverse reactions below from drug.com...how is it that they list all the side effects we are all having but when i look through the mirena brochure none of this is listed....sounds a little shady huh?

Adverse Reactions
The most serious adverse reactions associated with the use of Mirena are discussed above in the WARNINGS and PRECAUTIONS sections. Very common adverse reactions (>1/10 users) include uterine/vaginal bleeding (including spotting, irregular bleeding, heavy bleeding, oligomenorrhea and amenorrhea) and ovarian cysts. Other adverse events are listed below using MedDRA (9.0) terms. Adverse reactions reported by 5% or more of clinical trial subjects include:

Abdominal/pelvic pain

Vaginal discharge

Nausea

Headache

Nervousness

Vulvovaginitis

Dysmenorrhea

Back pain

Weight increase

Breast pain/tenderness

Acne

Decreased libido

Depressed mood

Cervicitis/Papanicolaou smear normal, class II

Hypertension

Other relevant reported adverse reactions occurring in less than 5% of subjects include: migraine, vomiting, anemia, dyspareunia, alopecia, eczema, pruritis, rash, urticaria, abdominal distension, altered mood, hirsutism, edema.

I have been on this for 6 days for a UTI. I personally am not allergic to sulfa drugs and have had absolutely no problem while on it so I can't speak to specific side effects but I do have something to say about it. I'm a little confused as to why so many of you believe that this drug should be taken off the market. Surprise, a lot of people are allergic to sulfa drugs which accounts for the vast majority of adverse events described by nearly everyone on this post. And guess what, every single drug comes with side effects (Tylenol, Advil, Tums, etc. are no exception) and you accept the risk of those side effects when you put it in your body and weigh that risk against the possible benefits. It's not your doctor's or the drug company's fault you're allergic! Antibiotics, including this one, have saved millions upon millions of lives. It seems intuitive but it evidently must be said: if you're allergic to it STOP TAKING IT and call your doctor so he can prescribe a different antibiotic. Seriously people, it's not rocket science. Hives are a pretty straight- forward symptom of an allergy and one that can be diagnosed by the lay person. I am a medical professional, but even if I wasn't, you don't need an MD behind your name to figure that one out. Why would you continue to take it after having an obvious reaction? (a reaction that, by the way, is a well documented, clearly stated possible side effect of this particular medication if you'd taken the time to ask any questions whatsoever regarding your own health, not a surprise adverse event of a bad drug) It's not rocket science, it's common sense people. When I'm prescribed something I'm not familiar with, my first question is, "What do I need to know about this." Even after a satisfactory explanation, I look it up before taking it. In fact, that's how I found this post. Which brings me to my last point, why is it that people blindly put things into their bodies that they know nothing about. If the pharmacist doesn't explain drug information to you in person, that's what the little drug safety pamphlet attached to your Rx is for. Read it, that's why it's there. OR, there's always the option of using this wonderful resource called the internet. Use your brains for god sake and take a more active, responsible, and informed role in your own healthcare process. You are ultimately responsible for your own health, and to be completely honest, you're one of the only people who actually cares about it (guess what, your doctor probably isn't one of them because he has a hundred other pain in the ass patients with no common sense to keep track of). Think people...

My daughter is a 4 year old child started on Singulair after she was unable to tolerate Zyrtec. For the first few days her allergies seemed better and we were encouraged by her improved allergy symptoms (allergies to poplar trees, grass, and lambs weed manifest as headaches, itching (usually of the extremities), and stomach aches). However, after 2 days her behavior became increasingly erratic. She was emotional, tantrum prone, irritable, anxious, and had difficulty sleeping although she appeared and said she was exhausted/tired. After several weeks on Singulair, we stopped the medication to determine if it was causing the behavioral and sleep problems. The symptoms stopped after discontinuing Singulair and she went back to her usual happy, well behaved self. After being off of it for several weeks we decided to try it again due to her allergies flaring up and wanting to be sure it was the Singulair causing the behavioral problems (because for all of its negatives, the greatest positive about Singulair is that it definitely helps her allergy symptoms). Unfortunately, the irritability, anxiousness, tiredness, tantrums and insomnia returned. We tried giving it to her at different times during the day but the symptoms were still present (although she slept a little better when we gave it to her in the morning). We also tried cutting the dose in half and giving it to her around noon. Decreasing the dose did help with the symptoms to some degree, but they were still bad enough to outweigh the benefits of taking the drug. As a nurse, I love Singulair for the relief it provides allergy sufferers...unfortunately for my daughter, the side effects outweigh the benefits. Given the rates of ADD, ADHD, and other behavioral problems diagnosed in children nowadays, I thought it pertinent to report these symptoms present in my daughter that are solely caused taking this medication.

