Adverse side effects symptoms and conditions

I have been on Quasense for over a year and have not had any adverse side effects. I think it is wonderful.

hair loss, neuropathy in my right leg, complete exhaustion, numbness and tingling, stabbing pain in my back that wraps around my chest, headaches, depression, paranoia, stomach pains, chest pains, tremors in my head, pain down my neck, pain in toes, blurred vision, tearing pains in feet, very weak, moody, pain in face, really bad symptoms week prior to period, cracking sound in joints, -- Have had symptoms for three years and just had a neurologist confirm today that all of these problems have been caused by my doctor prescribing avelox and prednisone!

I had my Mirena removed 10 days ago. My Dr. put me on BC pills temporarily(Loestrin 24) because I had also opted to have the Essure Procedure(permanent birth control) 4 days post Mirena removal. Even with the removal, the new pill and the Essure in 10 days I still feel so so much better since the Mirena was removed. I have so much more energy. My acne and eczema seem to be improving. I think it is going to be a long process to feel "normal"again, lose the weight, etc... but I highly recommend having the Mirena removed if you are having serious adverse side effects...regardless of what your doctor says.

I have posted a couple of times previously about negative side effects, i.e. migraines, weight gain, acne, chin hair, eczema, lower back pain, no sex drive...and the list could go on. As a mature 36 year old woman I have educated myself over the past couple of years and can really only attribute all these issues to having the Mirena inserted 4 months after the birth of my daughter 3 years ago. Although at this time my doctors will not openly acknowledge these side effects, I am confident that one day they will. I encourage women to report adverse side effects to the FDA. It onlt takes a minute or two. Who knows, it may be the hormones or it may be the silicone plastic? It has to be something. It should also be acknowledged that some women, my very best friend for one, have had wonderful experiences with the Mirena. I really think it may just depend on the woman and her own body. I am having mine removed tomorrow after researching all of this for about 8 months. All I can say is, thank goodness. I am also scheduled for the Essure(permanent birth control). Food for thought for the older women in the group. Whatever each of you decide, realize you are not alone and you do not have to continue to feel the way you do if you believe that the Mirena could be making you feel so bad. Take care.

Oh Mirena..... how i wanted you to work so badly.... But alas, you have failed me.

I got the Mirena IUD inserted in February of 2009. The insertion was terribly painful, but my doctor had warned of that since I haven't had any children and I would have a smaller uterus than women who had. The pain and nausea caused by the insertion went away within 8-12 hours. For the first three months, it did everything it was supposed to do: normal periods, no weight gain, no (new) mood swings, effective contraception... Beginning on day 1 of the fourth month, things went crazy. I have had 10 periods in 6 months, some lasting about 8 days and starting again 7-8 days later. I had a two day long migraine (I've never had one before this). I have been unbelievably moody, have experienced an extremely decreased sex-drive, bloating, exhaustion, the list goes on.

So when I couldn't take it anymore, I went to the doctor and the strings were no where to be found. Then I went for an ultrasound and sure enough, the Mirena had relocated itself between my cervix and rectum........... Not to mention, there's a 4.5cm cyst on one of my ovaries. The next step is a laparoscopy (procedure where the enter through the belly button) to retrieve the Mirena and check out the cyst.

I thought Mirena was going to be such a dream, but it's turned out to be a nightmare. I never had any adverse side effects from the pill in the 6 years I used it prior to Mirena and now I wish I had never switched. I know people that it's worked for without trouble, but unfortunately I was not that lucky. Like most of you, I had researched more than I felt necessary and read all the negative side effects others experienced, I just hoped that wouldn't happen to me. I'm not telling anyone not to get it, I would just advise that you don't switch to Mirena if you have something that is working properly. It's simply not worth it (financially, physically or emotionally).

