Cholesterol drug symptoms and conditions

Today is 10/28. I am Weezie1 and I posted on 10/26 about my severe drug reactions. They have gotten worse since I wrote my first post. The fever and chills are gone. But now I have been dealing with a rash/hives over all parts of my body. They are worse where close contact to sleeping clothing are - back, chest, neck. The one side of my face that I usually sleep on is purple every morning, along with that same side of my neck. I managed to get myself back to the doctor on 10/26 and am now on a 6 day dosage of steroids for the rash/hives. The steroids have stopped the hives from getting any worse. But it is taking awhile to go away. Any heat, anxiety, frustration brings them out again. I see I will be dealing with this for awhile. I go back to the doctor on 10/29 for a recheck. I lost 2 days from work because of this. My skin felt like it was on fire with hundreds of bee stings. Now I feel like I have a severe case of poison ivy. I have found some relief using Aveeno's oatmeal powder to do a bathtub soaking at night. Then I follow that with Aveeno's rich moisturizing lotion. The doctor may want me on steroids for longer than first prescribed.....not a med you want to be on for too long. All because of an UTI last week that could have been simply treated with a regular antibiotic if my doctor was not able to prescribe this sulfa drug to me on 10/19. Next time I will go with my initial gut feeling and refuse to take a medication when I see its extensive side effect list. I wish I had done so last week. I am suffering much more now than I was last week with my UTI. I filed an online complaint at the FDA's website. They mention it at their phone number that Weezie1 reported in my 10/26 posting here. I, unfortunately, expect to see additional patient complaints here every few days when I check back at this great medications site. And now I see that someone has internal bleeding. What next? A death? My blood pressure and heart rate were both increased for several days due to this drug. I could feel my heart pounding when I was sitting still and laying in bed. Thankfully, my BP is normally on the low side, but all the numbers went up by 10. We have to band together to get this crap off the market and out of the hands of doctors and unsuspecting innocent patients. Our voices will be heard if we speak in large numbers. Keep talking!Good luck to all.

I am so annoyed that this medication is still on the market.
What is it going to take for it to be banned??? It took me almost one year to get my life back together. The side effects from this medication are horrible. Only the people who have gone through them know how severe it is. I had anxiety, insomnia, chills, numbing in the hands and feet, palpitations, vomiting, tremors, twitching, vision problems and the list goes on. My body was out of control. My blood tests were even coming back with all sort of problems thyroid, high blood sugar etc. When retested a few months later, everything was normal.
It took me lots of hard work to get myself back to normal. Thanks to Chinese medicine/acupuncture I now have my life back.
Please don't take Avelox!!!!!

I have been "sick" and in pain since taking Levaquin - first prescription before my sinus surgery in Jan. '09 and then again after the sinus surgery. I thought it was just taking me a along time to recover from the surgery for some reason but now as I read all the posts, I believe it was the levaquin. The joint pain, muscle pain, extreme fatigue continue to this date. I see the only lawsuits are for torn tendons but what about all of the other problems people are experiencing. Are we to live with this?

after 6 days of taking levaquin I developed severe shoulder and arm pain on both sides. Some days I can hardly use my arms. Lawyers don't want to take my case because I didn't suffer a rupture. What kind of crap is that? It's okay to have severe pain the rest of your life? My Dr. says it will go away. It's not. It's getting worse. Don't take this stuff unless you enjoy pain

My husband has been on Vytorin for a week or two and is complaining of tiredness and fatigue. I would like to know is anyone else has this problem

Three and a half years ago i suffered a heart attack, i had three stents put in and was put on Aspirin 75mg, Cardicor, 1.25mg, Tritace 5mg and Lipitor 80mg. I was fairly fit at the time, didn't drink or smoke and ate properly.

But now i'm suffering, i've been to the hospital and my GP, but are told there is nothing wrong, my hear tis good. So why am i suffering with light headedness, pains through my body, back, neck, chest, stomach. So much so i thought i had gall stones or kidney stones. My right knee can't be touched, it is so sore. Chest heaviness, eyesight getting worse, slurred speech, depression i could go on.

