March 18th
2009
1:00 PM
I have type 2 diabetes for a few years and am 59 yrs old-and do not have fibromyalgia or kidney,liver problems or depression or a history of any painful muscles ever. I work up to 90 hrs a week as a doctor for the past 12 years and am a DIY renovator of my home in mt free time. I exercise regularly and am fairly fit, I do have a congenital mitochondrial myopathy characterized by non painful arm and leg muscle weakness- but have not been symptomatic significantly for 20 years. I take vitamins and one aspirin a day and have no medication allergies. weeks ago I started Januvia- my only diabetes medication. I worked well to normalize my mild to moserate elevation of BS.Over the past 2 weeks or so, I have had an increased somnolence without feeling rested upon awakening. I felt like I had been beaten with telephone poles and hammers, More distressing is the insidious onset of neuromuscular pains episodic sharp ones, more persistent aching and burning and tingling tingling, with a dense heaviness in legs more than arms worse with exertion and relieved by rest. 3 days ago it was to the point where I had to stop walking after 8 steps and could not climb a ladder beyond one step . I should not curl 2 lb weights even twice, Typing on a keyboard fatigued my arms after 5 minutes. I stopped Januvia three days ago, slept 30 hours,, felt better yesterday,restarted januvia last pm, Today, after 12 hours of sleep I feel exhausted like I did hard manual labor for a few days without ant sleep. The telephone pole beaten feeling returned, My weakness and pain are back with a vengeance and I cannot walk very well and have to stop typing this every 2 or 3 minutes to rest my arms, and have weakness also in my back muscles with curious sparing of abdominal muscles. Heat and massage do not help and are uncomfortable. I feel tired like I do when my myopathy acts up and my Krebs cycle is disrupted and thus my mitochondria do not make ATP to power my muscles- with the additional new symptom of significant pain. Aside from a mild tachycardia of about 100 at rest, my vital signs are normal, my cpk, Mg, thyroid function tests, comprehensive metabolic panel and sed rate are all normal . Heavy metal screen is negative. I will stop Januvia and probably never take it again, If my glucose goes back up I will go back to metformin which I took a few months about a year ago,
I suspect in my case that Januvia disrupted my mitochondrial function as well as being additionally toxic to my muscles and nerves by some additional pathogenesis, I question whether those individuals who have weakness, somnolence and neuromuscular symptoms might have some underlying mitochondrial dysfunction - a very under diagnosed condition - patients being told that their symptoms are of psychiatric origin.
November 20th
2007
10:23 AM
I was taking Danazol for 20years in alow dose for pressitant breast pain. I gradually began to suffer from muscle pains for no apparent reason. My doctor immediately stopped the Danazol, although wouldn't admit they were causing the problem. I ''fell apart at the seams''. None of my muscles worked properly, I had extremely high blood pressure, could barely walk, I was in constant pain and had to have massage for 2 hours per day. My eyes ached, I couldn't control my bladder and bowels very well. I thought I was going to die. My doctor sent me for numerous blood tests, endoscopes etc. But said I was depressed. I was depressed, because I felt so ill !
Its now 4 years since I stopped Danazol and I feel it has caused long term damage to my muscles. I have tried everything from massage to supplements. Things have improved a great deal, but I find it difficult to exercise as I tire very easily and particularly my back muscles seize up even after sitting for any length of time.
Has anyone else been on a low dose of Danazol for this length time. Have you suffered?
-- By avrilhall | Reply | (1) replies | Private Message me
July 6th
2007
7:37 PM
Basically I have nothing new to add, but to confirm the many reports here. I under went some Upper and Lower GI testing back in May, and to clear up some infections the doctor found, he put me on a 10 day course of Levaquin and 14 days of Metronidazole. After the 2nd day, I was very sore in every muscle and tendon in my body. I had been doing work in the garden and just thought it was from that, but a couple more days, the muscles in my calves and the tendons around my knees felt like they were being pulled out of my body and it didn't matter if I was at rest or up moving about. Getting up in the morning was excrutiating. It was all I could do to put weight on my legs, and my arms and back muscles felt like they were on fire. I also had headaches, but the muscle and tendon pain overshadowed anything else. Doctors need to know this very debilitating side effect of this drug, and prescribe it only in the most dire of cases, and not to anyone already suffering from joint, muscle or nerve disease. The flyer I received from the pharmacy had a brief warning about tendonitis..but listed it under additional side effects. This should be listed as a critical warning. It has been 2 months since I finished the prescription, and I am still having problems walking and a great deal of pain in my legs. The calf pain has mostly subsided, but the muscles in my calves still feel very tight and the tendons around my knees feel sore all the time. This is a very dangerous drug!
-- By lhoover649 | Reply | (1) replies | Private Message me
October 30th
2006
10:49 PM
I'm in my 30's. I have a similar experience with Guest #17721 posted Mon, 13 Feb 2006 with MethylPRED 4 mg on chest pain. Day 3 to 4, my neck & back muscles started aching. On Day 4, I felt easily angered and my heartburn feeling started. I ignored the slight discomfort thinking it was just stress related. Became concerned on Day 5 when the heartburn discomfort lingered, my right leg feels numb. I feel it was very likely induced by MethylPRED. I took 2 Asprins to ease the discomfort. I'll call my doctor tomorrow morning.
