Avandia symptoms and conditions

November, 2008 I started Januvia about 3 months ago while also taking metformin, glimeride. I previously took Actos but was gaining a lot of weight. Actos replaced the Avandia. The first few weeks on Avandia I seemed fine and the bs was okay. Gradually it increased along with severe painful spasms in my legs, trunk and daily in my neck. Eventually my hands began cramping. I also became severely constipated which is quite unusual for me. I then developed a series of upper respiratory infections. Since I was feeling awful I decided to research Januvia and its side effects. The manufacturer mentions the infections but not the others. As an experiment, I stopped taking the Januvia and within about 5 days, the painful leg/trunk spasms began to disappear. I'm contacting my doctor this week to find me a new drug....hopefully not insulin.

Wow. I started taking this when it first came out, a couple of years ago. I had DM w/uncontrollable BS's. BS's came down significantly. But now, a couple of years later, I've been experiencing a few night terrors, when first put on insulin and Januvia, I gained 20# and can't! get them off. I also have fibromyalgia,...so I didn't even think about the Januvia possibly accelerating, increasing, or changing what was going on with the fibro.

I get violently sick anything with Metformin, and swell up like an air balloon (gained 50! lbs. on the Avandia & Actos (MD screwed up and gave me both in maximum dose--I've had leg swelling ever since.) Anyone have any leg swelling/edema? They keep trying to put me on anti-depressants..I've had "real" depression before, and I don't have that kind of feeling, just exhausted, like I can't get going...fibro...or Januvia?

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I was taking Avandia since I found out I had Diabetes in 2000 . After all the bad news that was confirmed in 2007, I switched to Metformin then to Metformin and Januvia. The first three months after taking the Januvia, my blood pressure was high and the protein level in my urine increased. I was taking the Enalipril for at least 5 years for my kidneys . I never had high blood pressure. My doctor increased the Enalipril and three months later my blood pressure was still high and protein level more than doubled. I think there is a strong connection because it started right after I stated taking the Januvia. Any one else have this happen?

I have been taking Januvia for about 7 months now. Had to get off Avandia (another story). My levels are better and have lost weight. But, recently started getting a facial rash on both sides of the nose and have noticed some trouble swallowing at night when I lay down.

I have been on Lipitor for several years now, I am 54 year old female, had heart attack at 47 and at 49 triple by-pass, have diabetes and high blood pressure all under control. For the last 4 or 5 years have been having severe hip and leg pain, worse when laying down, doc finally sent me to specialist and he gave me cortisone shot which did not help. In the last few months my arms have been very painful, along with both my legs . My doc will say it is something else and wont test me, cause after all he wont even take me off Avandia which causes heart attack and has been all over the news lately. so he surely wont believe this.

I am a 66 year old male being treated for giant cell arteritis and have been on prednisone for one year and ten days. The disease and its treatment with prednisone has completely reordered my life. My doctor told me that I dodged the big bullet but there would be more. He was right. The 60 mg dose of prednisone I started with was both a life and eye saver. Three months later I was down to 40 mg and I was starting to sleep more than the two - four hours per night that allowed me to all kinds of things done which the increased adrenlin made possible.

Unfortunately, the prednisone made control of my blood sugar nearly impossible even with maximum dosages of metformin and avandia. I was soon forced to add injections of insulin to my daily regime. As I gradually reduced the amount of prednisone I gained some measure of control but was not able to start decreasing the amounts of insulin I was taking until I had dropped down below 20 mg. Now that I am down to 5mg I'm off the insulin and two weeks ago I took my last metformin tab.

Prednisone accelerated the growth of cataracts in both of my eyes. I was taking the prednizone with the hope it would drive the arteritis into remission and I would avoid going blind. And I was blinded anyway by the cataracts. Fortunately the cataract surgery I had in May and June better than restored my sight. I now only need glasses for reading. I was thrilled and could even see myself going back to work at least on a part time basis. No such luck.

After telling my doctor how great it was to be able to read again I mentioned that I thought I had a groin pull because I had been experiencing pain in my groin area and the top of my right thigh just above the knee. That got his attention and he said it might be related to the prednisone. He sent me for a MRI of both hips. The results were not good. I was diagnosed with avascular necrosis in both femur bones with some deterioration of the right femoral ball. A month later I had core decompression surgery of the right femur. The surgeon told me that we had caught it early and this surgery had a 50/50 chance of restimulating the venus blood path that fatty deposits caused by the prednisone had closed off causing the bone to die. Unfortunately, it now looks that it didn't work for me and I have additional micro fractures of the ball joint that weren't there when he operated. My left hip isn't far behind and I now have enough pain in both hips even with the anti inflamatory medicine I'm taking to make it difficult for me to walk to the mail box or negotiate stairs.

I hope that I'll be able to wean myself off the prednisone entirely, but for those folks that are putting up with all the most common side effects, getting down to and below 5 mg per day will seriously reduce if not eliminate the effect they have on you. That includes the fat face and turkey neck, and the thin skin that shows vividly every bump and bleeds profusly with the slightest abrasion that more often than not you can't recall the incident that caused it. The giant cell (also known as templar) arteritis disease I developed was devastating to me and really put me down for the count. I lost 30 of my obese pounds in the first two weeks of symptoms I had with this disease. Even though I was over weight, I was very active and got lots of exercise doing my own lawn work ( 1 acre lot) with a walk behind mower and lots of leaves to rake. Within two months after diagnosis I had managed to work my way up to a two mile walk everday. After 3 months I was walking between 15 and 20 miles every week. Now, as I said, I'm lucky to walk to the end of my driveway to get the mail.