I've said this to my doctor, he just brushes it off and says i'm on them for life, ....apparently standard treatment for anyone who's had a heart attack. I walk 5 miles a day, eat 5 or more fruit and veg, don't smoke or drink, do all what i'm meant to. My cholesterol is really low, but so is the HDL too. I was never recommended CoQ10 or a vitamin B complex.

It was my mother who told me to research the side effects of all the meds i'm on. I agree, we all want to live a long and healthy life, but at what cost. I am now of the opinion that doctor's are so use to thinking they are near god like, they have forgotten that we are individuals, that we know our own bodies. I'm sick of the fact that the large pharmaceutical companies send out there sales reps to doctor's surgeries and that is what is deciding what the patients end up taking and not the patient's problem.

DOCTOR'S WAKE UP TREAT THE CAUSE NOT THE SYMPTOMS!!!!!!!

Less than 2 months after taking Lipitor I have been experiencing intense weakness of the legs, especially the hip area. A normally avid walker, last week really woke me up when I was unable to walk over 40 feet without having to stop from sheer leg exhaustion. I'd have to actually lean on my partner until I could manage to shuffle again- a shuffling gait is what I had to resort to just to make it back to the car.
This is bullshit because even though I've had some angina symptoms, right up until I went to the hospital I was able to hike; was still relatively strong.
So today I have spent hours researching side effects and have seen on this site alone many mentions of intense leg weakness and pain with Lipitor.
This, along with simultaneously educating myself on the truth about high cholesterol has convinced me to gradually cease taking this medication.

Instead I will replace with sufficient quantities of VitC, buckwheat combined with gingko, and of course I can never stop with the garlic because it is delicious.

Can anyone tell me if you can just stop Lipitor cold turkey or do you have to stop it slowly? I have been taking Lipitor for 5 years now and I have been trying to find out what is causing my leg weakness. I mentioned it to my doctor who said it si just a fact of getting older. The problem is getting worse and I noticed it started about 3 months after taking the Lipitor and has steadily gotten worse. I am 49 years old a little over weight {which I am working on}. I also noticed my asthma which I haven't delt with since a small child has come back. This may or may not have to do with the Lipitor but the pain in my knees and legs I believe do. It really hurts in the joints of my legs and sometimes in my shoulder area.

The risk of side effect of cholesterol lowering medication double and increase the risk of developing rhabdomyolysis if taken with these drugs. Fibrates(another type of cholesterol drug)
erythromycin(an antibiotic) ,Anti fungal medication
Niacin vit B3 at high dose( prescription doses) and cyclosporine ( an anti -rejection drug for patient who have had an organ donation) .these are from the book Australian S. C. she is liver doctor as well as extra research about cholesterol drug.her book title is Cholesterol the real truth
(are the drug you take making you sick).

took lipitor and erythromycin and now have neuropathy

I am 20 year old female and have a bad family history of high cholesterol, iv been taking 40mg/day of lipitor for nearly 2 months.

I have had Type 1 Diabetes for many years (54) without any complications of the disease - until I had a mild stroke. Which didn't affect me. Now my doctor makes me take Lipitor. From the very start of taking 10mg Lipitor per day, I got muscle cramps and leg twitches whilst in bed; muscle weaknesses; I even got Plantar Fasciitis and now I limp slightly in that foot. Before I took Lipitor I used to sleep like a baby. Lipitor has made me from a relatively healthy person despite having Diabetes to what feels like an old lady at aged 55. I know it is Lipitor as when I stop taking the drug all unpleasant side effects mentioned above cease. The trouble is my doctor won't give my Insulin without Lipitor and I need Insulin to live, of course. So I am forced to take Lipitor. I find that exercise such as a good long walk during the daytime helps; without it (eg in bad weather when I cannot get outside) the effects of Lipitor are much worse. My cholesterol readings and blood pressure are always good (even before the stroke) so why should I have to be almost crippled by Lipitor?

