Allergen symptoms and conditions

Hi there... I came off of Yasmin just 2 weeks ago and thought I should share with you my story since yours is a skin issue. I took Yasmin for 3 years. This past year I would wake up some bumps on my lip.. then on my hands.. then (this is over a period of months) I would wake up and have a slightly swollen lip... this was over the last year or so. I would also get a feeling in my throat, like something was in it and swallowing felt funny.
WELL, 2 weeks ago, I took my bc like I always do, right before I go to bed and my lip starts to tingle and itch.. and in the morning my face was swollen 3x the normal size on on side, mostly at the lips... I couldn't really talk.. it was like those awful photos on google. It was angioedema and can kill you by swelling of the throat. I had also for about a year- an ear issue.. it would sound like I was talking under water and felt like swimmer's ear- related to the swelling I found out later. Turns out I'm allergic. I developed this allergy over the period of time I was exposed.

I just want to say to anyone out there that has FACIAL/LIP SWELLING, or swelling of the hands... GO TO THE ER. It can kill you. I got lucky.. my swelling started slow and after about a year if was full blown. It is not something to mess around with!I was prescribed an epi pen. I developed an allergy to a preservative in it and I'm not an allergen sensitive person. That was just the parms/doctor guess I might add.

The first year I took Yasmin I had numb and tingling toes. and the whole tie I've had on and off leg pain.. no sex drive, that's the truth..definite bloating issues about 6 lbs weight gain, sometimes more without change in diet. I haven't noticed any hair loss thankfully. Migraines. Lots of nausea in the morning, every morning like morning sickness. Car sick even when driving.. not normal! I used to work on an airplane and I never got motion sickness.

I'm now on day 4 of Mirena IUD and I'm having having severe diarrhea and trouble sleeping.. I really, really don't want to get pregnant. Our next step is a vasectomy for the hubby. I'm 25 and I weigh 140 5'10 if that helps. I wasn't an 'at risk' like the pamphlet said.

I'm so glad to find this forum. I've been on Yasmin for 7 months since March 2009. My gyne recommended me to take it because of my acne problem, heavy period and cramps. Ever since I started taking it, I was happy about it. My face is cleared of acne and my period only lasts for 3 days and very light without pain. I was a happy camper until the 4th month into taking Yasmin. I started to have patches of rash on my right temple, then a week later on the left temple and upper lip too. At first I thought it was due to my new face toner. So I stopped using it. I didn't think it would be the pill as any allergic reaction usually would should up 1-2 months after taking it. The rash got worst after 2 weeks, it started around my waist, more like hives this time. I can't stop itching my skin even in my sleep. It was unbearable. The hives comes and goes. And it spreads bigger and bigger to behind my neck and back. I drives my NUTS and my skin is very dry. I saw my family doc, and he thought it was eczema/fungus. He gave me some steroid cream to apply. It helped but didn't make the hives go away. I kept looking for the cause of the hives, but have no clues. After I read many people who posted in this forum also suffered the same problem, I can conclude that Yasmin is the reason. I'm stopping the pill today!!!! Hopefully, the hives will go away soon.

My 7 year old female Siberian Husky, Niceah is suffering with her second serious flare-up of IBD. She was taking 20 mgs. of prednisone every 12 hours for several days. We are now down to 12 mgs. daily and working towards 12mgs. every other day. She is lethargic and her body and belly have swollen frightfully to the point where it is difficult for her to lie down without grunting and sighing. She pants heavily. She drinks and eats constantly. Her nose is dry. Her tummy grumbles all day and night. I have been boiling chicken breast and mixing it with sweet potato and Enzymes & Probiotics. I am currently working with a holistic advisor concerning Niceah's diet once she has weened off the prednisone. The side effects of this drug are frightening and I am so worried that something more permanent and damaging will occur. Has anybody experienced this?? If so, I would appreciate any advise. Robin. copher370@aol.com

could anyone tell me if claritin is the same as singulair or what i could give my child that would help with the allergies/stuffy nose she was on singulair and was taken off

I just discovered a new, drug-free way to help treat children's allergies. It's called Little Allergies Allergen Block.

It works by helping to block airborne allergens before they enter the nose.

I am going to try it with my son and will post if it is a success. If anyone else tries it, or has tried it, please email me and let me know if it worked for your child.