I, like all of you, had terrible side effects related to Mirena that are NOT listed in their product insert... thus not known to our doctors who often dismiss our symptoms. However, these NEED to be reported to the FDA. I urge all of you to report your adverse events associated with Mirena at:

https://www.accessdata.fda.gov/scripts/medwatch/medwatch-online.htm

One voice may not make a difference, but our voices combined can. Don't let anyone else suffer like we have...

I go by the ID Miserable Knees. I posted last spring on medications.com about my adverse reaction to Levaquin. I was given a 10 day prescription for a respiratory infection. 3 days after I finished taking Levaquin, BOTH KNEES were swollen, painful and I could barely walk. I spent a month throwing myself backwards into chairs due to the inflammation in my knees. My knees were on fire, I was in pain every day. After seeing an orthopedic doctor an MRI showed cartilage damage. A year later, I'm living with permanently altered legs. I was an avid walker, loved to hike, would spend hours walking for recreation. Levaquin changed all of that. I had a career requiring me to be on my feet for 12 or more hours a day. Levaquin changed all of that. I decided, if this could happen to me, it could happen to anyone. Now, there is a documentary about the dangers of fluoroquinolne antibiotics. When I was harmed by Levaquin, I was flabbergasted that something like this could happen to me in the prime of my life. I made this 52 minute film for all of the people like me who trusted the system, (government, doctor, medicine) to guarantee my safety. "Certain Adverse Events" is the name of the documentary and it is now available online. You can reach the documentary site by going online to the .com of "Certain Adverse Events"

Miserable Knees Productions

I URGE YOU TO PLEASE SUBMIT ANY ADVERSE EVENTS OF THIS TERRIBLE KENALOG DRUG TO THE FDA--JUST CLICK THIS LINK AND COMPLETE THE FORM: http://www.fda.gov/medwatch/. The FDA is responsible for assuring safety of medications. Therefore, it is imperative that the FDA recognize the adverse effects to provide any credibility to a class action suit. Please consider forwarding your case to the FDA to force them into action and begin addressing these atrocities. Here's my case: I am also a victim of having the Kenalog injection administered over a year ago to alleviate poison ivy itching symptoms. Prior to having the injection, I was not informed of any side effects. Not only did the injection not alleviate the symptoms, but has resulted in a discolored and uncomfortable indentation in my left buttock area and psychological anguish because of disfigurement of my body. It is over a year later and the indent remains and continues to cause discomfort. The dermatologist who administered the injection stated that there was nothing I could do to reverse such effects. I reported my case to the FDA (Food and Drug Administration) Med Watch and strongly urge others to report their adverse event to the FDA (see link above).

Lupron is a dangerous drug. There are over 10,000 adverse events reported to the FDA about this horrible drug. It causes significant bone density loss and many, many other horrible long lasting side effects. Check out the FDA website for yourself. This drug controls the release of estrogen, which is vital for all body functions and brings your estrogen levels dangerously low. Check out the Center for Endometriosis Care in GA or The Center for Advanced Laparoscopic Surgery in NY or Dr. David B. Redwine in Bend, Oregon. This drug was originally approved in 1985 for the treatment of advanced prostate cancer. It is a highly toxic drug!!

I'm 43. Started taking Singular about 10 years ago. I think that's when it came out. Over time, I've developed panic attacks, mild depression, mood swings, panic disorder, muscle twitches and cramps, and agoraphobia. I finally slowly took myself off of all medications after doing The Allergy and Asthma Cure - a great book and it helps tremendously!