-- By e.leong | Reply | (1) replies | Private Message me
October 4th
2006
4:09 PM
I am not sure my symptoms are related to Lipitor, but it is the only med i was taking and when i finally suspected the connection 3 wk ago, i stopped taking it.
It occured to me that i was complaining of muscle and joint weakness in conversations with others, but related it to my age (53) and lack of exercise. Then i had a few episodes of sudden brief cramping in my back muscles -- totally unexplained by anything else -- and a couple episodes of dizziness, or true vertigo, while sitting and typing at my computer (i am a medical transcriptionist). Those got my attention. Come to find out my mother and brother also had identical muscle problems and switched their cholesterol medications away from Lipitor.
There are numerous other little things, running into walls and furniture, numbness in my feet or hands, yes, the cognitive things i've read here too, etc. Again, don't know if it is the medication, but after doing some reading of other's experiences, i do plan to do my best to improve my health withOUT the use of medication.
-- By judymari | Reply | Private Message me
June 14th
2006
12:51 AM
I am searching for Lipitor side effect and came across this website. Now I am convinced that what I am feeling are resulting from Lipitor.
I am taking (20mg/day) Lipitor for only a few weeks and I have unexplained patch of rash at the base of my neck, extreme headache, neck pain (it feels as if the back muscles in my neck could not support my head), muscle spasm, cold feet and joint pain. I am 42, otherwise healthy male (except for high cholesterol, 300). I began experiencing these symptoms and decided to search to see if I can find the causes. I could not find any resonable/plausible causes. I came acrross this site. Now, I think I will stop taking Lipitor and take my chances with the high cholesterol. I rather live a short life without a lot of pain and complications than to suffer a long life of pain and bitterness.
Good luck everyone!
April 12th
2006
3:53 PM
Trying to diagnose my problem with muscle problems has been dismal and I stopped taking lipitor 5 days ago when I felt I had to do something drastic. Initially discomfort, then pain, was in my neck. Over the last year it moved into my shoulders, then through my back muscles, into my buttocks, then into legs and recently also into my arms. I am a 64 year old female and I just can't continue to function properly with this complaint. My doctor has not even suggested that it might be lipitor but nothing else has worked out. I'm still really miserable. How long before some improvement and how much COQ10 should I take? (I was on 10mg lipitor for about 2 years)
-- By darmoyle | Reply | Private Message me
December 1th
2005
11:29 AM
I've been on this for 3 months and also take zyrtec. Both my calves cramp up and I strained my left calf muscle, so bad that I needed crutches and physical therapy. My hands feel achy like I have arthritis and my neck and back muscles feel tight. I'm going off this med at the end of the week.
-- By astropup | Reply | Private Message me
July 6th
2005
4:44 PM
After taking statins (Provacol, Lovastatin, Lipitor, and Zocor) for over 4 years and having strong muscle pains throught out my body, I stopped taking statins.
During this time the doctor tested me for everything else. I started taking Celebrex to stop the pain. It greatly reduced it.
However, i stopped Celebrex after how it might affect heart patients was made known.
Now 2 months after I stopped Lipitor, 95% plus of my pains are gone. I did not realize how severe they were until i stopped. one can get used to pain, but it does negatively affect you without you being consciously aware of it.
I now aggressively use diet and exercise to control my cholesterol. a better solution in all aspects.
when I started statins, i had no apparent side affects like muscle pain for about 10-12 months. however over time the pain started kept building and spreading. Eventually my legs muscles, back muscles, chest muscles, hip joints, elbow joints, and knee joints all ached.
A friend of mine who had been taking Lipitor (20mg) for a little over a year, recently started having muscle pains.
What I do not understand is why this side affect is not better know and published.
-- By jmahr | Reply | Private Message me
July 29th
2003
10:37 AM
I have experienced SEVERE stomach problems taking levoxyl. Since i stopped taking it, my stomach is back to normal. I wonder if anyone else has had a similar experience.I am NOW on ARMOUR THYROID...a natural product and feel NORMAL for the first time in three years. I hope the three years on levoxyl has not caused irrepairable damage to my digestive system!!
-- By carol439 | Reply | (3) replies | Private Message me
Lipitor (4) Yasmin (1) Methylpred DP (1) Levaquin (1) Lotrel (1) Levoxyl (1) Januvia (1) Danazol (1)
July 13th
2009
5:34 PM
Been taking Lotrel (at least 5 years), then generic without connecting the dots. Constant back pain, easly fatigued, leg muscle soreness, occasionally a swelling in the inside of the mouth over a couple of days until a layer of skin flakes off and goes away (to return many weeks later), light spotted rash on topside of forearms, muscle weakness in arms with arms elevated, definite loss of sex drive, no endurance, easily prone to heavy sweating, back muscles extremely tight and rigid causing pains when exerting with repeated constant motion, blood work showing muscle damage, possible short term memory issues and ability to concentrate, periods of times with the feeling of constrictions on the body compared to a inflated balloon walls stressed with pressure. Exercise (walking) causes a drop in blood pressure to normal (110-125/68-84) compared to 140/90+/-.
-- By fpk | Reply | Private Message me