Anti inflammatory drugs symptoms and conditions

I am 53 years old and was advised to switch my BP med from Hyzaar
to lisinopril by the insurance company to save money. I took
20/25 Lisinopril/HCZT for about 6 months. My BP was so
low, I was getting lightheaded, so we reduced it to 10/12.5.
My BP stabilized at a reasonable level. Eventually, I started
to get chest pain around the sternum and ribs but it felt deep
inside. Also, I had wandering upper back pains -
stabbing pains - that would move around, but most often
would be felt in the middle of the upper back. I also started
to get occasional bloating where my abdomen would swell and
even be very rigid to the touch. Antacids had no effect. It
would eventually subside on it's own. I also developed painful
pericarditis 3 different times (swelling of the pericardium
sac around the heart and fluid buildup). The sensation is severe
pain with each heartbeat. I went to a clinic the first time and
received anti-inflammatory drugs and the second time I had to go
to the ER. The 3rd time, I self medicated with leftover drugs from
the previous episodes. I thought I was a dead man living on
borrowed time. I finally started doing research and found this site.
I stopped lisiniprol on a Friday and all symptoms of the chest pain
and back pain subsided within one day. In addition, I haven't had
any recurrence of pericarditis or bloating. Needless to say, the
associated anxiety of impending death is gone as well. I am now back
on Hyzaar and feel like a new person.

EVERYONE PLEASE READ!!!! GARDASIL HAS DESTROYED MY LIFE! I am 24 years old and a year and a half ago I was graduating college and planning to be a professional dancer and go to law school...I was perfectly healthy and energetic! In February of 2007 I received my first Gardasil shot. After a few days I started to feel as though I had a Urinary Tract Infection and was also feeling more tired than usual. The doctor gave me an antibiotic and sent me on my way.

In May of 2007 I received my second Gardasil shot and yet again, a few days later I started to feel like I was getting another Urinary Tract Infection. I went to the doctor numerous times between the second and third shot...all for bladder and urinary tract pain. For months I was on different antibiotics and they were not making the pain go away. After visiting a number of urologists, I found out that the urine cultures had all been coming back negative - showing no sign of an infection, so the antibiotics were pointless. All tests that I had run, both blood and urine came back normal. It is not standard procedure for a doctor to call you if your test results come back normal, but there was clearly something wrong, so I searched for a urologist who would believe me that I wasn't making up the pain I was in.

In August 2007, I had a cystoscopy done (they took a scope and went into the bladder to look in the bladder wall) and they concluded that I have an incurable bladder disease called Interstitial Cystitis. This is a condition where there becomes a defect in the bladder wall causing it not to have the protective mucus layer inside of it. The pictures of inside my bladder show red, raw skin, obviously showing the severity of my case of it.

There is no evidence as to what causes Interstitial Cystitis, and there is no proven successful way of treating it. The initial signs are exactly the same as a Urinary Tract Infection (painful bladder spasms, painful urination, body aches and back pain). The main difference is the fact that it is not an infection. There are thousands of people with Interstitial Cystitis who are misdiagnosed as having chronic Urinary Tract Infections.

I received my third Gardasil shot in October of 2007 and that is when EVERYTHING fell apart. The bladder pain became constant and there has not been one minute in a day since that shot I have not been in unbearable pain. This is when everything else in my body began to crash down as well. The other health problems and side effects from the Gardasil that I am having are constant sore throat, vicious migraines, vision changes, back pain, body aches, joint pain, sinus problems, vomiting, constipation, dizziness...I could keep going on forever!