I felt it was extremely important that I make a post regarding my experience with Mirena so that it might help other women in a similar situation. I had Mirena inserted for the first time in the spring of 2007. The first few months I had some pretty intense periods, but this declined and then my periods disappeared completely. I was so happy with the Mirena, couldn't say enough good things about it, and was shocked by the numerous posts by women reporting nightmarish side effects. I had the Mirena removed just under two years later because my husband and I decided to try to get pregnant. That route didn't work for us so I had the Mirena replaced in the beginning of July 2009. The MOST IMPORTANT part of this post is that I had numerous nightmarish side effects the second time around with Mirena even though I had no adverse side effects the first time. I had morning sickness like symptoms complete with vomiting during my periods, migraines, hair loss, and severe mood swings - to the point of being suicidal or homicidal at times. I had to stop listening to the radio while driving for fear that a love song might come on and I might start to cry so hard that I wouldn't be able to see the road. I started to obsess about killing myself - triggered by the littlest of things or nothing at all. It took me what seemed like forever to make the connection to the Mirena - especially since I had no adverse reactions the first time. I called my doctor to make an appointment to have it removed only to be told it would be weeks before I could get in. I called my local urgent care who told me they couldn't help me - no one there could remove it for me. I was so desperate once I realized that the Mirena was the only aspect of my life that had changed during the time I decided I wanted to set fire to myself that I wanted it out immediately. I researched self-removal online and was substantially reassured by the results of that research that it was possible so I decided to remove it myself. I pulled gently, slowly and it came out without incident. I had no spotting afterward and only minor cramping. I woke up the morning after already feeling more optimistic. A string of things went wrong that morning and I never once thought of hanging myself from the attic rafters. There was a gigantic and immediate improvement. That was two days ago. I am still having horrible migraines and my breasts are still extremely sore, but I have not had a single suicidal impulse since. I even think my sex drive, which had disappeared completely is starting to return. Last weekend I told my husband that I wanted a divorce and needed to move out of the house immediately. This weekend we are going out on a date and I can't stop trying to cuddle with him:) I'm almost certain that making the decision to remove the Mirena saved my marriage and quite likely, my life. Bottom line, EVERY woman will react differently to Mirena and EVIDENTLY each time you have Mirena placed the side effects can vary - greatly. I hope this helps someone.

I am writing this because my girlfriend is currently in a rehab facility for Alcoholism and depression. Tonight we came to the realization that the severe depression, suicidal thoughts, and alcoholism all coincided with her starting the NR. She has suffered from depression in the past but since starting the NR it has become so severe that she had to be admitted to rehab facility. Reading this makes me realize that she is not the only one suffering from such adverse side effects. I believe that if anyone is suffering from depression or anxiety that it would probably be a good idea not to use a medication that messes with your hormones.

This is the biggest relief. I am sure you can all relate finding this website. I started using the nuvaring back in February and the side effects started soon after, I just haven't tied it to the birth control until now. The first month I started using it I was planning to move from my home in boise to Orlando Florida to live with my boyfriend.. which is very stressful so needless to say my high anxiety stress irritability and anger all seemed to be pointing to the stress of moving from my home although it is what i wanted it was still scary. I have been here in Florida for 3 months now and still experience the same things adding one to the mix as living with your boyfriend should spark an instant sex drive when you haven't been living in the same city for a year. NOPE no sex drive at all. Maybe once in a blue moon i get in the mood but i literally have to talk myself into it which is pathetic. There are times when i am laying next to him and i have to tell myself if he wants i should go along with it. but though of sex just drives me away. Also the depression is unbearable I am a very happy goofy person and it is a struggle to keep my temper in check or to try and work up motivation to leave bed. I am constantly tired and have no drive to accomplish anything anymore which is out of my character.
Headaches I have always had and migraines i have had before the nuvaring about once a week now i have migraines at least 3 times a week and a headache every day in between. My breasts have been extremely sore so much that i thought maybe i was pregnant in combination with my extreme mood swings. I have thick hair and i shed a lot never thought that it may be due to the birth control. I am getting somewhat angry that this is the way we all have to find out. It is frustrating to feel like a crazy person and wonder what happened to the person i use to be. I have not experience any weight gain fortunately, but since have no motivation i am not in the shape i once was because i have no desire to go to the gym.
The itching sensation i didn't realize as a symptom before reading others stories. Now it is so clear how aggravating. One month my cramps were so bad and a couple of months in a row i felt so nauseous that i would get sick. One time i was driving to a friends house when all of the sudden i knew i was going to be sick and ended up vomiting all over myself... so embarrassing and i couldn't figure out what happened. Tomorrow morning im calling my doctor to see what we can do. This is my last day with the Nuvaring Thank god for this site and thanks to you all sharing your stories it brought me peace of mind knowing ill be myself again soon.