After being off of the Singular, my symptoms listed started going away. i stay have agoraphobia because that's a learned issue from fear of having a panic attack. All doctors and pharmacists say there's no link. I know lots of adults who have gone through this only to get put on Xanax and antidepressants. Try to go as natural as you can. All of these meds have fried my body. Diet is huge to! I've substituted goat's milk for cow, Try it!

To get the real information in regards to what level of research that is going into this investigation is.go to the Institute for Safe medicine practices click on Quarter watch.
To people like chris555, I believe you are engaging people for sport and say very hurtful things,your day will come and it may just be in the unemployment line.I can only imagine that you must work for Merck or you would not feel so threatened by the good that has come from Parents advocating for their childrens safety.I want you to know, that all who knew our family and our child understand what took place and our reasons for trying to get the proper information where it should have been," on the label". When our child died no one knew about all the added side effects from post marketing reports,which is "a reliable way to track a drugs adverse events".Maybe you should do more research on the legitimate information of causal relationship. Don't be so afraid of a possible drop in revenue for the drug company that I believe you might be an employee of.K. M.

My 6 1/2 year old daughter has been on Singulair for 3 1/2 to 4 years now and we have had horrible experiences! She was having night terrors, mood swings, angry issues, self control issues, crying over small things, etc. We have been to psychiatrists and psychologists who have diagnosed her with mood disorder, sensory processing disorder and anxiety disorder! Well she has recently been having stomach problems so we have been going to a GI to figure that out. I got online to research and found numerous sites that told how Singulair causes all these things in children. We took my daughter off the meds and within 3 or 4 days seen a tremendous difference! She is a totally different child! It just really frustrates me and saddens me that all these children and their families are going through all this and the doctors do not seem to care. The allergist or psychiatrist didn't believe me. They say no study has ever proven such things. I don't care what they say we as parents know our children and we are the experts when it comes to seeing how they change when on this medicine, we are the ones that live with them and are with them everyday not the doctors! I think they just don't want to lose out on their money from prescribing this drug 90% of children with allergies and asthma!

To clear up any misunderstanding about the FDA Singulair investigation.
FROM THE FDA STATEMENT ABOUT THE SINGULAIR INVESTIGATION

"FDA has not yet reached a definitive conclusion regarding the clinical trial data on mood and behavioral adverse events associated with montelukast, zafirlukast, and zileuton."

"although (the clinical trial) data do not suggest that montelukast, zafirlukast, or zileuton are associated with suicide or suicidal behavior, these clinical trials were not designed specifically to examine neuropsychiatric events. As a result, some events may not have been reported."

The FDA is continuing to investigate a link between Singulair and suicide .
They stated that they have not "closed the book on suicidality". Any news reports stating there is no conclusive link are incorrect.

30 seconds after i received my injection i felt like i was going to pass out. I also felt like i was going to throw up. I advised the front desk they ran and got my doctor.she came and got my baby and carried him to the back for me and i laid down for a few min. I feel fine now but I have always been great with shots so I figured might as well have it insurance pays for it. I thought it was very strange, she said thats a common reaction???? I asked if there were side effects before the shot and she sad no.

THE P.ORANGI REPORT
VERY VERY VERY ANGRY.
THE FOLLOWING IS AN abbreviated EXTRACT FROM MED SAFE NEW ZEALAND.
A watching brief for health professionals from the New zealand goverment's web site called MEDSAFE. I assume our equivalant of the FDA.
The centre for Adverse reactions Monitoring (CARM) is receiveing an increasing number of reports of psychiatric reactions occurring with statins, fibrates and ...ezetimibe. ...... aggressive behavior, memory impairment mood cognitive sleep and perception disorders. In Australia 9 cases of depression 3 cases of depressed mood ....... with ezetimibe use ..... onset happened within 4 days in 7 of the cases.

This reminder goes on to STATIN REMINDER to PRESCRIBERS of myopathy rhabdomyolysis and interactions.

