July 9th
2009
6:43 PM
Can anybody tell me how long this lasts? I've been off it for a week and still no relief. The drug should be out of my system now. Any feedback would be appreciated.
-- By ratkos | Reply | (3) replies | Private Message me
April 30th
2009
1:14 AM
I was on 5/10 lotrel, a mild dose over 3 months. I took myself off of the drug and learned to relax more, and have a better diet and exercise more. I felt weird where I could not focus on my priorities, and the way the medication made me feel made me think of it more than I wanted to rather than life. I am normally a no headache person. While on the medication, i had horrible headaches where I had to take Excedrin migraine to get over it. My skin after taking it for awhile became dry and itchy. I had dark circles under my eyes, which was new. My knees and feet and hands became ice cold. I think it is because I believe that my blood pressure the way it was, was what my body needed, and maybe there was not enough circulation with the very low 117/60. My normal and feel good blood pressure is about 140/85. I am happy with that and will keep it. Also wild at normal 140/85 my blood sugar is normal. when I took the medication and it dropped to 117/60, my blood glucose rose. My body was releasing glucose because it was saying, hey something is not okay here. I think the drugs are bad, and now I eat organic vegetables, no coffee, no sugar, protein meats, and soy milk, unsweetened almond milk, walnuts, blueberries, whole grains. No white bread, no sugar, no soda, no fried food, no white potatoes, no white rice. My range is now 120/70 to 140/85 when i am rushing around. That is normal. I think medications change your body chemistry. When my skin became itchy and my extremities cold, and my body started shaking and freezing and sweating, it was from the pills. if you want to know you readings, don't go to the doctor. Buy a self test BP machine, Glucose reader, cholesterol meter. My doctors cholesterol count was 100 over another text i had at a free clinic. Maybe they cheat the numbers, who knows, to make you think you are sick and bring you back. take care of yourself, and get away from the fear and panic the doctors put you in. you are way better to see a natural nutritionist if you need help. Break a sweat every day!...that will help.
-- By nanwhite | Reply | Private Message me
December 8th
2008
9:31 AM
Prednisone is wonderful and horrible. I love it - asthma, copd - i can breathe, and I don't hurt as badly. I hate it - my blood glucose shoots to 300+ every day, my hands are so swollen I can't wear my wedding ring, my belly looks like I'm 8 months pregnant, plus a lot of the other side effects. BUT - I'm alive! I wouldn't be without it.
-- By bahaikat | Reply | Private Message me
December 4th
2008
10:56 AM
I was on prednisone while getting over pneumonia to help with my breathing. I was only on it for 7 days and the doctor didn't have me go off of it gradually. I missed the last dose on the 7th day and by bedtime, my muscles were sore enough it almost hurt to lay down. I took the last pill that night before I went to bed and had no muscle soreness in the morning. After that, the muscle soreness came back, along with dizziness. My pulse was also higher than normal. Two days later at night, I was still having muscle soreness and dizziness, although not nearly as but, but I was having a lot of trouble breathing and my pulse would refuse to go below 100 no matter what I did and the problems continued thought the night. The next morning I went to the clinic that prescribed me the predisone because the information they gave me said to see a doctor if these problems persisted. I told them I thought I might be having a predisone withdrawal because my mother, a nurse, said it was the most likely problem from experience. They completely ignored that saying it had been several days since I've stopped the steroid and kept asking me about my asthma (inhalers weren't working and it was definitely not an asthma attack -- I've had plenty of those, to all different degrees) and ended up giving me medicine for anxiety, which helped the closing of my throat, but none of my other symptoms. Three days later, my resting pulse is down to 80, but my breathing is so much worse than it would be with just my normal asthma and taking my inhalers as much as is allowed. I had no noticeable symptoms when I was on the prednisone except being less able to sleep. If it keeps up, I intend to go to a different doctor to see what is really happening, but I don't think it's 'normal' to have the withdrawal symptoms for this long after only having it for 7 days. I know I took it when I was younger (I'm 22), but I don't remember ever having issues going off of it before.
-- By breannatala | Reply | (4) replies | Private Message me
July 17th
2008
1:32 PM
Very disappointed...I became Hypoglycemic!
My story: I became Hypoglycemic within weeks of having the Mirena inserted. My symptoms were; anxiety, shakiness,irritability and nightmares.
I went to a primary care doctor and then to a endocrinologist complaining of that my blood sugar was becoming a problem. I was aware of the feeling of low blood sugar because when I breast feed my two boys (ages now 7 and 10) I then easily became hypoglycemic. However, I have not had this problem since.