I just turned 18 years old and was prescribed Doxycycline Hyclate 100mg, BenzaClin (Benzoyl peroxide), and Differin 0.3%. I've been on benzaclin and differin for about 3 years now. About 2 months ago I was prescribed doxycycline for my acne. I specifically told my dermatologist that I wanted a higher dosage of acne medication since the minocycline 5mg wasn't strong enough for me; I had taken it 2 years prior to my visit. But when I would take doxycycline I'd feel a litte bit of nausea coming my way so I decided to drink some water with it. Shortly after I'd get something to eat. I'd feel better soon after. I've been on this medication for almost a month now and I'm not feeling any adverse side effects. My acne has somewhat cleared up but then i breakout again, around the same area. I'm hoping my acne will clear by the time I go for my check up in feb but if it doesn't, i want to be prescribed accutane instead. Also, stop the medication if you're having horrible side effects, obviously there's something wrong. It could also be an allergic reaction, I'm just fine but then again, I'm not allergic to anything and I also avoid a lot of sun exposure.

Hi,
Back in May of 2008 my it was alleged by doctors that my mother needed to have her gallbladder removed. During the surgery, she was given Diprivan 200MG AMP, and Fentanyl 5ML vial. Since the surgery, she is yet to recover. After seeing many local doctors and surgeons, we decided to go to UNC Chapel Hill, where the doctors there cannot even tell her what is wrong. She has since (the surgery) also developed C-diff. She has had her medical records released an I'm trying to take this into my own hands as I'm tired of seeing her literally get sicker and sicker. Here's my question: Is it possible for these side effects to last over this long period of time, from just having a 5 ML vial of Fentanyl? The reason I ask is because every above listed symptom that people have had after using the medication, is what she goes through on a daily basis. Here is a small list of her daily symptoms: flue like symptoms, hot flashes, constant fatigue, sometimes diarrhea, sometimes vomiting, slurring of some words, disfunction in her language ability -- sometimes she cannot read a sentence clear on her first attempt. EXTREME short term memory loss, physical instability, as well as weakness in her body. I've researched side effects of this medication and those are all listed, and I've seen more lists above. Is it possible for her to be having long-term adverse side effects from this medication? Is it possible for her C-diff to be related to the medication? If anyone could help with anything I could greatly appreciate it. While this is risky, I'm going to put my personal email because I just need immediate help and advice from anyone, and I check my email ample amounts of time throughout the day. So, please email me if you have any suggestions. ******

Hi, I have been on Yasmin for just three days and in that time I have had severe diarrhea, nausea, and vomiting. At first I just thought I had a bug or food poisoning but no-one else in my family has come down with the same and even though I have not eaten in 48 hours it seems to be getting worse.

I just don't know whether to stop taking the pill right away or whether to finish the packet. I don't want to have a dreadful 2 week period that some people are describing but I can't go on like this ... I am literally bedridden. Has anyone else had a similar experience or if anyone could offer any advise I would be grateful.

I am so relieved to see these posts. My husband started Wellbutrin 2 weeks ago. We are at the beach and yesterday he started experiencing itchiness followed by rash and welts that have spread and are huge now. He has them on his legs, under arms, around waist and on feet. This morning his right eye became extremely swollen and now his lips are HUGE.. At first we though an allergic reaction to seaweed until it started getting worse. I googled benadryl and wellbutrin to see if they could be taken together and found this sight. He has also been complaining the last week with chest pains and I see some people also experienced that. Thank you all for sharing for now I can see what is causing it and we are stopping Wellbutrin now.

I want to ask a question. My mom takes Lipitor and just started Vit b . is there side effects to be expected? She just started a new bottle of Lipitor and is exper. dizziness. is this a side effect of one or the other?

I already posted on here about all the negative/adverse side effects of the Mirena that I have experienced and that were completely dismissed by my doctors. I would just like to suggest going to the FDA website to report your adverse side effects. The more people that do this, the more recognized these negative experiences will become. Hopefully, at some point, medical providers will finally acknowledge that some women may not respond well to the Mirena.