I started Lipitor 2 months ago, today is April 23, 2009.
1 month ago I started with Vertigo, doctors have tried many things to get rid of it but can't.
! week ago I started having trouble breathing, talking very short walks, problems still with vertigo, pain (headaches) on my left side, and I never have had headaches, pain in my neck left of the c-7 vertebrae.
Now 2 days ago I have problems swallowing food in the center of my chest, it really hurts, so now I am on an ice cream diet to figure things out.
I went to my doctor yesterday due to all my problems, which are all new in the past 7 weeks, and she did an x-ray, and blood work thinking I had a blood clot in my lungs.
At 6:30 pm last night 4-22-2009 she called me to go to the emergency room and have a cat scan done, and the results were I am loaded with lip-nodes in my chest and arm pits, and it look like cancer, so I have an appointment today at 2:00 pm to see what the plan of attack is.
God Bless,
L. G.
Biddeford, Maine

******

My husband has been taking Lipitor for a year. Several weeks after he started taking it he had muscle aches and when he went for a follow-up we discussed this concern and the neurologist said that it was ok and would go away. He had a stroke several years before and had some damage and he was tired. He complained about him getting weaker and his muscles hurting, he has left shoulder and arm pain. His chest hurts on the right side and doctors told him that he has inflammation between the muscle and chest wall but it has not cleared up after many months and meds. He is so weak now and is dropping things. He has some muscle twitching. I think it is from the Lipitor because the symptoms started after he was put on this drug. Doctor says that it is very unlikely..Has anyone else had these problems while taking Lipitor???

PLEASE HELP! My father, age 74, was on lipitor for a year or so and then was switched to zocor a few weeks ago to help control his cholestorol. In the past week, the tightening he experienced in his leg, while on lipitor, has become debilitating leg pain now while he is on Zocor. Ultrasounds have ruled out a blood clot. He has no pain when he sits, but he describes the pain has his calf wanting to explode when he stands and he cannot walk with out the help of a cain. The pain radiates from his leg up to his hip.

His cardiologist has taken him off the zocor for a few weeks to see if there is an improvement. It has been 3 days and he feels a bit of relief. SO here is the million dollar question: His labs indicate his cholestorol is normal now, most likely thanks to the statins.....can anyone suggest another form of meds that will help regulate his cholestorol....say COeq10 and fish oil? Any help is SO appreciated!!! Thanks to each of you for your posts. It is so comforting for my dad to know he isn't developing a new issue and that it can be resolved with the removal of zocor!

Class-Action Lawsuit Challenges Pfizer's DTC Ad Claim of Lipitor's Effectiveness in Reducing Cholesterol Levels, Wall Street Journal Reports
29 Sep 2005

A lawsuit filed by consumer advocates in U.S. District Court in Boston alleges that Pfizer marketed the cholesterol drug Lipitor to women and the elderly without proof that Lipitor reduces the risk of heart disease in those groups, the Wall Street Journal reports. The plaintiffs -- which include advocacy group Health Care for All and health plans for a New Jersey Teamsters union local, a Brooklyn woman and an elderly Massachusetts man -- allege that Pfizer's sales and marketing campaigns focused on cholesterol reduction and suggested that the medication protects against heart disease. However, there is a lack of proof that Lipitor's effect on cholesterol protects against heart attacks and strokes in women and the elderly with no prior history of the diseases, according to the suit. It also alleges that the company's marketing campaigns violated state consumer protection laws against unfair and deceptive trade practices. The plaintiffs state that although studies show the medication is helpful in lowering cholesterol in men with a high risk of cardiovascular disease, no such proof exists for women or the elderly. The groups are seeking compensation for women and the elderly who paid for Lipitor and insurance companies that paid for the medication on their behalf. A Pfizer spokesperson declined to comment on the suit, saying that the company had not been served, the Journal reports (Hensley, Wall Street Journal, 9/29).