Both physicians thought that i had reactive hypoglycemia because my fasting glucose was within normal limits.I have a healthy diet but i changed my eating habits even further (e.g. gave up all caffeine, sweets, alcohol. I started eating more whole grains and had small meals every 3 hours).
Even though I change my eating habits the side effects still became worse.I was starting to get panic attacks, I had never had these before. During one of my worst panic attacks (9 months after I had the Mirena inserted) I called my sister. I kept saying "I don't know what is causing me to be so anxious, I have never been like this before." Well, that statement sank in, I started to think about what was different. The only thing was the Mirena. That night I look up side effects of the Mirena and came across several blogs all describing their disappointment and many speaking about anxiety related issues.
I have to say I felt relief. It was not going crazy. The following day I read the official FDA Mirena web-site and that is when I found out about the effects on blood glucose. It is stated that Levonorgestrel may effect glucose tolerance and the blood glucose. However, my gynecologist never mentioned this side effect so I was not aware of this potential reaction. Btw, I had told both the primary care doctor and the endocrinologist that I had a Mirena IUD but neither of them new about the effects to the blood glucose.
The other interesting thing I noticed on the official FDA Mirena site is that when the list the Adverse reactions (depression,nervousness, weight gain etc...) they say reported by 5% or more subjects...hmmm, MORE...i think that is a key word!
I had it removed one month ago and I am starting to feel better. From what I understand, it may take up to 3 months to get the Levonorgestrel to get completely out of the system. however, my hypoglycemia is starting to diminish, I recently had a cup of coffee without getting the shakes and I can now enjoy a glass of wine at night too. My anxiety is almost completely gone.
What a relief to have figured this out!
-- By sooz1 | Reply | Private Message me
June 27th
2008
1:11 AM
I have been taking Atenolol since 2001. I take 75Mg each AM and am taking it for occasional Atrial Fib (AF) episodes. I have not had any physical impairment, or problems with being tired or problems things mentioned here. All in all, I have tolerated the Atenolol well. However, recently tried taking Lisinopril (only 4 days and I hate it and have all the problems you mention here and more) as it is suppose to help reduce AF.
HOWEVER, I have seen several significant metabolic side effects since I started taking the Atenolol I wanted to share. 1) I gained at least 20 LBS in the first year. 2) I became insulin resistant and saw my Triglycirides increase significantly (from the 200s to the 700s) and I have had to reduce carbs to keep them low, 3) I have seen my blood glucose (BG) levels rise resulting from the Atenolol. I have experimented and found my fasting BG levels in the AM are around 105 BEFORE taking the Atenolol, then within a hour of taking the Atenolol, they go up to 150-160 - that is without eating anything. Be aware of these implications. I am trying to find something as an alternative to Atenolol due to the BG levels, but have not yet. As I said, I tried Lisinopril, but that won't work.
-- By sps | Reply | Private Message me
April 14th
2008
1:05 PM
Here is one for you Artie. Maybe you can go find the statistical profile of studies regarding montelukast and CYP2C8. Originally it was hypothetized that montelukast would inhibit CYP2C8 thus inhibiting steroid (as an example) metabolize. In vitro studies predicted that. Then studies in vivo didn't confirm. Here is another one done in 2006.
Conclusions: Telithromycin increases the plasma concentrations and blood glucose–lowering effect of repaglinide by inhibiting its CYP3A4-catalyzed biotransformation and may increase the risk of hypoglycemia. Unexpectedly, montelukast has no significant effect on repaglinide pharmacokinetics, suggesting that it does not significantly inhibit CYP2C8 in vivo. The low free fraction of montelukast in plasma may explain the lack of effect on CYP2C8 in vivo, despite the low in vitro inhibition constant, highlighting the importance of incorporating plasma protein binding to interaction predictions.
http://www.nature.com/clpt/journal/v79/n3/abs/clpt2006320a.html
The question would be is that always the case or are there genetic variations among people that influence the outcome? Or is there potentially something else that we should be recognizing and we aren't doing that.
I thought of that again when I read this post. We obviously have many questions that should be answered especially when something that we don't expect happens.
Posted by Mindy Miller
Monday, April 14, 2008 4:39 AM EST
I am a pharmacy student and a mother of two sons that take Singular daily. My six year old has been taking it for 4 years, and my three year old for two years. They both have well controlled asthma. I wanted to reply to the questions many have posted about how long it takes to "get out of your system". The half life of Singular is 3-6 hours, so it is gone in a maximum of 18 hours. I came to this website while searching for information about recent FDA warnings. As far as I can tell, there are very few cases documented of mood changes and suicidal thoughts. There are many reasons why children have mood changes, and not feeling well because they have asthma and allergies could also be the source. I wonder if many who start Singular are also taking Prednisone, a steroid, to treat an asthma flare up. Steroids are definitely known to cause mood changes and is one of the reasons they can't be used long term. Please talk to your doctor or pharmacist before taking your children off of medication that may be helping them feel better in the long run.