I have been taking this pill for about 2 years now and have had many of the symptoms you are all describing. If you miss it for one day, you start to bleed. If you are on any other meds (I am on thyroid medication), you may have adverse side effects. After reading all of these posts and experiencing these issues for so long (My doctor told me that it was because I wasn't taking the pill at the same time every day), I am finally going to try something else. I think it's b.s. that you start bleeding after missing one pill or are off an hour in taking it. Any suggestions for other birth control that others are happy with?

TO ALL

MY SON LOGAN IS SIX NOW AND JUST FINISHED KINDERGARTEN TODAY.
WHEN HE STARTED KINDERGARTEN HE WAS ON SINGULAIR FOR 4 YEARS. HE HAD ALL TH ADVERSE SIDE EFFECTS. TUMMY ACHES, CONSTIPATED, DIARRHEA, LEG CRAMPS TO POINT OF NOT WANTING TO WALK, BEHAVIOR PROBLEMS, HATED EVERYONE, NIGHTMARES, SEES GHOSTS, CRIED OFTEN.

ANYTHING SOUND FAMILIAR. HIS MOTHER THOUGHT HE HAD ADHD OR ASPERGERS AND PEDIATRICIAN AGREED WITH HER.

SOMEBODY THAT I THINK IS SPECIAL FOR ONE WAY OR ANOTHER KICKED ME IN THE RIGHT DIRECTION TO INVESTIGATE SINGULAIR IN EVERY ASPECT.

FIRST WEEK OF GARTEN I HAD TO HAVE A CONFERENCE WITH COUNSELOR AND THREE TEACHERS AND HIS MOTHER.
I LET THEM TALK AND EXPLAIN THEIR THOUGHTS ABOUT LOGANS PROBLEMS. I THEN DROPPED A BIG PACKET OF PAPERS ON TABLE ABOUT SINGULAIR AND ZYRTEC. THEY WERE VERY VERY SURPRISED THAT I PRODUCED THIS INFO.

THAT DAY HIS MOTHER AGREED TO TAKE HIM OFF SINGULAIR. IT TOOK ABOUT 6 MONTHS FOR LOGANS ADVERSE SIDE EFFECTS TO SUBSIDE. HE NOW ONLY TAKES ZYRTEC AND IS GROWING SO FAST.

SO PROUD OF THE LITTLE TURD!!!!!!!!!!!!!!!!!!!

IM NO DOC BUT HOW DID KIDS AND ADULTS SURVIVE ALLERGIES IN THE OLD DAYS?

GIVE IT TIME LET THEIR IMMUNE SYSTEMS CATCH UP. KIDS DO GET SICK. DO YOUR KIDS A FAVOR AND INVESTIGATE THE DRUGS DOCTORS PRESCRIBE THEM. SOME HELP BUT SOME HURT!!!!!!!!!!!!!!

TAKE CARE AND GOD BLESS ALL!!

I was first prescribed Neurontin in November of 2008 for cervical disc bulge touching my spinal cord causing severe nerve pain in my left extremities. I was prescribed narcotics and eventually prescribed Neurontin. The side effects from Neurontin, at that time, were seemingly intolerable, but as the narcotics were decreased several months later, I found the Neurontin was actually effective and did its purpose. The side effects from the Neurontin were not that great to outway the pain factor I had. I believe this drug does its job!!!!

OMG! I had Mirena put in Nov. 2007. Recently I had pain enough and spotting right after my period. I went in and during the exam my new ob said she could not feel or see it! I had a ultrasound which showed a cyst on my ovary that burst causing the pain but NO MIRENA! on May 4th. The OB said that I must have past it and she could not do anything until I started again. I started and contacted my previous OB (who put it in) and the nurse was stunned! She said they just don't fall out. I had an xray today and we found it......in my stomach lining! The OB isn't worried that about it but everyone I talk to wonders how it will keep from moving on around! The nurse said it would take major surgery now to remove the Mirena from my stomach. How does this go through the uterus lining? Are there holes in my uterus and stomach? How could this not be concerning to my previous OB? I have called the 888# on the back of the Mirena brochure and reported adverse side effects that the operator highly suggested to surgically remove the Mirena. I asked if they would pay for the removal but she gave no response. Of course with tough times we don't have the money for such a surgery but my husband and I are worried about further complications this may create. After reading many of these I know now where my mood swings and irritations come from-my poor husband, 8 yr old and 1 1/2 yr old!
DO NOT GET AN IUD IF YOU DO NOT NEED TOO. BEWARE!!!