I have tried all of the conventional treatment for Interstitial Cystitis and have gotten NO relief from the pain and other side effects. The doctors didn't know what to do, so they put me on OxyContin and a diet consisting of no acidic foods. That has now posed its own set of problems seeing as now my body is addicted to the narcotic, and I have gone from 5'6'' 125lbs to 100lbs over the course of a year due to the diet. I am extremely malnourished and have to take B12 vitamin shots once a week due to the severe anemia. I am 24 years old, and feel like I am 100. I can not live a normal life, I am going to lose my job from numerous absences, I lost my fiancé and am not able to have an intimate relationship anymore, I am extremely depressed, I have to have my family clean my apartment because I am too sick to do it, I can not do social activities because I am too tired and in pain. This vaccine has DESTROYED my life! I am desperately seeking out someone else who is having bladder problems due to the Gardasil so that I can contact an attorney. This needs to be OFF the market a soon as possible so that it does not run any other lives! Gardasil has caused some deaths, but in my mind, I'd rather die than live with the pain I am having. I did notice there are some posts regarding girls getting urinary tract infections... PLEASE PLEASE PLEASE have your urine cultured because there is a good chance it may be Interstitial Cystitis!

I am desperately looking for someone who is having some of these symptoms so that I can go to a lawyer and get something going before things like this happen: Numerous states are pushing to make it mandatory that girls receive the vaccine before they enter the 6th grade. We can not let this happen! We all need to stick together and somehow fight this and get out lives back!

Let me know if you are IN - and also what you thought about my post!

You can email me at ******

Bless All of You!

*~Amber~*

Many people have asked why I suggested that Omega-3 from fish oil MIGHT possibly help those retrying to recuperate from the adverse side effects of Singulair. It is my opinion, that it MIGHT help the body return to balance. And unless we OD on Omega-3 from dietary sources, (avoid tuna fish high in mercury), then it won't hurt.

Mechanisms and innovations

The science behind dietary omega-3 fatty acids
Marc E. Surette, PhD
Marc Surette is Professor and Canada Research Chair in Cellular Lipid Metabolism, Département de Chimie et Biochimie, Université de Moncton, Moncton, NB

Correspondence to: Dr. Marc Surette, Département

"When cells are activated by external stimuli, arachidonic acid is released from cell membranes and is transformed into powerful cellular mediators such as thromboxanes, prostaglandins and leukotrienes.10 These compounds possess a range of activities, including activation of leukocytes and platelets, regulation of gastric secretions, induction of bronchoconstriction and signaling of pain in nerve cells. The importance of these compounds in health and disease is evident by the range of pharmaceutical products that target their biosynthesis or action.11 Indeed, arachidonic acid metabolism is the target of nonsteroidal anti-inflammatory drugs (e.g., acetylsalicylic acid, ibuprofen), cyclooxygenase-2 (COX-2) inhibitors (e.g., rofecoxib, celecoxib12) and leukotriene antagonists (e.g., montelukast, zafirlukast).13 Dietary omega-3 fatty acids directly affect arachidonic acid metabolism because they displace arachidonic acid from membranes and compete with arachidonic acid for the enzymes that catalyze the biosynthesis of thromboxanes, prostaglandins and leukotrienes.8 Thus, the net effect of consuming foods enriched in omega-3 fatty acids is a diminished potential for cells like monocytes, neutrophils and eosinophils to synthesize these powerful arachidonic acid–derived mediators of inflammation and a diminished potential for platelets to produce the prothrombotic agent thromboxane A2." (Surette, 2008).

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I had a UTI and was given Cipro. I wake up shaking and having chest pain. My elbows hurt and my toes. I had diarrhea and stomach cramps as well as leg cramps. I am almost feeling like I have a panic disorder now, because I am so nervous about nothing. I wake up every night with either the palpitations in my heart. I thought I was having a mitral valve prolapse which I had almost twenty years ago. Now I have developed a spot in my eye like spider webs which now it has turned into a flash of light on the side of my right eye. I believe all this is from the Cipro. I was fine before it.

i'm glad i found this site. I had fluid in my ear drum. went to quick care and they gave me a prescription for levaquin 750mg. On the fourth day i woke up not able to close my hands. The pain and stiffness in my joints was severe. unable to hold on to anything. I also have pain in every joint in my body or it feels like it. What can i do to get this stuff out of my body? I ache all over. Need some feed back, please help if you have info on this.