My 6 y/o daughter has been taking Singular for approx. 2 years. She began to have regular stomach pains shortly there after. She was sent to Children's hospital where they put her on a laxitive which made things worse. Then we began testing for food allergies only to find out that she tested positive for a 3 page list of foods. We eliminated those food and had her tested again. She was subsequently allergic to the foods we eliminated. She was recently down to rice, a few meats and some vegetables. Guess what, she is now allergic to those foods.

All this time she has been complaining of severe leg pain, eye pain, throat pain, numbness and tingling in her hands a feet, all of which come an go. I have reported this to all the doctors and specialists we have seen. She had undergone countless blood tests to rule out autoimmune disorders and all come up negative.

She began to develop severe anxiety and just had the blues most of the time. She would be crying and saying off the wall things like, "I don't think my fish is happy". She couldn't stand to be away from me and would stress out about even weather or not she would sit by me at a restaurant. I mentioned this to all of the doctors. They said to not make too much of it. One suggested she see a psychologist. NOT ONE DOCTOR EVER LOOKED AT THE SINGULAR.

Finally about 4 weeks ago my neighbor who is a scientist at a pharmaceutical company called me and told me about the "black box" warning that had just come out on Singular. I took both of my children off of it immediately. My daughter went through about a 10 day period where her anxiety got worse and then it was just gone. We are adding foods back into her diet and at this point she has not had any severe allergic reactions.

The last 2 years have been a complete nightmare for her and for us. I am a medical professional and I have had doctors treat me like a hypocondriac, hypersensitive, attention seeking mother. I feel so justified and saddened by the recent findings all at the same time. Most of all I am so grateful that we figured this out before things go even worse.

Please let me know if anyone else is suffering food related reactions as a side effect.

My four old son has been on singulair for about two weeks. The change from wheezing/coughing attacks at night and terrible allergies during the day has been amazing. They are almost non-existent to this point a great plus. However, a i stress however his behavior and speech has been VERY INAPPROPRIATE and quite frankly it concerns me. He now states "im a bad boy" and "i dont listen" and his mornings are very testy to say the least. Granted these sound like normal 4 yr. old sayings that he would pick up from other children on the playground but how do you explain them happening almost simultaneously with his taking singulair. I find it very hard to believe that it is a coincidence and that these are normal things for a 4 yr old to say/do when all other things have remained the same. My advice is to diligently watch your child for these warning signs and find other remedies if you have reservations. Im not promoting natural cures but i am leaning toward a diet change for the whole family and consulting my doctor for food allergen testing. I hope this helps. Be Well.

These posts about contacting a bad viral infection while the immune system is suppressed by Singulair are particularly worrisome. This was from 2007 so it has nothing to do with the FDA investigation. Epstein Barr causes some really bad illnesses including lymphoma.

The scary part is that children are the most susceptible to viruses. They need to develop immunity at a young age that will build up over time to levels that will protect them for the rest of their lives. Why are we giving children a drug that will suppress the leukotrienes? Why do we think that it is okay to take away one of the bodies defense mechanisms? Wouldn't it be logical that a drug that suppresses the immune system is a last resort option not handed out like lollipops?

www.iddb.org/drugs/singulair/ - 243k
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Anonymous Immune System Dysfunction September 13th, 2007

Do users of Singulair and Advair understand how these products work? In order to understand how they work, you must first know what happens in the body during an allergic attack.

Allergic response is a function of the body's immune system. When an allergen enters the body through the nose or the lungs (e.g., a bit of pollen or cat dander), it is recognized by the body as a foreign substance, and the immune system then produces histamines to fight the intruder. Singulair and Advair work by disabling the body's immune system, so that there is no allergic response.

I too thought these drugs were wonderful. I was on both Singulair and Advair to combat asthma from my new husband's cat. I took high strengths of these drugs for approximately three years.

During the time I was on these drugs, some disease entity, most likely a virus (e.g., Epstein-Barr, Herpes Simplex I, HTLV I). I have been sick with a fever for the last four and a half years. My immune system seems to have been permanently impaired, and every organ in my body is now compromised. I have a fever, night sweats, liver and spleen enlargement, digestive problems, skin infections, hypertension, rapid-onset insulin-dependent diabetes and other endocrino;ogical problems, blood cell abnormalities, and neurological problems (e.g., tremors, myoclonic seizures, muscle cramps and weakness, vertigo, incoordination).