Prednisone is not a miricle drug. It is a terrible medicine with terrible side effects that has been arround for a very long time. Unfortunately, it is the only medicine available to successfully treat a wide range of autoimmune diseases that have no cure and would be absolutely unbearable without it.

I've been taking 50 mg. daily (and conscientiously) for several years. I've been taking thyroid supplements (synthroid and similar) for 35+ years. For 15 years, I've been struggling with the gradual weight gain commonly associated with menopause and stopping smoking cigarettes (after 30 years of 1+ packs daily). HOWEVER, It was about six years ago that the problem became a 50 lb. overweight and BMI in the waist-over-35" serious problem. I was always strong, quick to build muscle, and enjoyed being active. Swam .5 mi daily or walked 3 miles (or both) frequently until about menopause time. But then: about four years ago, I started having some pretty serious trouble breathing associated with exertion. Body aches and pains that I've described as arthritic, may also be involved here! Hence decreasing exercise and real worry about engaging in exercise. I've also been taking Lipitor and Avandia.
Frankly, I'm feeling that all my meds except Synthroid can cause me to gain weight - the catch 22 being that my elevated blood pressure and early type-2 diabetes are also negatively affected by overweight!! Now what???? Dr. appt, very soon, folks!

i was diagnosed a year ago. started taking glucophage and avandia. major weight gain!!!. today,11/6/06 i stopped taking the avandia,as per my doc's approval. she said i should start to be able to lose some poundage!

WEIGHT GAIN, RINGING IN MY EARS, NUMBNESS OCCASIONALLY IN FINGERS, DIZZINESS, NAUSEA -- but I take 10 other meds.....these might be symptoms of one or more of them. PLEASE LET ME KNOW. (Other Meds: Avandia, Amaryl, Glucophage, Phenteramine, Lipitor, Lexapro, Toprol, & a 0.05 hormone patch. [Note: I take most all of these daily meds at late-night(bedtime). The only ones I take in a.m. are Phenteramine, and Loritab (1/2 pill). PLEASE TELL ME IF THERE IS/ARE ONE OR MORE OF THESE THAT CAUSE THE NAUSEA OR ANY OF THE OTHERS. THANK YOU VERY MUCH. (E-MAIL: ******)

I started taking Lisinopril about three months ago. I already have been taking Metroprolol, HCTZ, Paxil and Avandia. The Lisinopril gave me swollen, red, watery eyes; a persistent cough that gets so bad I puke; tightness in the chest and shortness of breath and extreme fatigue. My doctor keeps telling me it's all in my head, but I know it's not, I feel a lot worse than I did so I'm changing doctors. There has to be a better alternative.

In reading through everyone's posts, I feel better about my side effects, but it's really SAD that the doctors all think it's in our heads!

Can Avondia or Avandia cause blurry vision or sleepiness as a side effect?

I started taking Neurontin about 4 years ago.My neuroligist started me on it for Polyneuropathy(nerve damage in my feet and legs)He started me out on 300 mgs. (taking 2 three times a day) It was a miracle drug at first,since my feet had been hurting(burning,stinging,numb toes and balls of feet felt like I had been walking on sharp rocks bare footed and they were bruised)for 2 years.Then they started hurting again after I had been on it for 2 weeks.So he increased the dosage to 400mg taking it 2 three times a day and same thing happened.So he increased it to 800 mg. 2 three times a day.I started getting blisters on my tongue and alot of swelling in my feet,ankles and legs,so he decreased it and that all went away.So he slowing started increasing it and those didn't come back.
I went to another dr. because I moved and he decreased it because thought I was taking too much.And the pain became worse.Well I had ins. whenever I was taking it before and then I didn't have it anymore after about 8 months of being on it.It is so expensive so I had to cut way back on it because I couldn't afford to take the full dosage I was suppose to take.And that is how I know it works for the pain.While I was cut back on it,the pain was almost unbareable.I am taking 300 mg. 3 in the am,2 at noon and 3 at bedtime and my feet and legs still hurt,but I know from experience that if I wasn't on it I would be in unbearable pain.
I am on alot of various drugs.I also take Lamictal 25 mg. 1 four times a day for the neuropathy.And I also have fibromylgia.I seen where alot of people have fibro and it is being treated with this drug.It doesn't seem to help my fibro.Or maybe it would be alot worse if I wasn't on it.Don't know.I take Elavil 100mg. 1 at bedtime,Zanaflex 4mg. 1 at bedtime for the pain and fibro,Synthroid 0.1 mg. 1 a day,Pravachol 40 mg. 1 a day for high cholesterol,Metaglip 2.5-500 mg. 1 a day and Avandia 4 mg. 1 a day for diabeties and Vicoden 5 mg. & apap. 1 every 6 hours for pain.
The Neurontin seems to interact well with all these drugs.
I have dry mouth and some confusion which affects my ability to think and carry on multi-tasks.I am trying to get on my diability.I applied twice and was denied and I got a lawyer and we went to court before the judge 2 weeks ago and it will be 3 to 4 months before I hear if I am getting on it or not.