I noticed that the FDA turned down approval for Merck's Cordaptive. That was the niacin cholesterol drug that came with it's own chemical to control the side effect of facial flushing.

I noticed that they were in clinical trials for montelukast's effect on preventing heart disease. So I guess that Merck is trying to capitalize on the "inflammation" angle that is mentioned below. Who shows up for these clinical trials?

http://clinicaltrials.gov/ct2/show/NCT00379808?term=%22montelukast%22+and+%22heart%22&rank=1

The surgeons can do liver and kidney transplants but there won't be enough organs to go around for all of us who get sold all of these drugs. But nobody does brain transplants. What are the people on montelukast long term going to do? And there will be many, many more of them if Merck gets approval for preventing heart disease.
-----------------------------------
http://blog.pharmexec.com/2008/05/01/mercks-cordaptive-a-nasty-surprise/

"The Merck drug was a nice piece of innovation: Kim’s elves figured out what causes niacin’s worst side effect, facial flushing, and developed a spanking new chemical, laropiprant, to control it. But since the cholesterol market is not exactly under served by pharma, you could also surmise that FDA is getting bearish on innovation there (more about that later).’s John Carey, apparently the only reporter not to be surprised, offers a must-read analysis of the situation.
http://www.businessweek.com/bwdaily/dnflash/content/apr2008/db20080429_182260.htm

“Add it all up and the FDA’s decision shouldn’t be seen as coming out of the blue. Cordaptive offers no big improvement over niacin alone—while introducing a new, unknown risk. And even the benefits of niacin’s effect on cholesterol may not be that big.”

“The decision also comes at a time when the very idea of cholesterol-lowering is under increasing scientific attack. Yes, doctors know that the statin class of cholesterol-lowering drugs, like Lipitor, do prevent heart disease and heart attacks. But there’s growing evidence that a big chunk of the benefits of statins comes from reducing inflammation,” writes John Carey.

Started to take Simvastatin, 40mg/day, 3 mts ago. Since a month got muscle pain in left arm, dizziness, skin being dry and more. I quit taking them on April 17th and the day after pain was gone and other symptoms as well. I know it seem weird but feel better now.

"Free at Last, Free at Last, Thank God I Am Free at Last" - That was my first thought as after two months, the horrible effects of Levaquin finally left my body. Don't give up hope, although with no support for doctors, it is hard not to! I just don't know why they are not interested in how bad the side effects can be with this drug - I received the same story - "out of the millions of prescriptions written, how many people have had adverse reactions"........well, with as severe as a reaction as I had with every joint, muscle and tendon in my body aching as though I had been hit with rheumatoid arthritis, and from all the other testimonials I have read, someone ought to be doing something about the toxic reactions to Levaquin. I was prescribed 750mg for 20 days and threw it in the trash after the 10th day. Honestly, after reading all the postings with people with similar symptoms, I cried not knowing how long this was going to last. I have posted previously that I don't know if it was a time coincidence or the fact that I went to a health food specialty store and was told to take Zyflamend A.M. & P.M, liquid magnesium and another liquid Cal/Mag/Zinc drink. I also took the largest dosage of Fish Oil (Omega 3) that I could find. I did this religiously for at least 3 weeks, so you may want to give it a try - one of my doctors said that it has to "work out of your system", but I can't think that the magnesium based products did help and they are godd for you also.

I am not a person inclined to sue anyone, but if there is a class action suit ever instituted against Levaquin, I would happily participate in the suit - this drug does things that I would never imagine an antibiotic would do.

Make sure to get on all you medical charts that you are allergic to Levaquin and related drugs in this category.

I also thank the day that I found this website as it relieved my mind to find out what was ailing me - I guarantee you that it would be a rare instance to have a doctor concur with the side effects!

Lawsuits Filed Over Lipitor Side Effects

By DAVID B. CARUSO

The Associated Press

Thursday, June 8, 2006; 9:33 PM

NEW YORK -- Two men who believe they suffered lasting muscle damage
from taking the popular anti-cholesterol drug Lipitor are suing
medication's maker, Pfizer Inc., claiming the company didn't issue
loud enough warnings about potential side effects.