If we had all of the answers, then there would not be such a wide range of symptoms that manifest themselves as a result of Singulair. So I am not trying to spread any conclusions that may be misleading. These are questions and not answers.
-- By concernedcitizen | Reply | (1) replies | Private Message me
November 4th
2007
10:30 AM
this product causes diabetes. It has raised my blood glucose 225 points. Very dangerous. Possibly these type meds is the reason for more diabetes as they are recklessly prescribed for people with congestive heart failure
-- By susanlee | Reply | (1) replies | Private Message me
March 16th
2007
8:44 AM
Type 1 diabetic and I have been for 13 years+. I want to know if any other diabetics out there experience a "different" smell and discharge after taking this pill... I have also experienced the same with Ortho Tri Cyclen- Lo........ about a year ago and I notified my Nurse Practioner. She recommended Yasmin. I know that a diabetic wonan's body is breeding ground for yeast infections if blood glucose is not uncontrolled consistentl. Can someone please give me some insight. Even thought my circulation is fine ,after reading the website and seeing all this about circulation etc... I am a little leiry.
-- By niya1922 | Reply | Private Message me
December 21th
2006
8:54 PM
I wanted to post for those going through a short course of prednisone and report that things will get better. I was prescribed prednisone at the ER for poison oak that had been getting worse over the course of 2 weeks; it looked like one knee was in the process of dissolving (soaked through 9 of those triple-layer 3x3 gauze pads in under an hour). I took 60mg for 3 days, 40mg for 3 days, and 20mg for 3 days. During that time I don't think I slept more than an hour total per night, I broke out in hives and cystic acne, and my face and stomach bloated. Then I had panic attacks as I was tapering off of the prednisone. At the end of a week after my last 20mg pill, I was almost euphoric at feeling like I was in my right mind again. All the other side-effects receded within 2 weeks and it does not seem to have had any lasting effects on my blood glucose (I'm part of a clinical trial for a vaccine). When I got reinfected with poison oak (that oil will hang around on anything it touches) I got a presciption for a topical corticosteroid from my GP and nipped it in the bud this time.
-- By simplegreen | Reply | Private Message me
June 20th
2006
12:59 AM
Kenalog is a steroid. I am diabetic and steroids really increase my glucose, the elevated glucose levels can cause heart palpitations, high blood pressure, etc. I check my blood glucose often after my injections and cover it with Insulin. This does decrease my heart palpitations and other side effects. The only other bad side effect is the severe depression after the shot. I was going through a particularly bad time anyway, and after the shot I was suicidal. The doctor should have warned me about depression, it would have helped to know it was caused by the kenalog.
-- By maled | Reply | Private Message me
PredniSONE (3) Yasmin (1) Atenolol (1) Lipitor (1) Torsemide (1) Lotrel (1) Lisinopril (1) Doxycycline Hyclate (1) Kenalog (1) Singulair (1) Januvia (1) Mirena (1)
July 24th
2009
6:09 PM
I am 33 yrs old. One night I was sleeping and about 12am, I woke up with my heart racing and I was having a squeezing feeling in my chest. I went to the ER and my blood pressure was extremely high. However, when they were running tests on me, they found that I hadn't had a heart attack and I was diabetic. The doctor gave me a stack of prescriptions to start taking. A few months later I went to see a different doctor, one that accepts my discount plan, and he took me off everything but metformin and 5 mg/day lisinopril. Since that night, the beginning of March, I am not the same person. I am keeping my diabetes under control, and my blood glucose is always in normal range. My last A1C test was 5.8. However, I am to the point of paranoia concerning the dead tingling feeling that I have in my feet. It is very on and off. There one minute then gone the next. It's not a feeling of numbness, because I can feel the slightest touch. Now from very little research I have already come to a conclusion that its the lisinopril. THE COUGH is enough to make me depressed and moody on its own, but now I'm thinking that my major mood swings are also coming from this drug. I cry all the time because I am worried that the diabetes is effecting my feet and that is what the doctors tell most people. My doctor said that I haven't been diabetic long enough to worry about neuropathy and that the sensation in my feet could be from a million things. Then almost every website I've looked at so far has hardly anything good to say about Lisinopril. I want to stop taking it, but don't have the money to afford an expensive medicine. what should I do? My blood pressure is usually around 102/68-70
-- By kslangley | Reply | (2) replies | Private Message me