In my small town this last week alone I have personally met 4 statin sufferer's. The last one yesterday was a charming wonderful 79 yr male, who could not see or hear properly, was aggressive to his wife and having hallucinations so severe in his words "I was to f'n scared to go to bed at night and wanted to leave (sell) his house. He stopped his medication (Fiblap 200 mgs) and the hallucinations stopped his other problems are improving.

It is now very obvious to logical people that not just statins but most cholesterol lowering medicines cause an extremely unacceptable amount of cruel dangerous adverse events. It is also very clear and almost undisputable by the statistical and very definitely UNDER reported number of these adverse effects that unnecessarily interfering with the body's cholesterol is extremely dangerous to all of us.

I can right at this moment show 3 middle aged men who are a complete danger on the road - their memories are completely shagged, they are agitated, not remembering simple landmarks and they are driving.

We have pilots in the air on this stuff, I would rather my pilot was on cannabis than this this shocking stuff.

Mr and Mrs prescribe it is you that are NOT reading the instructions it is you that are criminally negligent when the presentations are given to you and you fail as the safe process of elimination to cease this medication to your patients.

We the younger middle age are accepting of evolution, the trial, error and mistakes made in the pathway to achievement. Their is no shame in error, error in develpoment aids development and the end result.

BUT Messer's prescribes your negligence in failing to report adverse events, failing to take notice of your own government's warnings and consequently destroying the quality of life of society's grandparent's golden years is shameful and criminal and you can expect little sympathy as this debacle is inevitably exposed.

My own case in brief over a 5 year period shut down my weeze pooze and manhood. Gave me excruciating pain in every joint muscle and spasming eyeballs. Rashes, itching,muscle spasms, tremors. Insanity stopping a car and smashing my walking stick over the roof with a lady inside, hearing voices and stalking the house with an axe, being sexually suggestive to elderly lady customer, abusing customers, wife mother and friends. Driving with no recollection of towns I'd been through. Leg muscle cramps that dropped me. Decrease eye sight and hearing, when swallowing the food going down the wrong pipe. Unable to speak coherently, crying, hugging people in a special needs manner, selling my cars (2) for fear of failure of a warrant of fitness. An unnecessary hip replacement, that had me on a crutch for 6 months and 18 months later still severely limping and unable to lie on the THR side (weaken muscle). I swallowed almost 3000 pills in a 6 month period. Terrifying hallucinations, sweats that soak the bed. Completely unable to think, unable to print my own name, unable to remember neighbors names etc etc etc. Burst out in a totally deranged fit of laughter in a solicitor's face in the swimming pool changing shed. Obscene language in places where I never in my life used before To scared to go to bed at night for hallucinations and my heart stopping. Unable to keep up with my 6 yr old mate on our push bikes Almost 12 months since ceasing statins I have All the same problems though substantially reduced, I still need oxycontin, predisone coq10 fish oil. I am embarrassed about going out because of what I have done and because I'm still scared about what will come out of my mouth. I still blackout and "whiteout" (I know what is around me but I can't speak) I still have micro hallucinations and loose touch with reality.

DRUG COMPANIES, you have bought us fantastic medicines thank you. We know with development there are inevitable failures so why not own up do not cover up. The oxycontin makers and their directors were fined in the millions for their misrepresentions and they weren't giving a "safe preventitve" drug to airline pilots that are now known to cause mental impairment.

CHILDREN of the elderly, check your parents overall health, memory agitation aches and pains etc since starting cholesterol lowering medicine. Check whatever and all symptoms they have suffered since starting cholesterol lowering medication. If you are suspicious respectfully ask your doctor if your parent as a process of elimination can cease the medication for a while. Two major hassles are 1) We are not aware these adverse effects are happening to us or we may blame another cause, old age etc 2) Like me there is no way I was prepared to stop my medication, even though i knew I was dying, until I got my "TRUSTED" doctor's ok. I would never interfere with my mums meds.