OMG! Thought it was due to my age. Thought I was going crazy! Everyone of these issues I have.
Headaches, fatigue, fuzzy head, incredible appetite, quick weight gain. I also have lost a lot of hair and have hair damage (very dry and breaking off).
My doctor actually suggested this product to help with my PMDD. Did not help me just created another set of issues. I do not need birth control I need the hormones but not that bad.

Has anyone else had problems with their hair?

I haven't really had any adverse side effects in particular from my mirena. The insertion of my Mirena was a nightmare though. I have had three children, all of them via c-section and my doctor neglected to inform me about the insertion process in general. That it would be much easier for her to insert it had I had my children vaginally.
I went to my doctor and they got ready to insert my mirena and realized that the tool that they used to open my cervix and insert it was too short since my cervix is apparently very far up. So they had to go fetch a longer set of scary looking tongs. They then proceeded with the insertion which hurt so badly that I started crying. My poor husband had to hold me down on the table it hurt so bad. Then, after all was said and done she decided to ask me if I had ever dilated and I told her only with my first daughter and only to 7 1/2 cm. She then decided to tell me that was why the insertion was so difficult. That was, by far, the worst pain I have ever been in I believe.
After the insertion I had some pretty bad cramps and bled for a day or two but I haven't experienced anything other than that. Well, I do occasionally have a kind of sharp pain in my abdomen. I suppose it might be my uterus but hopefully it's all okay because I SERIOUSLY DREAD getting this mirena out. They will have to put me to sleep or give me a bunch of pills in order to get it out. I don't want to go through that pain again

I have been getting Kenalog injections on and off since I was a teenager. I am now 38 years old. I get these injections about once a year and depending on how bad my allergies get, sometimes twice a year. It is the ONLY MEDICATION that I have ever been able to take that has completely relieved my allergy symptoms. I to have got the "dents" into my skin at the injection sites, which over time have resolved on their own. My hips ache as well but fortunately only just sometimes. Exercise relieves the pain. I am a nurse and know full well the "adverse" side effects from this medication and am reminded by my physician every time I go for the injection. The misery of dealing with my seasonal allergies when nothing either prescription or over the counter helps makes me incredibly grateful for this medication. Everyone will react differently to every medication. People need to realize that it will not work for everyone and there are serious side effects. That is when YOU need to decide if the risks are worth the potential benefits. For me they are, every year I dread spring and summer and will dread it even more if the FDA pulls this drug.

It seems most people on here are blaming their "side effects" on the medicine. Could you quite possibly have health issues anyway? what about those people that don't take Singulair and have the exact same symptoms? Is it because they are THINKING about it?
It's one thing to be informed about medication. It's another to go overboard.

Researchers have been doing studies for many years regarding trying to determine the role of genetic factors in patients response to Singulair (Montelukast).

This study from Spain identified the following gene variations hypothesize to be related to leukotriene pathway response. Sixty one patients with asthma were studied. Three gene types were identified:

type 1. Thirty-two patients (52.5%) were homozygous for the five repeats allele;
type 2. 17 (27.9%) were heterozygous (4/5 repeats)
type 3. 12 (19.7%) were homozygous for 4/4 repeats.

The study showed that montelukast was effective for types 1 and 2 but not effective for type 3. Type 3 represented approximately 20% of the group study.

"After the montelukast treatment decrease number of asthma exacerbations, improvement of FEV(1) and decreased use of beta(2) agonists was observed in patients with 5/5 or 4/5 repeats. Conversely, the patients with 4/4 repeats genotype did not modify these data after treatment."

So it seems logical that if it can be identified that montelukast is not effective for certain gene type variations, then montelukast could cause adverse side effects in certain gene type variations.

It is interesting that 20% of this group does not respond positively to montelukast. That is the exact same number that even Merck says gets a headache from montelukast. Headache is the highest incidence of adverse side effects that has been reported. That comparison, however, is just a coincidence because it has not been studied and proven. Maybe.

Where are the studies that pertain to gene type variations and adverse side effects? You would think that somebody could do them.