I am about to undergo a spinal tap and other tests, looking for the causative entity. Whatever it is entered my nervous system when I had an epidural anesthetic while on these immune system depressants. I have not been the same since. I have been too sick to work. This has ruined my life.

As we have all learned from recent reports of heart damage from Vioxx, the FDA no longer has the money to fully test new drugs entering the market. The "clinical trials" are a drug's entry into the population. If it kills or sickens too many people, they withdraw it. However, the drug companies define "too many people" as a number that could potentially ruin profits through lawsuits.

MORAL OF THE STORY: Don't rely on the government to protect you. Before putting any drug into your body, do the research into how it works. Read comments from other users. I wish I had done that.

My 13 yr old daughter was put on Singulair along with Asmanex and Clarinex for her asthma about 6 weeks ago. Everything seemed to be going very well at first and her symptoms were starting to get controlled. I started noticing after about 3 to 4 weeks that her temper and attitude were getting much worse. Anyone with children this age knows what I mean but this was like a 180 degree turn for her. Her actions were becoming totally out of character. Before I knew it she would cry and get highly upset over the least little thing. Week 5 came around and things totally bottomed out. She came home from school and WAS NOT HERSELF. Made comments about how she hated her life and it was not worth living. Later that evening we had a big argument because I was telling her nothing was worth saying that. She went totally out of control and I had to physically restrain her to calm her down. It appeared everything was better so she went to her room. I went down to check on her and she calmly told me that she had taken advil and tylenol pm and things would be better for her forever now. We went to the ER where they made us wait for at least an hour, then finally took her back. She had to drink two cups of charcoal and was poked and prodded repeatedly. They did a catheter to get a urine sample. She was very cooperative but also was in a complete daze so who knows. The poor child couldn't even lift her head up when she started the vomiting to get rid of the drugs. It was very upsetting and sad. Her heart rate and blood pressure went very low and I really thought in the back of my mind that this was it. Finally, after several hours she started coming out of it and they sent us home. The next evening when she was starting to really come around she proceeded to tell me how she had been seeing a man walking around in her bedroom at night and she was afraid to go down there. Breaking down and crying telling me about all of the horrible nightmares she had been having recently and didn't know why. I thought what am I dealing with here? This just isn't her. Three days ago I heard about singulair in the news and looked it up on the internet. OH MY GOD THIS SOUNDED LIKE US!!!!! I immediately had her stop taking it and the next day phoned her asthma specialist who agreed she should stop now. We are going to watch her for two weeks and see if any symptoms return and then decide if she needs something else or will be fine on just the Asmanex. As a side note, she also mentioned being unable to concentrate in school (unable to do even the simplest math problems) and that her brain felt confused or like something was missing. She said this had been bothering her for several weeks. I know it was this drug. They really need to take this off the market NOW and stop flirting with disaster. The only reason I posted this was to let others know they are not alone.

Effective after two weeks for some people - not effective for others. Side effects for some people - others do not report side effects. So why does Merck have to grow their market before they have any idea what's going on?

This isn't a big group of people in the study but it makes sense from what we are reading here. These researchers did examine the mast cells. We need to know about mast cells (while suppressed by montelukast) on a longer term basis.

J Asthma. 2008 Apr;45(3):243-50. Links
The efficacy of montelukast and airway mast cell profiles in patients with cough variant asthma.Kawai S, Baba K, Matsubara A, Shiono H, Okada T, Yamaguchi E.
Division of Respiratory Medicine and Allergology, Department of Internal Medicine, Aichi Medical University School of Medicine, Aichi, Japan.

Background. Cough variant asthma (CVA) is characterized by chronic cough without apparent wheezing; its pathophysiology is considered to be similar to that of classic asthma. Objective. The clinical effects of montelukast, a cysteinyl-leukotriene receptor antagonist, on cough variant asthma were assessed, and the activation profile of airway mast cells was examined. Methods. Montelukast (10 mg/day) was given orally to 36 CVA patients (25 women and 11 men; median age, 37.5 years). Before treatment, the patients' bronchial mucosa underwent a biopsy with a fiberoptic bronchoscope. The biopsy specimens were double stained with anti-CD63 antibody and anti-human tryptase antibody. Results. After 2 weeks of montelukast treatment, cough symptoms improved in 22 patients (the effective group) but did not improve in 14 patients (the ineffective group); in the ineffective group, the symptoms disappeared 2 weeks after they were switched to fluticasone propionate (400 mug/day) inhalation therapy. In the effective group, the time interval from the onset of symptoms to the initiation of treatment was significantly shorter than in the ineffective group. The bronchial mucosa biopsy specimens showed that the proportion of CD63-positive cells in tryptase-positive mast cells was significantly higher in the effective group than in the ineffective group; although the total numbers of mast cells were not different between the two groups. Conclusion. There is a subgroup of CVA patients in whom leukotrienes are closely involved in the pathogenesis of their chronic cough; activation of airway mast cells may be an essential feature in these patients.

