Brain shivers symptoms and conditions

This is to serve as a personal warning to ANYONE taking
Effexor XR or thinking about taking it.

After my husband and I experienced HORRIBLE withdrawal symptoms within a week from coming off of our medication, and has continued for 4 months now. I feet compelled to inform people about the risks that this drug carries with it.

This drug helped my husband and I immensely while we were on it, but I just wish that I had been more knowledgeable about the risks of going off this medication so abruptly.

I understand that the medical professional that is prescribing you the drug is supposed to inform you that you are not to stop taking the medication abruptly (which is exactly what I was told). IN NO WAY was I told the consequences of NOT taking the medication.

So here are some of the symptoms that I experienced within the first two days (there are many more symptoms that other Effexor XR patients have experienced, but I feel that it is only right to list mine):

• Akathisia - a syndrome characterized by unpleasant sensations of "inner" restlessness that manifests itself with an inability to sit still or remain motionless.
• Ataxia – Loss of the ability to move the body with coordination.
• "Brain Zaps", "Brain Shocks," "Brain Shivers" or "Head Shocks" Descriptions include dizziness, electric shock-like sensations, sweating, nausea, insomnia, tremor, confusion, and vertigo.
• Cold Sweat – The skin is clammy and moist and you feel chilled. This is a reaction to a shock or pain as well as to fear and nervousness.
• Colitis – A condition where the large intestine becomes irritated from the use of the drug.
• Dehydration – An extreme loss of water from the body or the organs of the body as in sickness or not drinking enough fluids.
• Depersonalization - A feeling of watching oneself act, while having no control over a situation. (A sufferer feels that he or she has changed and the world has become less real, vague, dreamlike, or lacking in significance.)
• Diplopia – A condition where a person is looking a one object and instead of normally seeing just the one object he sees two. This is also call double vision.
• Disequilibrium - Dizziness, light-headedness and vertigo with a sense of losing balance.
• Dysarthria – The inability to control the mouth muscles when forming words so the words are not clearly spoken and heard.
• Gastric Irritation – An inflamed and sore stomach.
• Hyperhidrosis – The triggering of an excess of sweat being produced on the soles of the feet and/or the palms.
• Hypoesthesia – A partial loss of sensation or general loss of awareness.
• Influenza-like - Fatigue, lethargy, chills, sweating, headache, weakness and palpitations.
• Insomnia – Not able to fall asleep or sleeping for a shorter time than desired, thus not being able to properly rest and feeling un-refreshed. As a result, a person can become irritable, have difficulty concentrating and feel a lack of energy.
• Irritable Bowel Syndrome – A painful condition where the either the muscles or the nerves of the lower intestines, are not responding normally. This results in an alternating condition of diarrhea followed by constipation, back and forth.
• Mania – Unusually irrational, excessive and/or exaggerated behavior or moods ranging from enthusiasm, sexuality, gaiety, impulsiveness and irritability to violence.
• Mood Swings – An emotional shifting as from a state of happiness to a state of depression for a period of time.
• Night Sweats – With night sweats you become wide awake in the middle of the night shivering and cold and wet with your sheets/pajamas soaked in perspiration making it difficult to go back to sleep.
• Nightmare – Dreams that make you afraid or leave feelings of fear, terror, and upset long after waking up.
• Abnormal Orgasm – Unable to have an orgasm with normal sexual stimulation.
• Pain in Extremity – A painful feeling in the legs, arms, hands, and/or feet.
• Paresthesia - A sensation of tingling, pricking, or numbness of a person’s skin with no apparent long-term physical effect.
• Photopsia – A condition where a person sees lights, sparks, or colors in front of their eyes.
• Pressure of Speech – A condition where the individual cannot voice his ideas fast enough with the pressure of there being not enough time to say it.
• Pyrexia – Fever or the increase in body temperature that is usually a sign of infection.

Now some of you may be thinking that I might be overreacting, but I assure you that I am not. Quite the opposite actually, I feel that there are probably more symptoms that I am leaving out.
When I went online to research the symptoms that we had been experiencing, there was little information that I could find. I went onto the website for Wyeth (the company that produces Effexor XR) and the only thing that I could find was, and I quote,

“When people suddenly stop using or quickly lower their daily dose of EFFEXOR XR, discontinuation symptoms may occur. Talk to your doctor before discontinuing or reducing your dose of EFFEXOR XR.”

Wyeth also states that Effexor XR is, and I quote AGAIN,

“ Effexor XR Is Not Addictive. Effexor XR and other antidepressants are not addictive. You cannot become addicted to an antidepressant even if you take it for long-term maintenance therapy. An antidepressant is not a controlled substance like a narcotic or a stimulant.”