Respir Med. 2008 Jun;102(6):857-61. Epub 2008 Mar 12. Links
ALOX5 promoter genotype and response to montelukast in moderate persistent asthma.Telleria JJ, Blanco-Quiros A, Varillas D, Armentia A, Fernandez-Carvajal I, Jesus Alonso M, Diez I.
Institute of Biology and Molecular Genetics (IBGM/CSIC), University of Valladolid, Valladolid, Spain. ******

BACKGROUND: It was hypothesized that asthmatic patients with mutant alleles in the leukotriene pathway should not respond to leukotriene receptor antagonists and the concept of a tailored treatment is increasingly supported. METHODS: Sixty-one patients (mean age 24.9 years, range 14-52) with moderate persistent asthma were clinical and immunological assess prior and after a 6-month treatment with montelukast. Tandem repeat polymorphisms were genotyped in the promoter (-147 to -176) of 5-lipoxygenase gene (ALOX5). RESULTS: Thirty-two patients (52.5%) were homozygous for the five repeats allele; 17 (27.9%) were heterozygous (4/5 repeats) and 12 (19.7%) were homozygous for 4/4 repeats. After the montelukast treatment decrease number of asthma exacerbations, improvement of FEV(1) and decreased use of beta(2) agonists was observed in patients with 5/5 or 4/5 repeats. Conversely, the patients with 4/4 repeats genotype did not modify these data after treatment. CONCLUSIONS: It was confirmed that ALOX5 promoter polymorphisms have a clear influence in montelukast response in atopic moderate persistent asthma patients. The genetic study could identify those patients most likely to respond to montelukast.

PMID: 18339529

16 days ago on Jan 17, 2009 by chris555, #16131
Sorry to disappoint you, but I have no vested interest in Merck or any other pharmaceutical company for that matter. What I have a vested interest in is providing some balance to those parents who come to this blog site and are scared to death. That is what happened to a very good friend of mine. After reading the posts here, she was so panicked she took her 12 year old off Singulair. A kid who had no problems on it by the way. A few days later my friends kid was rushed to the ER and almost died from an asthma attack. That is what I have a problem with. People here telling others the side effects will creep up, that kids should stop their medication right away, etc.

Reply 8 minutes ago on Feb 03, 2009 by concernedcitizen, #16701
To chris555:

Merck warns on it's Singulair website that Singulair is not an effective replacement for fast acting inhalers in the event of sudden symptoms. Originally when Singulair was developed it's purpose was to prevent damage and inflammation that is caused by excessive number of eosinophils in respiratory tissue. There is no evidence at all that Singulair is effective as the only treatment for asthma to prevent or treat acute asthma attacks. And, Merck makes this very clear in the warning notice.

The efficacy and safety of Singulair has a genetic component. That means that it is entirely possible that some people are not compatible with the way in which Singulair works. Adverse side effects are very possibly the result of compatibility problems.

Sadly, Merck has succumbed to the disease of "corporate greed." Meaning that they care more about profitability and the shareholders than they do about the patients. For this callousness, some day this corporation will suffer the punishment. Merck has always known that the cysLT1 receptor is a gene with more than several variations. If they told doctors to watch out for side effects due to genetic variations, then they wouldn't be able to sell this drug like it's harmless - cherry chewable - candy. The adverse side effects are real. Patients started reporting them immediately when the drug was released. Singulair is dangerous to people with gene variations and it causes unnatural biochemical events to take place.

IMPORTANT SAFETY INFORMATION
SINGULAIR will NOT replace fast-acting inhalers for sudden symptoms. You should still have rescue medication available and continue to take your other asthma medications unless your doctor tells you to stop.

To get the real information in regards to what level of research that is going into this investigation is.go to the Institute for Safe medicine practices click on Quarter watch.
To people like chris555, I believe you are engaging people for sport and say very hurtful things,your day will come and it may just be in the unemployment line.I can only imagine that you must work for Merck or you would not feel so threatened by the good that has come from Parents advocating for their childrens safety.I want you to know, that all who knew our family and our child understand what took place and our reasons for trying to get the proper information where it should have been," on the label". When our child died no one knew about all the added side effects from post marketing reports,which is "a reliable way to track a drugs adverse events".Maybe you should do more research on the legitimate information of causal relationship. Don't be so afraid of a possible drop in revenue for the drug company that I believe you might be an employee of.K. M.