PMID: 18415834

Firstly, there is hope! I have been off the evil Advair for 8 months now, I have my Ventolin at the ready but typically I use it one or twice a week...and when I do I hold it at arms length away and only inhale a tiny amount.

Okay a little rewind to the start of my recent problems. I went to an allergy doc since my asthma seemed to be getting worse, he did the test where they scratch your back with 70 or so allergens, from the reactions he determined what some of my trigger are. Turned out to be house dust mites, mold, grasses, cats, horses, shrimp etc. Then the idiot put me on Advair rather than dealing with the real issues.

After 2 years on this evil substance, my chest was so tight when I didn't take it, and generally my breathing was the worst it had been my whole life. I felt like there was something in my lungs that I just couldn't cough up...this gradually did subside. Long steamy showers helped me a little here.

So this is what I did.
Bought a copy of Reversing Asthma by Richard Firshein, a must read, he was a chronic asthmatic and reversed his own condition, you must buy this book.

Armed with my known allergies, I cleaned up the house, bought the pillow covers that keep the dust mites out. I sprayed all the carpets and duvets with an anti-allergen spray. And of course avoided my other known triggers.

I bought a Microlife digital peak flow meter to map my progress.

On Richard Firshein's advice I take a whole host of daily supplements, cod liver oil, vitamin C, magnesium, beta carotene and so on.

I exercise 3+ times a week and I bought a PowerLung Lung Trainer to build up my breathing muscles (I haven't been using this a whole lot so far though).

I'm still working on finding my triggers, so I still have days that aren't as good. I think something I occasionally eat or drink is bothering me. Oh and I found being dehydrated seems to cause my breathing to go downhill.

All the best to you all.

I have been on mirena now for 10 months. I was on the depo for 10 years prior. I loved my depo adn only went off of it after Kaiser said I could not do it any longer. I was told that mirena was a god send and a lot like my depo. I can say that the combination of depo and mirena I have not had any period at all. but that is where the happiness ends. I have experienced moths of breast pain. it hurt to touch them let alone put anything on them. after about 6 months and numerous trips to the vet it disappeared. then I got a small rash on my neck and by my arms. went to dermatology and since then I have been there, or to my primary or an allergist every week since then. the rough severley itchy skin is constant. remarkably every 29 - 32 days it fades for 2 days or so and just when I am sure it is going away wham back it comes and each time it is getting worse and worse. having never had any skin problems before I believed the doctors tha tit was folliculitus, then they said dermatitus, then they said uticaria and then hives or the last straw i was causing it that it was in my head. i just got a new allergist and while she doesn't knwo if it is my mirena she can tell me I have histamine levels that are off the chart. my husband is allergic to a lot so we already use free & clear everything and my housse is spotless but I am still being told it is soemthing I am doing to myself. I have also been reevaluating my things and I relaize I have been experiencing a lot of numbness and joint pain. so much so that my primary sent me to a rhuematlogist and he ran every test for lupus, and many other diseaeses adn even cancer. I was going crazy. Iwas beginning to think maybe I was mental. I have since been researching mirena and I am finding it so much more than what the pamphlet says. I finally got the nerve to call my ob, adn she ahs since been researching things with me and we know for sure that no matter what next week I get my mirena removed. I am just feeling so alone and depressed. I am 33 years old and instead of enjoying my new marriage I am contemplating a divorce becasue I do not want him to be stuck with soemone who might be crazy. seeking support and anyone else who feels this way.

My husband developed hives from an unknown source. They have put him on prednisone now twice. His side effect is ANGER. He has been dizzy, hungry and angry. I am hoping they can identify his allergen soon to get him off this stuff. He was taking the tapering dose of 6 5mg pills per day tapering down to zero.