I have been using Yasmin for almost 10 years. Recently I have began getting migraines (never had them before), nasty vaginal discharge and an embarrassing increase in facial hair. I can somewhat deal with the migraines, but the other two symptoms are extremely irritating.
I have been to my gyno for both. She told me that the discharge was "normal" with the use of Yasmin. I don't think snotty goo coming from your vagina for a straight week before your period is "normal". She assured me that all testing came back negative and it was just something I would have to deal with. As far as the facial hair goes...I can't leave the house without standing in front of a mirror and plucking my poor chin and neck for up to an hour each day. My gyno suggested that I get laser treatment, which would be grand if SHE were paying for it.
I don't know if I want to continue taking Yasmin or not. I have ovarian cysts and used to have severe periods lasting for a week and a half at a time, and Yasmin had helped with those problems.
Has anyone else had these problems...and what are you doing for them?

I am a 54 year old male and have been on Lipitor 10mg for nearly five years. I had a heart attack and since then have also been taking warfarin and also Atenolol 25mg and Candestartin 8mg. I have experiences some hair loss and some back pain. My short term memory is getting poor and I have dad days when I have felt generally unwell. Fairly recently I have had cramps and muscle pain in my legs and arms. Recently I began to have fluid collect on my knees and my knees joints have become stiff and painful. I have had the fluid drained from them and had various tests and x-rays. Everything is negative - there is no sign of infection or athritis. Liver and kidney functions are normal and gout has been ruled out. I am going to ask my doctor to check for muscle damage although he has already said that there is evidence of wasting and prescribed excercises for my legs. Is this the lipitor? He has give me some non-steroidal anti-inflammatory drugs to take in the short term but these interfere with my Warfarin and I cannot take them for long. I have looked up the side effects of the other drugs and they do not seem to be so severe as those of Lipitor. I live in the UK where self help in medicine is not so prevalent as it is in the States and my Doctor will, no doubt, be sceptical when I tell him about this site. What can I take to replace this drug?

Hair loss, which didn't occur to me until I read the postings - my hair is everywhere in the house but on my head! Muscle pain, weakness, and atrophy, itchy skin and eyes, joint pain (from muscle weakness??) is excruciating - after months on physical therapy was pronounced a failure and referred to a pain specialist and another surgeon. Could not raise my arms w/o terrible pain, hurt to drive my car. Nausea, dark urine, alternate constipation and diarrhea, dizziness.

I don't know whether to be excited or terrified after finding this site and reading the postings. At first reading, the only symptom I have NOT had while on Lipitor is the numbness and tingling in legs and feet. I've been concerned I have some terrible, undiagnosed and terminal disease.

Have had surgery on one shoulder and am awaiting surgery on the other, plus a re-do of a scoped knee which is now unbearably painful. Also have had multiple steroid injections at different sites, and am scheduled for another next week - this time in my lower back. Was put on Paxil for pain, but have weaned myself off that. Was diagnosed with spinal stenosis and fibromyalgia. Wouldn't take the meds for the fibromyalgia because of the side effect mentioned in the literature - HAIR LOSS! I was already losing my hair! Finally found a surgeon who told me to GET OFF THE LIPITOR!

Problem is, I had also been on Bextra at least four years, I think, for long term mild lower back pain, and knee pain, so am wondering if arthritis could have set in and been masked by the Bextra, which I came off of at the same surgeon's insistence. One week later it was taken off the market.

Am now off all anti-inflammatory drugs while awaiting my latest steroid injection, and yes, I do fear the side effects of THAT! My pain is back to the "rocking and swaying" stage, and I'm awake in the middle of the night researching Lipitor! Does it ever stop??

I have been allergic to NSAIDS for some time now, but my Dr prescribed Fiornal for headaches related to MS. I asked him a million times if this was ok to take because of my allergies and he said it would be fine. Well, I ended up in the emergency room with hives and swelling from my head to my toes!! If you cant take any NSAIDS (Non Steroidal Anti Inflammatory Drugs) stay away from this!!!!!!!!