I am very sorry Wyeth, but I disagree.

DON'T TAKE EFFEXOR unless you want be on a med forever. I did not have any problems getting on it but after two years I am wanting to get off of it because I think I am in a much better place. I have been tapering off and I am down to 37.5 and I just cant get off of it. I was all the way up to 150 so you would think all the down to where I am that I could get off this. NOPE!!!! I hate it i hate it I hate it. I don't mind being on it but I just don't think I need it...... but I am thinking my body is telling me differently. This just sucks getting off of it!!!!

my BF has been taking antidepressants for 15 yrs- mostly a combo of lamictal and parnate. he is always depressed, has no energy, can't lose weight, suffers from chronic migraines (for which he downs handfuls of Tylenol and Excedrin) and constant muscle pain. i'm afraid to drive with him because of the road rage. his thinking is foggy, he is overwhelmed by every little thing and he constantly loses his keys, his phone- you name it. when he saw the commercials for AADD, he started to think he had that too and needed even more medicine!

i've had about all i can stand and in doing research, i found that niacin is useful for people with depression. it has to be the flushing kind and you need to take enough without flushing. some very depressed people have taken 12,000 mg a day and still not flushed!

so i started him on niacin and as we built up his dose, he cut down on the antidepressants. he got to 2000 mg of niacin a day and it took him 2 months to wean off the antiDs. he had minor brain shivers, but not nearly as bad or as many as when he has tried to get off the meds in the past

he has now been completely off the antiDs for 2 months and is taking between 300 - 500 mg of niacin daily.

here's what has happened: in 2 months, he has only had one headache and his muscle aches have gone; consequently he has only taken one Tylenol in the last two months as opposed to 10 a day like he used to. he has more energy- this Sunday when he got out of bed, he got active doing things instead of slumping on the couch for hours. i also almost fainted when i drove with him and he didn't scream when a pedestrian cut out in front of him. he is much more able to focus, he is not getting overwhelmed by everything.

and for the past 3 weeks at weight watchers, his weight has gone down a little

he is very happy about it.

I am a 49 year old female I took Cymbalta for 3 days and on the 4th morning I woke up with severe blurred vision and roaring in my ears that was April 26,2008. My ears are still ringing. I clenched my teeth so hard in my sleep I traumatized one of my upper molars which resulted in a root canal and crown. I have been to a ENT to have my ears checked, he said I had minimal hearing loss and gave me lipo flavonoid to take for the ringing. I just went to a neurologist today who is requesting an MRI on my brain to rule out a tumor. I don't know if this is a coincidence or not ,I know the clenching caused the damage to my tooth. The neurologist said ringing in the ears is not a side effect of Cymbalta. My life has been a nightmare since I took it.

I took Effexor XR for 6 months. The first week I couldn't sleep but that was the only side-effect, that is, until I quit. I decided to quit when I noticed that there was no difference in my mood and when I missed a day I would get a strange feeling. "Brain-shivers" is what they're described as. Almost like a drunk and wobbly feeling. After I stopped taking it the "shivers" lasted about 2 weeks and the first few days were the WORST! I went to the Dr. to get gradually get off but after taking the first one (37.5mg) and still felt the same - cold turkey is was! I wouldn't take it again. It didn't help and the withdrawal was terrible.

I love topamax.
I've been taking topamax for depression for 5 months. I started on 25 mgs a day, than worked my way up to 25 in the am and 25 in the pm, and now my doctor is moving me up to 50 in the am and 50 in the pm. I'm 31 years old, and have tried antidepressants since I was 17. I've struggled with depression since I was a kid. Antidepressants always made my depression worse, and caused me to get brain shivers because I don't tolerate serotonin drugs well. Antipsychotics for depression cause me to want to kill myself. Topamax was the only relief I have ever found.
The biggest side effect is sometimes I feel high or stoned like I smoked pot, especially if I am tired from not eating or pushing myself too hard. Most people don't get this, I just have a very strange brain chemistry.
Topamax works in the temporal lobe of your brain and can cause serious cognitive side effects if you do not already have damage in that part of your brain. That's why some people love it and some people hate it.
Weight loss isn't something I have experienced either, which sucks because I am overweight. I actually gained 10 pounds since being on topamax and I love carbonated beverages. But I am also the kind of person that quits smoking and loses 20 pounds, so I don't know if that will be true for you. I've also been way more thirsty since starting topamax, and my feet do fall asleep easier. But circulation improves if I practice a little yoga every day.
Don't be scared of this medication. It could really save your life.