Charles M. Wilson, a former insurance executive from Atlanta, and
Michael Mazzariello, an attorney from New York City, said in separate
lawsuits that they began experiencing debilitating pain, weakness and
memory problems after taking the drug.

"It ruined my life," said Mazzariello, 47. He said that within weeks
of going on the medication, he couldn't walk without a cane, tend his
garden or lift his 1-year-old child.

The symptoms subsided once Mazzariello stopped taking the medication _
he stood under his own power at a news conference Thursday at a
Manhattan hotel _ but he said he still suffers from pain, fatigue and
a tingling sensation in his hands and feet.

Pfizer called the two suits "baseless" and vowed to fight them in
court. A spokesman for the company, Bryant Haskins, said all potential
side effects of the drug are included on its labeling and often
mentioned in advertising.

Haskins said the number of Lipitor users experiencing those symptoms
is "very, very small ... well under 1 percent," and that they are far
outnumbered by the millions of people who have taken it safely.

Mark Krum, the lawyer handling the suits filed by Wilson and
Mazzariello, acknowledged that the medication may be safe for most
people, but he said that didn't absolve the company of its duty to
market it responsibly and adequately disclose side effects.

the following concerns another statin drug, crestor. since almost all statins work by blocking the pathway to make cholesterol....
By Lisa Richwine

WASHINGTON (Reuters) - Twenty-nine patients who took AstraZeneca Plc's cholesterol drug Crestor have developed kidney damage, a U.S. consumer group said on Friday as it called again for a ban on the medicine.

The rate of reported kidney problems is about 75 times higher with Crestor than with all other drugs in the same cl-------- combined, consumer group Public Citizen said. According to its analysis, there have been 6.4 reports of acute kidney failure or kidney damage for every 1 million Crestor prescriptions filled.

"It becomes clearer by the day that this drug is uniquely toxic without offering any unique benefit, and that it must be removed from the market," Dr. Sidney Wolfe, head of Public Citizen's Health Research Group, wrote in a letter to the Food and Drug Administration (news - web sites).

AstraZeneca insists Crestor, known generically as rosuvastatin, is as safe as other drugs in the family known as statins. The FDA (news - web sites) has agreed but promised to closely monitor reports of safety problems.

"Our data shows, with regard to that particular adverse event, it remains in line with other statins," company spokeswoman Emily Denney said. She added that AstraZeneca updates Crestor's reported health problems every week on its Web site www.rosuvastatininformation.com.

According to the site, "serious" kidney problems are "very rare" and occur at a rate of less than 1 in 10,000. Of all statin-related kidney problems reported to the FDA, 3.5 percent were related to Crestor as of early October, the site said.

Writing in this week's edition of The Lancet medical journal, AstraZeneca said Crestor's "safety profile is similar to those of the marketed statins. This view of the benefit-risk profile ... is shared by regulatory authorities in the 64 countries where rosuvastatin is approved."

The company's letter was written in response to earlier criticism from Wolfe.

Public Citizen said its latest analysis was based on reports to the FDA since Crestor's approval in September 2003 through Aug. 26, 2004. The reports of "adverse events" from doctors, patients, manufacturers and others do not prove if a drug caused a particular problem, but the FDA uses them to look for signals of possible drug-induced hazards.

Millions of people worldwide take statins, such as Pfizer Inc.'s Lipitor (news - web sites) and Merck & Co Inc.'s Zocor, to lower their cholesterol. High cholesterol is a major risk factor for heart disease.

Bayer AG's statin Baycol was pulled from the market in 2001 after it was linked to more than 100 deaths, many of them from a severe muscle-damaging condition called rhabdomyolysis.

The FDA has received 65 reports of rhabdomyolysis in Crestor patients, which is similar to the rate --------ociated with Baycol, Public Citizen said. AstraZeneca says the problem, also linked to other statins, is rare with Crestor.