TO OUR DOCTORS in our society, dog people, school groups, all clubs, trades, lawyers and even sick p*****s all have access to a data base of events that interest them but you don't. In todays easy communication society with a computer on your desk your are unable to readily access current helpful information. Shame on you.

TO MY DOCTOR, Over 3 years I complained of severe upper leg muscle cramps that made me squeal and dropped me, I complained of excess tiredness, I complained of loss of muscle power, you witnessed me in a trance in your surgery, you witnessed me 6 months on a crutch after a THR, you witnessed me with notes in your surgery (memory), you witnessed me loose my ability to talk and humor properly. I caught you red handed on several occasions not reading lab results and letters from other health professionals, you witnessed, stood up behind your desk and took off my hunched ape like stance. You completely ignored at least 2 med safe warnings I asked you for an apology you held your bunched fist in my face in your surgery and told me I was an ungrateful c&*t and to get another doctor. I wrote to you in my deranged state offering you forgiveness and hoping for medical help, you ignored that letter. When I started "sobering up" 6 months later I called you and told you of my insanity whilst under the influence of statins. You told me to tell another doctor or a medical specialist. I told you I would publish these events - you told me to go ahead. Doctor . . . . . my wife and I did not only like and respect you, I had a very grateful "love" for you and your staff. When I asked you for an apology and wrote to you, had you been reasonable and a little sympathetic to my life threatening condition, I would have warmly embraced you, forgiven you and been grateful that others would be safe. When I phoned you several months later, had you have been humane, though difficult, I would have done my best by you and society. Doctor ..... you had 3 very sincere approaches that you declined. Well bud do I know of others or not? Audit all your patients for their safety now. You told me to publish, well Doctor . . . .you may now become internationally famous. Do you think I will put a complaint to the Health and Disability commissioner where they will on proof order an apology - I don't think so, you have had 3 genuine chances for an apology. Did you report my severe adverse event to CARM? Doctor . . . . . I do not think this is conduct "unbecoming" I think it may be crime.

I sincerely wish I had never become "responsible" for my health. Given this web site, the victims I personally know, my own tragic events with statins, I now firmly, sanely and sensibly believe that JIM BEAM BOURBON and ROLL YOUR OWN CIGGIES are far more deserving of a heart foundation tick than statins.

This medications web site has saved the quality of life and indeed the lives of many people. Please take the time on the contact us to send our friends at medications an email with 4 wordS only " THANK YOU ALL VERY MUCH"

Signed Mr P. O.

PS To the police and lawyers in NSW Australia where the tragedy of the fellow who chopped his wife and grandchildren took place, please check whether he was on this medicine. My heart goes out to him and his family

PPS I DO NOT UNDER CIRCUMSTANCES wish to be contacted by anyone, with the sole exception of any authority, whose sole purpose is to benefit mankind, over this matter only, I wish to rebuild 5 traumatic years of painful destruction quietly with my family.

PPPS Any pilots in any country please forward this site and medsafe nz to your medical examiners.

PPPPS Prescribers COQ10, ubiquinol not the cheaper ubiquone, oxycontin, prednisone, large quantities of fish oil, vit C, time and patience are the only things that have been of aid. After almost 2 years on oxycontin, I have no hankling for it, I have built a resistance to it and I am now trying miniscule amounts of cannibis (I am filthy angry that I have been put in this situation) to replace the oxycontin. The fish oil calmed my agitation, the coq10 reduced pain by about 20% increased energy by about 20% 3 x 100 mgs a day, The fish oil and coq10 together stopped all irregular heartbeats showing in my BP meter. The vitamin c 6 x 1000 mgs through the day within days put pressure back to the urine and aided bowel movements.

I URGE YOU TO PLEASE SUBMIT ANY ADVERSE EVENTS OF THIS TERRIBLE KENALOG DRUG TO THE FDA--JUST CLICK THIS LINK AND COMPLETE THE FORM: http://www.fda.gov/medwatch/. The FDA is responsible for assuring safety of medications. Therefore, it is imperative that the FDA recognize the adverse effects to provide any credibility to a class action suit. Please consider forwarding your case to the FDA to force them into action and begin addressing these atrocities.

Here's my case: I am also a victim of having the Kenalog injection administered over a year ago to alleviate poison ivy itching symptoms. Prior to having the injection, I was not informed of any side effects. Not only did the injection not alleviate the symptoms, but has resulted in a discolored and uncomfortable indentation in my left buttock area and psychological anguish because of disfigurement of my body. It is over a year later and the indent remains and continues to cause discomfort. The dermatologist who administered the injection stated that there was nothing I could do to reverse such effects. I reported my case to the FDA (Food and Drug Administration) Med Watch and strongly urge others to report their adverse event to the FDA (see link above).

My 18 yr old daughter has been on singulair for several years and has complained this week of numbness in her feet and toes. I have told her to stop the drug. Is this a reversible side effect? Does anyone know if there is anything else to do?

One more thing:

It is imperative that you file an "Adverse Events Report" with the FDA. Insist that your or your child's doctor does as well. Doctors are NOT mandated to report adverse reactions of a drug to the FDA. The system is currently voluntary.

I think this fact is part of the reason it has taken so long for the truth about this medication to be revealed.

Also report your "Adverse Events" directly to Merck, Singulair's manufacturer. I believe drug companies are REQUIRED to report to the FDA.

I am wrong about these facts, somebody correct me please.

I just wanted to be sure you all read the directions in the pamphlet that they give you when you get the IUD....here they are in case you forgot to read the fine print.

ADVERSE REACTIONS
The most serious adverse reactions associated with the use of
MIRENA are discussed above in the Warnings section. Others are
presented in the Precautions section. Other adverse events reported
by 5% or more subjects include:
Abdominal pain Upper respiratory infection
Leukorrhea Nausea
Headache Nervousness
Vaginitis Dysmenorrhea
Back pain Weight increase
Breast pain Skin disorder
Acne Decreased libido
Depression Abnormal Pap smear
Hypertension Sinusitis
Other reported adverse reactions occurring in less than 3% of
patients include: failed insertion, migraine, vomiting, anemia,
cervicitis, dyspareunia, hair loss, eczema.

My 3 years old daughter was on Singulair for 8 months, that was prescribed by her Pedestrian from the Asthma clinic in Canada, Quebec. Lately, some of the symptoms of adverse effects are surfacing in her, including depression, action very emotional, constant having bad dreams (which causes tiredness), crying almost whole day in the daycare, refusing to eat and drink, refusing to join her favorite activities... Her Pedestrian told us there is no side effect on Singulair when she renewed the prescription 2 days ago. Because of my doubt about that, I started research on the web and found out that the early communication was issued by FDA. Of course, I took my daughter off from Singulair right away.

I work in the drug development clinical research field. I know that nothing the FDA or Health Canada will pursue until a lot of cases on adverse events (side effects) reported to them. Please everyone, if you or your child has had developed any side effects on this particular drug (Singulair), please report to FDA at once. It got me so upset is that this drug is constantly and widerly prescribed to children, and the Pedestrians are not caution enough to tell the parents. I definitely do not want to see other children suffer the same symptoms as my daughter had.

Hello everyone. I have had my mirena in for 2 years now and have absolutely no desire for sex at all. I decided to google the Mirena side effects to see what I could find and this site came up. Let me tell you all your story sound just like mine, but the one symptom that I haven't seen is having symptoms similar to Lactose intolerance or Gluten intolerance. I did find this ****** website and it specifically states "Glucose Tolerance
Levonorgestrel may affect glucose tolerance, and the blood glucose concentration should be monitored in diabetic users of Mirena ." Now I am not a diabetic, but my family Dr. said that I had all the symptoms of being Glucose intolerant. I was tested and came out negative. Also all my symptoms increase the longer I go with out a period. I usually go 2 months without, as soon as I have it it is like my body come back to normal for a week.
Now my husband is all about permanent solutions, so I told him that I was ready for a more permanent birth control. snip snip. I am planning on having mine taken out this year. I just want my body back.

Oh this website that I have attached is the actual Official FDA information sheet that we don't get to see, but the doctor does. Make sure you read the adverse reactions. Here they are so if you don't get to the website.

Adverse Reactions
The most serious adverse reactions associated with the use of Mirena are discussed above in the Warnings section. Others are presented in the Precautions section. Other adverse events reported by 5% or more subjects include:

Abdominal pain Upper respiratory infection
Leukorrhea Nausea
Headache Nervousness
Vaginitis Dysmenorrhea
Back pain Weight increase
Breast pain Skin disorder
Acne Decreased libido
Depression Abnormal Pap smear
Hypertension Sinusitis

Other reported adverse reactions occurring in less than 3% of patients include: failed insertion, migraine, vomiting, anemia, cervicitis, dyspareunia, hair loss, eczema.

******

I am also experience hair thinning while on Wellbutrin. I have had blood tests and there is no other detectable cause. The dermatologist said that she was only able to diagnose as possibly hereditary. However, I began noticing it shortly after starting 300mg of Well XL and then noticed increased thinning when I went up to 450mg. I don't take any other medications at all.

I searched the Wellbutrin prescribing information (a pdf on the official Wellbutrin website) and this is all I can find:

Other Events Observed During the Clinical Development and Postmarketing Experience of Buproprion

Adverse events for which frequencies are not provided occurred in clincial trials or postmarketing experience with bupropion. Only those adverse events not previously listed for sustained-release bupropion are included. The extent to which these events may be associated with Wellbutrin XL is unknown.

Skin: Rare was maculopauplar rash. Also observed were alopecia, angioedeme, exfoliative dermatitis and hirsutism.

----------------

Alopecia is hair loss. All that means is it was reported and they didn't do a study that would have produced data with which they could measure the likelihood that it is a Wellbutrin side effect. In other words, people said they were experiencing it but they can't confirm it.

I just dropped down to 300 mg and I'm contacting my shrink about tapering off completely - I feel like dealing with scalp showing through and feeling horribly self-conscious and unattractive because of it is not going to help my depression and self-esteem issues any.

I'm a woman by the way - the number of reports of hair thinning in women seems significant to me. I have no family history of thin hair on the female side that I know of.

My nephew is 7 and has been on Singulair for probably 4 years. His symptoms developed over time but recently have exploded. He has epilepsy so most of the things that he has experienced has been blamed on that. However, today his doctor took him off singulair and said he believes his symptoms are caused from the drug. He started having head drop seizures, fell out of his desk and cut his face one day. He has also been depressed, had severe anxiety attacks for the past 8 months. Several months ago, he started having such severe nightmares that it is almost impossible to get him to go to bed and go to sleep. Recently he began "seeing dead people" and "monsters" that we trying to kill him even when he was awake. He has also cried many nights with leg cramps and severe stomach pain. I will update this page in two - three weeks to let you know if these problems go away now that we have stopped the singulair.

Unfortunately my lawyer told me that they do not want to take our case because of the lack of evidence that Singulair has caused our daughters problems. :(

Does anyone out there have a pending class action lawsuit that We may be able to get in on? I have tons of proof that Singulair has caused our daughters problems and loss of almost 5 years of her elementary school career!

My phone number is *** and my email is ****** if You email me please put "Singulair" in Your subject line so I know it pertains to this posting.

Thank You in advance,
Chuck & Brenda
Jamestown New York

Here's a way out theory about my unique and to me mystifying medical situation....

I recently read where Singulair, an asthma medicine, is suspected of causing suicides, obviously an effect on the brain function. The FDA notes that over the past year, Merck has updated Singulair's prescribing information and patient information to include the following post marketing adverse events: TREMOR (March 2007), (April 2007), suicidally (October 2007), and anxiousness (February 2008). (the tremor highlight is mine since this is a major symptom of Parkinson's )

Well, I took Singulair from 1998 to 2004 and I wonder if maybe, just maybe Singulair could be a contributing factor to my strange Parkinson's but not Parkinson's problems that is
gait,
balance,
freezing of gait problems

Any thoughts or ideas on how I might follow up on my hypothesis?